Screening for ROS1 gene rearrangements in non-small-cell lung cancers using immunohistochemistry with FISH confirmation is an effective method to identify this rare target

Autor: Selinger, CI, Li, BT, Pavlakis, N, Links, M, Gill, AJ, Lee, A, Clarke, S, Tran, TN, Lum, T, Yip, PY, Horvath, L, Yu, B, Kohonen-Corish, MRJ, O'Toole, SA, Cooper, WA

AIMS: To assess the prevalence of ROS1 rearrangements in a retrospective and prospective diagnostic Australian cohort and evaluate the effectiveness of immunohistochemical screening. METHODS AND RESULTS: A retrospective cohort of 278 early stage lung

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______363::7aca2ce8ab00e484a5dcc1d2ba301ab2
https://hdl.handle.net/10453/162258

The histopathological spectrum and molecular changes associated with KRAS G12C mutation in non-small cell lung carcinoma.

Autor: Li JJ; Department of Anatomical Pathology, Liverpool Hospital, Liverpool, NSW, Australia; Ingham Institute for Applied Medical Research, Liverpool, NSW, Australia. Electronic address: jingjingli2001@gmail.com., Wu XJ; Department of Anatomical Pathology, Liverpool Hospital, Liverpool, NSW, Australia., Farzin M; Department of Anatomical Pathology, Liverpool Hospital, Liverpool, NSW, Australia., Bray V; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia., Williamson J; Department of Respiratory Medicine, Liverpool Hospital, Liverpool, NSW, Australia., Pal A; Ingham Institute for Applied Medical Research, Liverpool, NSW, Australia; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia; Department of Medical Oncology, Bankstown-Lidcombe Hospital, Lidcombe, NSW, Australia., Yip PY; Department of Medical Oncology, Campbelltown Hospital, Campbelltown, NSW, Australia., Hagelamin A; Department of Anatomical Pathology, Liverpool Hospital, Liverpool, NSW, Australia., Ding P; Department of Medical Oncology, Nepean Hospital, Kingswood, NSW, Australia; Crown Princess Mary Cancer Centre, Westmead Hospital, NSW, Australia., Nindra U; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia., Vinod S; Department of Radiation Oncology, Liverpool Hospital, NSW, Australia., French B; Department of Cardiothoracic Surgery, Liverpool Hospital, NSW, Australia., Chua W; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia; School of Medicine, Western Sydney University, Sydney, NSW, Australia., Gupta R; Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia; Sydney Medical School, Faculty of Medicine and Health, University of Sydney, NSW, Australia., Cooper WA; School of Medicine, Western Sydney University, Sydney, NSW, Australia; Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia; Sydney Medical School, Faculty of Medicine and Health, University of Sydney, NSW, Australia., Wang B; Department of Anatomical Pathology, Liverpool Hospital, Liverpool, NSW, Australia., Lee CS; Department of Anatomical Pathology, Liverpool Hospital, Liverpool, NSW, Australia; School of Medicine, Western Sydney University, Sydney, NSW, Australia; Department of Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia; South Western Sydney Clinical School, University of New South Wales, Liverpool, NSW, Australia. Electronic address: soon.lee@westernsydney.edu.au.

Publikováno v: Pathology [Pathology] 2024 Oct; Vol. 56 (6), pp. 786-794. Date of Electronic Publication: 2024 Jun 04.

Patients' perception of the benefits of palliative systemic therapy for advanced cancer.

Autor: Subramaniam S; NHMRC Clinical Trials Centre, Sydney, New South Wales, Australia.; Department of Medical Oncology, Bankstown Cancer Centre, Sydney, New South Wales, Australia.; Department of Medical Oncology, Concord Cancer Centre, Sydney, New South Wales, Australia.; University of Sydney, Sydney, New South Wales, Australia., Adams DH; Department of Medical Oncology, Macarthur Cancer Therapy Centre, Sydney, New South Wales, Australia.; Western Sydney University, Sydney, New South Wales, Australia., Tognela A; Department of Medical Oncology, Macarthur Cancer Therapy Centre, Sydney, New South Wales, Australia.; Western Sydney University, Sydney, New South Wales, Australia., Roncolato F; NHMRC Clinical Trials Centre, Sydney, New South Wales, Australia.; Department of Medical Oncology, Macarthur Cancer Therapy Centre, Sydney, New South Wales, Australia., Yip PY; Department of Medical Oncology, Macarthur Cancer Therapy Centre, Sydney, New South Wales, Australia.; Western Sydney University, Sydney, New South Wales, Australia., Lim SH; Department of Medical Oncology, Macarthur Cancer Therapy Centre, Sydney, New South Wales, Australia.; Western Sydney University, Sydney, New South Wales, Australia., Roohullah A; Department of Medical Oncology, Macarthur Cancer Therapy Centre, Sydney, New South Wales, Australia.; Western Sydney University, Sydney, New South Wales, Australia.; Department of Medical Oncology, Liverpool Cancer Therapy Centre, Sydney, New South Wales, Australia., Stockler MR; NHMRC Clinical Trials Centre, Sydney, New South Wales, Australia.; Department of Medical Oncology, Concord Cancer Centre, Sydney, New South Wales, Australia.; University of Sydney, Sydney, New South Wales, Australia.; Department of Medical Oncology, Chris O'Brien Lifehouse RPA, Sydney, New South Wales, Australia., Kiely B; NHMRC Clinical Trials Centre, Sydney, New South Wales, Australia.; Department of Medical Oncology, Concord Cancer Centre, Sydney, New South Wales, Australia.; University of Sydney, Sydney, New South Wales, Australia.; Department of Medical Oncology, Macarthur Cancer Therapy Centre, Sydney, New South Wales, Australia.

Publikováno v: Internal medicine journal [Intern Med J] 2024 May; Vol. 54 (5), pp. 735-741. Date of Electronic Publication: 2024 Jan 11.

Utility of multigene panel next-generation sequencing in routine clinical practice for identifying genomic alterations in newly diagnosed metastatic nonsmall cell lung cancer.

Autor: Nindra U; Department of Medical Oncology, Liverpool Hospital, Sydney, New South Wales, Australia.; Department of Medical Oncology, Macarthur Cancer Therapy Centre, Campbelltown Hospital, Sydney, New South Wales, Australia.; Department of Medical Oncology, Bankstown-Lidcombe Hospital, Sydney, New South Wales, Australia.; Ingham Institute for Applied Medical Research, Sydney, New South Wales, Australia., Pal A; Department of Medical Oncology, Liverpool Hospital, Sydney, New South Wales, Australia.; Department of Medical Oncology, Bankstown-Lidcombe Hospital, Sydney, New South Wales, Australia., Bray V; Department of Medical Oncology, Liverpool Hospital, Sydney, New South Wales, Australia., Yip PY; Department of Medical Oncology, Macarthur Cancer Therapy Centre, Campbelltown Hospital, Sydney, New South Wales, Australia.; Department of Medical Oncology, Bankstown-Lidcombe Hospital, Sydney, New South Wales, Australia.; Discipline of Pathology, School of Medicine, Western Sydney University, Sydney, New South Wales, Australia., Tognela A; Department of Medical Oncology, Macarthur Cancer Therapy Centre, Campbelltown Hospital, Sydney, New South Wales, Australia., Roberts TL; Department of Medical Oncology, Bankstown-Lidcombe Hospital, Sydney, New South Wales, Australia.; Discipline of Pathology, School of Medicine, Western Sydney University, Sydney, New South Wales, Australia.; South Western Clinical School, University of New South Wales, Sydney, New South Wales, Australia., Becker TM; Department of Medical Oncology, Bankstown-Lidcombe Hospital, Sydney, New South Wales, Australia.; Discipline of Pathology, School of Medicine, Western Sydney University, Sydney, New South Wales, Australia.; South Western Clinical School, University of New South Wales, Sydney, New South Wales, Australia., Williamson J; Department of Respiratory Medicine, Liverpool Hospital, Sydney, New South Wales, Australia., Farzin M; Department of Anatomical Pathology, Liverpool Hospital, Sydney, New South Wales, Australia., Li JJ; Department of Anatomical Pathology, Liverpool Hospital, Sydney, New South Wales, Australia., Lea V; Department of Anatomical Pathology, Liverpool Hospital, Sydney, New South Wales, Australia., Hagelamin A; Department of Anatomical Pathology, Liverpool Hospital, Sydney, New South Wales, Australia., Ng W; Department of Medical Oncology, Liverpool Hospital, Sydney, New South Wales, Australia.; Ingham Institute for Applied Medical Research, Sydney, New South Wales, Australia.; Discipline of Pathology, School of Medicine, Western Sydney University, Sydney, New South Wales, Australia.; South Western Clinical School, University of New South Wales, Sydney, New South Wales, Australia., Wang B; Department of Anatomical Pathology, Liverpool Hospital, Sydney, New South Wales, Australia., Lee CS; Ingham Institute for Applied Medical Research, Sydney, New South Wales, Australia.; Discipline of Pathology, School of Medicine, Western Sydney University, Sydney, New South Wales, Australia.; South Western Clinical School, University of New South Wales, Sydney, New South Wales, Australia.; Department of Anatomical Pathology, Liverpool Hospital, Sydney, New South Wales, Australia., Chua W; Department of Medical Oncology, Liverpool Hospital, Sydney, New South Wales, Australia.; Ingham Institute for Applied Medical Research, Sydney, New South Wales, Australia.; Discipline of Pathology, School of Medicine, Western Sydney University, Sydney, New South Wales, Australia.; South Western Clinical School, University of New South Wales, Sydney, New South Wales, Australia.

Publikováno v: Internal medicine journal [Intern Med J] 2024 Apr; Vol. 54 (4), pp. 596-601. Date of Electronic Publication: 2023 Sep 15.

Real world efficacy and toxicity of consolidation durvalumab following chemoradiotherapy in older Australian patients with unresectable stage III non-small cell lung cancer.

Autor: Stevens S; Department of Medical Oncology, Chris O'Brien Lifehouse, Sydney, 119-143 Missenden Road, Camperdown, NSW 2050, Australia; Department of Medical Oncology, Concord Cancer Centre, Concord Repatriation General Hospital, Sydney, Hospital Road, Concord, NSW 2139, Australia; School of Medicine, The University of Sydney, Camperdown, NSW 2006, Australia. Electronic address: Samuel.Stevens@health.nsw.gov.au., Nindra U; Department of Medical Oncology, Liverpool Hospital, Sydney, Cnr Elizabeth and Goulburn Street, Liverpool, NSW 2170, Australia; School of Medicine, University of New South Wales, Level 2, AGSM Building, Gate 11 Botany Street, Kensington, NSW 2052, Australia., Shahnam A; Department of Medical Oncology, Crown Princess Margaret Cancer Centre, Westmead Hospital, Sydney, Cnr Hawkesbury and Darcy Road, Westmead, NSW, Australia, 2145., Wei J; Department of Medical Oncology, Crown Princess Margaret Cancer Centre, Westmead Hospital, Sydney, Cnr Hawkesbury and Darcy Road, Westmead, NSW, Australia, 2145; School of Medicine, The University of Sydney, Camperdown, NSW 2006, Australia., Bray V; Department of Medical Oncology, Liverpool Hospital, Sydney, Cnr Elizabeth and Goulburn Street, Liverpool, NSW 2170, Australia., Pal A; Department of Medical Oncology, Liverpool Hospital, Sydney, Cnr Elizabeth and Goulburn Street, Liverpool, NSW 2170, Australia; Department of Medical Oncology, Bankstown-Lidcombe Hospital, Sydney, Eldrige Road, Bankstown, NSW 2200, Australia., Yip PY; Department of Medical Oncology, Macarthur Cancer Therapy Centre, Campbelltown Hospital, Sydney, Therry Road, Campbelltown, NSW 2560, Australia., Linton A; Department of Medical Oncology, Concord Cancer Centre, Concord Repatriation General Hospital, Sydney, Hospital Road, Concord, NSW 2139, Australia; School of Medicine, The University of Sydney, Camperdown, NSW 2006, Australia., Blinman P; Department of Medical Oncology, Concord Cancer Centre, Concord Repatriation General Hospital, Sydney, Hospital Road, Concord, NSW 2139, Australia; School of Medicine, The University of Sydney, Camperdown, NSW 2006, Australia., Nagrial A; Department of Medical Oncology, Crown Princess Margaret Cancer Centre, Westmead Hospital, Sydney, Cnr Hawkesbury and Darcy Road, Westmead, NSW, Australia, 2145; Department of Medical Oncology, Blacktown Cancer and Haematology Centre, Blacktown Hospital, Sydney, 18 Blacktown Road, Blacktown, NSW 2148, Australia; School of Medicine, The University of Sydney, Camperdown, NSW 2006, Australia., Lee J; Department of Medical Oncology, Chris O'Brien Lifehouse, Sydney, 119-143 Missenden Road, Camperdown, NSW 2050, Australia; Macquarie Medical School, Macquarie University, Wallumattagal Campus, Macquarie, NSW 2109, Australia., Boyer M; Department of Medical Oncology, Chris O'Brien Lifehouse, Sydney, 119-143 Missenden Road, Camperdown, NSW 2050, Australia; School of Medicine, The University of Sydney, Camperdown, NSW 2006, Australia., Kao S; Department of Medical Oncology, Chris O'Brien Lifehouse, Sydney, 119-143 Missenden Road, Camperdown, NSW 2050, Australia; School of Medicine, The University of Sydney, Camperdown, NSW 2006, Australia.

Publikováno v: Journal of geriatric oncology [J Geriatr Oncol] 2024 Mar; Vol. 15 (2), pp. 101705. Date of Electronic Publication: 2024 Jan 29.