Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Yinying Lu"'
Autor:
Xiufeng Liu, Feng Xia, Yue Chen, Huichuan Sun, Zhengqiang Yang, Bo Chen, Ming Zhao, Xinyu Bi, Tao Peng, Aizier Ainiwaer, Zhiwen Luo, Fusheng Wang, Yinying Lu
Publikováno v:
Liver Research, Vol 8, Iss 2, Pp 61-71 (2024)
Hepatocellular carcinoma (HCC), commonly known as primary liver cancer, is a major cause of malignant tumors and cancer-related deaths in China, accounting for approximately 85% of all cancer cases in the country. Several guidelines have been used to
Externí odkaz:
https://doaj.org/article/456149eddb5e4ca88a41aa055b751eea
Autor:
Xiufeng Liu, Yinying Lu, Weiping Zhou, Tao Peng, Jie Zhou, Huaqiang Bi, Feng Xia, Xiaoping Chen
Publikováno v:
Liver Cancer, Pp 1-21 (2024)
Background: Immune checkpoint inhibitor (ICI)-based combination therapy modalities for hepatocellular carcinoma (HCC) have achieved significant efficacy in clinical research and practice and have become the mainstay for the treatment of unresectable
Externí odkaz:
https://doaj.org/article/826540294f054ace936ba12ea0c45366
Publikováno v:
Synthetic and Systems Biotechnology, Vol 8, Iss 3, Pp 371-377 (2023)
Prime editing is a revolutionary gene-editing method that is capable of introducing insertions, deletions and base substitutions into the genome. However, the editing efficiency of Prime Editor (PE) is limited by the DNA repair process. Here, we show
Externí odkaz:
https://doaj.org/article/b331be1c9402447aa7bcd3d3d944cf14
Autor:
Guangyu Zhou, Shengyu Fu, Yunsen Zhang, Shuang Li, Ziang Guo, Defang Ouyang, Tianlei Ying, Yinying Lu, Qi Zhao
Publikováno v:
Antibodies, Vol 13, Iss 2, p 45 (2024)
Chimeric antigen receptor (CAR) T cell therapy shows promise in treating malignant tumors. However, the use of human epidermal growth factor receptor-2 (HER2) CAR-T cells carries the risk of severe toxicity, including cytokine release syndrome, due t
Externí odkaz:
https://doaj.org/article/96e8293353b84d2a817a5cb21e176ff3
Autor:
Li Gao, Lin Han, Qiaoling Wang, Yinying Lu, Binxia Chang, Hui Tian, Ang Huang, Xingran Zhai, Xueyuan Jin, Qingsheng Liang, Baosen Li, Huan Xie, Dong Ji, Zhengsheng Zou
Publikováno v:
eGastroenterology, Vol 2, Iss 1 (2024)
Background and aims To explore the incidence of alcohol-related hepatocellular carcinoma (HCC), evaluate possible synergisms between alcohol and well-known risk factors associated with HCC and establish a nomogram to predict alcohol-associated liver
Externí odkaz:
https://doaj.org/article/2127199a1bfb45c1937c58cde09f2462
Autor:
Yue Chen, Yutao Wang, Jin Lei, Bowen Chen, Xinfeng Zhang, Liangzheng Chang, Zhangli Hu, Yun Wang, Yinying Lu
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background and aims: Tyrosine kinase inhibitors (TKIs) combined with programmed cell death protein-1 (PD-1) have significantly improved survival in patients with unresectable hepatocellular carcinoma (uHCC), but effective biomarkers to predict treatm
Externí odkaz:
https://doaj.org/article/0e71c5bc10de423cb5be3e5aa34acd2f
Autor:
Meng Yu, Zhu Zhu, Yanqun Wang, Pingzhang Wang, Xiaodong Jia, Jie Wang, Lei Liu, Wanbing Liu, Yaqiong Zheng, Guomei Kou, Weiyan Xu, Jing Huang, Fengmin Lu, Xiajuan Zou, Shangen Zheng, Yinying Lu, Jincun Zhao, Hui Dai, Xiaoyan Qiu
Publikováno v:
Molecular Biomedicine, Vol 3, Iss 1, Pp 1-16 (2022)
Abstract Although the SARS-CoV-2 vaccine has been widely used worldwide, not all individuals can produce neutralization antibodies, so it is still urgent to find and prepare neutralization antibodies for COVID-19 prevention or treatment. In this stud
Externí odkaz:
https://doaj.org/article/1b0920b0d53d432f861d3f6efb1b6614
Autor:
Tao Yan, Lingxiang Yu, Ning Zhang, Caiyun Peng, Guodong Su, Yi Jing, Linzhi Zhang, Tong Wu, Jiamin Cheng, Qian Guo, Xiaoliang Shi, Yinying Lu
Publikováno v:
Cancer Biology & Medicine, Vol 19, Iss 6, Pp 802-817 (2022)
Hepatocellular carcinoma (HCC), one of the most common malignant tumors in China, severely threatens the life and health of patients. In recent years, precision medicine, clinical diagnoses, treatments, and innovative research have led to important b
Externí odkaz:
https://doaj.org/article/ed21bff4344b455f8f63e70de26f4518
Publikováno v:
Journal of Immunology Research, Vol 2023 (2023)
NOD-like receptor family pyrin domain containing 6 (NLRP6) is a new pattern recognition receptor in the mammalian innate immune system. Both the liver and the gut exhibit substantial levels of cytoplasmic expression. It can speed up cell response to
Externí odkaz:
https://doaj.org/article/7f1910f246e14d6ca642d7446276860e
Autor:
Fucun Xie, Bowen Chen, Xu Yang, Huaiyuan Wang, Ge Zhang, Yanyu Wang, Yunchao Wang, Nan Zhang, Jingnan Xue, Junyu Long, Yiran Li, Huishan Sun, Ziyu Xun, Kai Liu, Xiangqi Chen, Yang Song, Xiaobo Yang, Zhenhui Lu, Yilei Mao, Xinting Sang, Yinying Lu, Haitao Zhao
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundLenvatinib is a standard first-line systemic therapy in advanced hepatocellular carcinoma (aHCC) and is widely used in all lines. However, the efficacy and safety of immune checkpoint inhibitors (ICIs) plus molecular targeted agents (MTAs)
Externí odkaz:
https://doaj.org/article/fb348bd807e94787ae9b086c23530270