Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Yinuo, Wu"'
Autor:
Zhe Li, Mei-Yan Jiang, Runduo Liu, Quan Wang, Qian Zhou, Yi-You Huang, Yinuo Wu, Chang-Guo Zhan, Hai-Bin Luo
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 12, Pp 5357-5369 (2024)
Accurate receptor/ligand binding free energy calculations can greatly accelerate drug discovery by identifying highly potent ligands. By simulating the change from one compound structure to another, the relative binding free energy (RBFE) change can
Externí odkaz:
https://doaj.org/article/ff830aced8fd4213a2fd0578606f3c13
Autor:
Hongrui Zhang, Yinuo Wu, Hongbo Zhang, Nan Sun, Hongjiao Zhang, Bei Tian, Tanhang Zhang, Kexin Wang, Xu Nan, Huiui Zhang
Publikováno v:
Plant Signaling & Behavior, Vol 19, Iss 1 (2024)
MYB transcription factor is one of the largest families in plants. There are more and more studies on plants responding to abiotic stress through MYB transcription factors, but the mechanism of some family members responding to salt stress is unclear
Externí odkaz:
https://doaj.org/article/3a6d12d0ff97477988282f3b30072eec
Publikováno v:
Frontiers in Marine Science, Vol 11 (2024)
Cadmium (Cd) is a toxic heavy metal that, when present as a pollutant in the marine environment, is readily accumulated by marine bivalves, causing oxidative stress and tissue damage. This study explored whether short-term depuration could reverse Cd
Externí odkaz:
https://doaj.org/article/f9d3014166394371bac2f1acf74ce550
Autor:
Fei Xie, Licong Jiang, Yuanli Liu, Mingxiao Wang, Huanzhong Liu, Feng Jiang, Yinuo Wu, Yi-Lang Tang
Publikováno v:
BMC Psychology, Vol 11, Iss 1, Pp 1-8 (2023)
Abstract Background Depression, anxiety, and stress symptoms have been found to be associated with overweight or obesity, but the gender differences in the associations have not been well-examined. Based on a national sample of endocrinologists in Ch
Externí odkaz:
https://doaj.org/article/da5dfcb91b254759be0d2784547b389b
Autor:
Qian Zhou, Meiling Le, Yiyi Yang, Wenjuan Wang, Yuqi Huang, Quan Wang, Yijing Tian, Meiyan Jiang, Yong Rao, Hai-Bin Luo, Yinuo Wu
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 3, Pp 1180-1191 (2023)
Vascular dementia (VaD) is the second commonest type of dementia which lacks of efficient treatments currently. Neuroinflammation as a prominent pathological feature of VaD, is highly involved in the development of VaD. In order to verify the therape
Externí odkaz:
https://doaj.org/article/89a692e5759540968ac18e77b2bc7922
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 7, Pp 3103-3112 (2022)
Our previous study demonstrated that phosphodiesterase 8 (PDE8) could work as a potential target for vascular dementia (VaD) using a chemical probe 3a. However, compound 3a is a chiral compound which was obtained by chiral resolution on HPLC, restric
Externí odkaz:
https://doaj.org/article/41071af6cb6b437b842e31db8dbdb293
Publikováno v:
Journal of Occupational Medicine and Toxicology, Vol 16, Iss 1, Pp 1-5 (2021)
Abstract Objectives To investigate the sleep duration and level of satisfaction among physicians in tertiary public hospitals in China, and to explore associated factors. Methods A national online cross-sectional survey was conducted. Totally 20,786
Externí odkaz:
https://doaj.org/article/887a33badbec427e854fb26bf24c806d
Autor:
Yuncong Yang, Sirui Zhang, Qian Zhou, Chen Zhang, Yuqi Gao, Hao Wang, Zhe Li, Deyan Wu, Yinuo Wu, Yi-You Huang, Lei Guo, Hai-Bin Luo
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 12, Pp 2339-2347 (2020)
Optimization efforts were devoted to discover novel PDE10A inhibitors in order to improve solubility and pharmacokinetics properties for a long-term therapy against pulmonary arterial hypertension (PAH) starting from the previously synthesized inhibi
Externí odkaz:
https://doaj.org/article/ccae75c50048476bb23a4e31a9cef74b
Publikováno v:
Frontiers in Psychology, Vol 13 (2022)
ObjectiveTo survey the prevalence of burnout in a national sample of endocrinologists in China and to examine its correlates, with a special focus on gender differences.MethodsAn anonymous online survey was conducted among endocrinologists in 31 prov
Externí odkaz:
https://doaj.org/article/a20f19ce51eb4c96936986073c2a1072
Autor:
Feng Jiang, Linlin Hu, Ruiping Zhao, Huixuan Zhou, Yinuo Wu, Jeffrey J. Rakofsky, Tingfang Liu, Huanzhong Liu, Yuanli Liu, Yi-Lang Tang
Publikováno v:
BMC Psychiatry, Vol 19, Iss 1, Pp 1-11 (2019)
Abstract Background Measuring family members’ satisfaction with inpatient psychiatric care may help improve the quality of healthcare in psychiatric hospitals. This survey aimed to investigate the satisfaction of family members with inpatient psych
Externí odkaz:
https://doaj.org/article/a4c942728c9c4ca0b2210b5970a7f005