Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Yinsheng Wu"'
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-25 (2023)
Abstract How cells adapt their gene expression to nutritional changes remains poorly understood. Histone H3T11 is phosphorylated by pyruvate kinase to repress gene transcription. Here, we identify the protein phosphatase 1 (PP1), Glc7 as the enzyme t
Externí odkaz:
https://doaj.org/article/77215411af024a31a213731ce819da1c
Autor:
Yinsheng Wu, Lixu Tang, Han Huang, Qi Yu, Bicheng Hu, Gang Wang, Feng Ge, Tailang Yin, Shanshan Li, Xilan Yu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Little is known about the role of glycolysis in cellular senescence. Here, authors report that glycolysis-derived serine biosynthesis activates PKM2 to phosphorylate histone H3T11, prevent cell senescence, and promote healthy aging.
Externí odkaz:
https://doaj.org/article/07baa48aa70944c8bf3296fd8b903afe
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-8 (2022)
Abstract Background Displacement of the lesser trochanter (LT) is not uncommon after managing intertrochanteric femoral fractures and the influence of nonunion of the LT-fragment on clinical outcomes remains controversial. This study aimed to investi
Externí odkaz:
https://doaj.org/article/75c56cad5ca04dee8a85322489b11cb8
Autor:
Dan Zhao, Jinli Xiao, Lijuan Qiang, Xingwang Deng, Jingjing An, Qing Zhang, Fang Zhao, Jiaxiang Ma, Chao Fang, Guangyu Guan, Yinsheng Wu, Yan Xie
Publikováno v:
Acta Cirúrgica Brasileira, Vol 37, Iss 9 (2022)
ABSTRACT Purpose: To investigate the active ingredients of walnut ointment (WO) and its mechanism in repairing wounds. Methods: The ingredients of WO were detected by gas chromatography–mass spectrometry. The effect of linoleic acid (LA) was tested
Externí odkaz:
https://doaj.org/article/333ce5f3b4114b08864df6d97fc1ec87
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Cancer cells reprogram glucose metabolism to meet their malignant proliferation needs and survival under a variety of stress conditions. The prominent metabolic reprogram is aerobic glycolysis, which can help cells accumulate precursors for biosynthe
Externí odkaz:
https://doaj.org/article/270dac2dca7e467aa2a1bbc29372111a
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Cancer cells reprogram their metabolism to meet their demands for survival and proliferation. The metabolic plasticity of tumor cells help them adjust to changes in the availability and utilization of nutrients in the microenvironment. Recent studies
Externí odkaz:
https://doaj.org/article/3c59e092e04749c18906d0144c7c039c
Autor:
Xingwang Deng, Qian Chen, Lijuan Qiang, Mingwei Chi, Nan Xie, Yinsheng Wu, Ming Yao, Dan Zhao, Jiaxiang Ma, Ning Zhang, Yan Xie
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Hypertrophic scars formed after burns remain a challenge in clinical practice. Development of effective scar therapies relies on validated animal models that mimic human hypertrophic scars. A consistent porcine full-thickness burn hypertrophic scar m
Externí odkaz:
https://doaj.org/article/a04b34c1ebf642329f894ab43f7479e6
Autor:
Yuxiang Li, Lu Tang, Jianqiang Yu, Xiuying Dai, Wanfang Zhou, Wannian Zhang, Xiaoyan Hu, Shichu Xiao, Wen Ni, Xiuqiang Ma, Yinsheng Wu, Ming Yao, Guoxia Mu, Guangyi Wang, Wenjun Han, Zhaofan Xia, Hongtai Tang, Jijun Zhao
Publikováno v:
Trials, Vol 13, Iss 1, p 67 (2012)
Abstract Background Procedural burn pain is the most intense acute pain and most likely type of burn injury pain to be undertreated due to the physician’s fear of the adverse effect of analgesia and lack of anesthetist present. At our institution,
Externí odkaz:
https://doaj.org/article/b0e6e955ab20418a943919715cfa9f4c
Autor:
Dan Zhao, Yongzhao Zhu, Pan Xiaoliang, Lifeng Guan, Nan Xie, Yinsheng Wu, Yan Xie, Jiaxiang Ma, Xingwang Deng, Qian Chen, Lijuan Qiang, Zhang Qing, Zhao Fang
Publikováno v:
International Wound Journal. 19:1221-1231
Scars are common complications of burns and trauma, resulting in mental trauma, physical pain, and a heavy financial burden for patients. Specific and effective anti-scarring drugs are lacking in clinical practice. Phytochemicals are easily accessibl
Autor:
Xiaodong Lv, Zitong Zha, Jie Tang, Bicheng Hu, Xin Li, Jerry L. Workman, Xilan Yu, Jianguo Chen, Wanping Chen, Lixin Ma, Yinsheng Wu, Qi Yu, Shanshan Li
Publikováno v:
Nature Metabolism. 3:983-1000
Acetyl-CoA is a central node in carbon metabolism and plays critical roles in regulatory and biosynthetic processes. The acetyl-CoA synthetase Acs2, which catalyses acetyl-CoA production from acetate, is an integral subunit of the serine-responsive S