Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Yinshan Chen"'
Publikováno v:
Molecular Pharmaceutics. 18:3429-3438
Solubility enhancement has become a common requirement for formulation development to deliver poorly water soluble drugs. Amorphous solid dispersions (ASDs) and salt formation have been two successful strategies, yet there are opportunities for furth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da909b67a3413b55fb60d91f78e987b
https://doi.org/10.1021/acs.molpharmaceut.1c00325
https://doi.org/10.1021/acs.molpharmaceut.1c00325
Publikováno v:
The Journal of Physical Chemistry B. 121:7221-7227
Surface grating decay measurements have been performed on three closely related molecular glasses to study the effect of intermolecular hydrogen bonds on surface diffusion. The three molecules are derivatives of bis(3,5-dimethyl-phenylamino)-1,3,5-tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8736abf89fcff9b6ea84c4a64e681561
https://doi.org/10.1021/acs.jpcb.7b05333
https://doi.org/10.1021/acs.jpcb.7b05333
Publikováno v:
Chemical Engineering in the Pharmaceutical Industry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8d7f99c01ce6fb3409c02fa65e293b3
https://doi.org/10.1002/9781119600800.ch30
https://doi.org/10.1002/9781119600800.ch30
Publikováno v:
Pharmaceutical Research. 36
To inhibit the surface crystallization and enhance the dissolution of the basic amorphous drug clofazimine by polymer nano-coating. The free surface of amorphous clofazimine was coated by dip coating in an alginate solution at pH 7. The stability of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8845f8ff6c4ec0c83b2c61a911d1472e
https://doi.org/10.1007/s11095-019-2584-9
https://doi.org/10.1007/s11095-019-2584-9
Publikováno v:
The Journal of Physical Chemistry B. 121:444-449
Molecular glasses indomethacin and ortho-terphenyl were formed and fractured by cooling a liquid on a less thermally expansive substrate. In-plane tension was created by the mismatch of thermal expansion coefficients and accumulated to cause catastro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faf94d3a71e25ff1b0186abc996f3ba8
https://doi.org/10.1021/acs.jpcb.6b11347
https://doi.org/10.1021/acs.jpcb.6b11347
Publikováno v:
The Journal of Physical Chemistry B. 120:8007-8015
Surface-grating decay has been measured for three organic glasses with extensive hydrogen bonding: sorbitol, maltitol, and maltose. For 1000 nm wavelength gratings, the decay occurs by viscous flow in the entire range of temperature studied, covering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65a94bcc0b1af7765c1433c2610e1fd9
https://doi.org/10.1021/acs.jpcb.6b05658
https://doi.org/10.1021/acs.jpcb.6b05658
Publikováno v:
The Journal of chemical physics. 150(2)
Recent work has shown that diffusion and crystal growth can be much faster on the surface of molecular glasses than in the interior and that the enhancement effect varies with molecular size and intermolecular hydrogen bonds (HBs). In a related pheno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4967be2d71d313889de20a22f8c8be2
https://pubmed.ncbi.nlm.nih.gov/30646711
https://pubmed.ncbi.nlm.nih.gov/30646711
Publikováno v:
Journal of Non-Crystalline Solids. 429:122-128
The fracture of single-component molecular glasses has been characterized under tension. In-plane tension is created by cooling a liquid film below its glass transition temperature constrained on a substrate that is less thermally expansive. The frac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c07da41106b823c0b31d164389759f2f
https://doi.org/10.1016/j.jnoncrysol.2015.08.026
https://doi.org/10.1016/j.jnoncrysol.2015.08.026