Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yini Xiao"'
Autor:
Eleonora de Klerk, Yini Xiao, Christopher H. Emfinger, Mark P. Keller, David I. Berrios, Valentina Loconte, Axel A. Ekman, Kate L. White, Rebecca L. Cardone, Richard G. Kibbey, Alan D. Attie, Matthias Hebrok
Publikováno v:
JCI Insight, Vol 8, Iss 11 (2023)
Insulin secretion from pancreatic β cells is essential to the maintenance of glucose homeostasis. Defects in this process result in diabetes. Identifying genetic regulators that impair insulin secretion is crucial for the identification of novel the
Externí odkaz:
https://doaj.org/article/b4b5dbeb38934b90baccd9d13f8ca114
Autor:
Qing Ma, Yini Xiao, Wenjun Xu, Menghan Wang, Sheng Li, Zhihao Yang, Minglu Xu, Tengjiao Zhang, Zhen-Ning Zhang, Rui Hu, Qiang Su, Fei Yuan, Tinghui Xiao, Xuan Wang, Qing He, Jiaxu Zhao, Zheng-jun Chen, Zhejin Sheng, Mengyao Chai, Hong Wang, Weiyang Shi, Qiaolin Deng, Xin Cheng, Weida Li
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Immature function and fragility hinder application of hESC-derived β cells (SC-β cell) for diabetes cell therapy. Here, the authors identify ZnT8 as a gene editing target to enhance the insulin secretion and cell survival under metabolic stress by
Externí odkaz:
https://doaj.org/article/498f4e26b64740c4ac0e64e6b7a3344f
Autor:
Qing Ma, Yini Xiao, Wenjun Xu, Menghan Wang, Sheng Li, Zhihao Yang, Minglu Xu, Tengjiao Zhang, Zhen-Ning Zhang, Rui Hu, Qiang Su, Fei Yuan, Tinghui Xiao, Xuan Wang, Qing He, Jiaxu Zhao, Zheng-jun Chen, Zhejin Sheng, Mengyao Chai, Hong Wang, Weiyang Shi, Qiaolin Deng, Xin Cheng, Weida Li
Publikováno v:
Nature communications. 13(1)
Human embryonic stem cell-derived β cells (SC-β cells) hold great promise for treatment of diabetes, yet how to achieve functional maturation and protect them against metabolic stresses such as glucotoxicity and lipotoxicity remains elusive. Our si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f632c51609427c3735fc6e35147c42f
https://pubmed.ncbi.nlm.nih.gov/35922574
https://pubmed.ncbi.nlm.nih.gov/35922574
Publikováno v:
Earth Science-Journal of China University of Geosciences. 47:4256
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::171ebc26ae86d00c9aecc41ba7cc4d3a
https://doi.org/10.3799/dqkx.2022.291
https://doi.org/10.3799/dqkx.2022.291
Autor:
Xijie Wang, Xu Ma, Jiaxian Wang, Chenchen Wang, Ellen Poon, Haiyan Nan, Yini Xiao, Yuanfang Yu, Lingsong Li, Minglong Chen, Zhenhua Ni, Kenneth R. Boheler, Gang Yang, Xin Cheng, Chang Cui
Publikováno v:
ACS Applied Materials & Interfaces. 9:25929-25940
Human induced pluripotent stem cells (hiPSCs) can proliferate infinitely. Their ability to differentiate into cardiomyocytes provides abundant sources for disease modeling, drug screening and regenerative medicine. However, hiPSC-derived cardiomyocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ac220de4b08e52f2f22f6408f6c932
https://doi.org/10.1021/acsami.7b08777
https://doi.org/10.1021/acsami.7b08777
Autor:
Ma, Qing, Xiao, Yini, Xu, Wenjun, Wang, Menghan, Li, Sheng, Yang, Zhihao, Xu, Minglu, Zhang, Tengjiao, Zhang, Zhen-Ning, Hu, Rui, Su, Qiang, Yuan, Fei, Xiao, Tinghui, Wang, Xuan, He, Qing, Zhao, Jiaxu, Chen, Zheng-jun, Sheng, Zhejin, Chai, Mengyao, Wang, Hong
Publikováno v:
Nature Communications; 8/3/2022, Vol. 13 Issue 1, p1-16, 16p
Publikováno v:
Gastroenterology Week; 7/25/2023, p1730-1730, 1p
This is a unique book containing comprehensive coverage of pluripotent stem cell therapies for the treatment of diabetes. The greatest enthusiasm for treatment lies in the possibility of using stem cells to overcome the limits of islet transplantatio
