Zobrazeno 1 - 10
of 294
pro vyhledávání: '"Yingzi Cong"'
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-22 (2024)
Abstract Background Monocytes and macrophages play an indispensable role in maintaining intestinal homeostasis and modulating mucosal immune responses in inflammatory bowel disease (IBD). Although numerous studies have described macrophage properties
Externí odkaz:
https://doaj.org/article/6bbf5ac073c84548aac0dcc556b1b121
Autor:
Wenjing Yang, Tianming Yu, Xia Liu, Suxia Yao, Kamil Khanipov, George Golovko, Danyvid Olivares-Villagómez, Yingzi Cong
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
CD4+ T cells play a critical role in regulating autoimmune diseases, and intestinal microbial metabolites control various immune responses. Granzyme B (GzmB)-producing CD4+ T cells have been recently reported to participate in the pathogenesis of aut
Externí odkaz:
https://doaj.org/article/6025b6aa62494132a01479519c43d0dd
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 17, Iss 5, Pp 703-711 (2024)
Intestinal inflammatory fibrosis is a severe consequence of inflammatory bowel diseases (IBDs). There is currently no cure for the treatment of intestinal fibrosis in IBD. Although inflammation is necessary for triggering fibrosis, the anti-inflammat
Externí odkaz:
https://doaj.org/article/39d2c475929b4583b3fc635910b8ec0a
Autor:
Jun Sun, M. Nedim Ince, Clara Abraham, Terrence Barrett, Lisa A. Brenner, Yingzi Cong, Reza Dashti, Pradeep K. Dudeja, David Elliott, Thomas S. Griffith, Peter S. Heeger, Andrew Hoisington, Kaikobad Irani, Tae Kon Kim, Neeraj Kapur, Joseph Leventhal, Mansour Mohamadzadeh, Ece Mutlu, Rodney Newberry, Jonathan U. Peled, Israel Rubinstein, Salyka Sengsayadeth, Chen Sabrina Tan, Xiao-Di Tan, Eric Tkaczyk, Jason Wertheim, Zheng Jenny Zhang
Publikováno v:
Gut Microbes, Vol 15, Iss 2 (2023)
ABSTRACTThe present report summarizes the United States Department of Veterans Affairs (VA) field-based meeting titled “Modulating microbiome-immune axis in the deployment-related chronic diseases of Veterans.” Our Veteran patient population expe
Externí odkaz:
https://doaj.org/article/35f57b6f47564d71a10ebcf40edbc4b6
Autor:
Zheng Zhou, Wenjing Yang, Tianming Yu, Yu Yu, Xiaojing Zhao, Yanbo Yu, Chuncai Gu, Anthony J Bilotta, Suxia Yao, Qihong Zhao, George Golovko, Mingsong Li, Yingzi Cong
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTG-protein coupled receptor 120 (GPR 120) has been implicated in anti-inflammatory functions. However, how GPR120 regulates the neutrophil function remains unknown. This study investigated the role of GPR120 in the regulation of neutrophil fun
Externí odkaz:
https://doaj.org/article/5edc11f5c581405fb622b83cd839ccf5
Autor:
Wenjing Yang, Tianming Yu, Guangxi Zhou, Suxia Yao, Maki Wakamiya, Haitao Hu, Slobodan Paessler, Jiaren Sun, Yingzi Cong
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 15, Iss 5, Pp 1161-1179 (2023)
Background & Aims: T helper 1 (Th1) effector cells are implicated in inflammatory bowel disease. The stimulator of interferon genes (STING), an intracellular DNA sensor, has been shown to regulate infection and various cancers. However, whether and h
Externí odkaz:
https://doaj.org/article/7fa63b1e93ab47019179ffdd17d0a64c
Autor:
Jian Lin, Zhanjun Lu, Gengfeng Li, Cui Zhang, Huiying Lu, Sheng Gao, Ruixin Zhu, Hailiang Huang, Konrad Aden, Jianhua Wang, Yingzi Cong, Huili Wu, Zhanju Liu
Publikováno v:
Journal of Innate Immunity, Pp 1-21 (2022)
Monocyte chemotactic protein-1-induced protein-1 (MCPIP-1) is highly expressed in activated immune cells and negatively regulates immune responses, while the mechanisms underlying the immunoregulation of neutrophils in acute bacterial infection and l
Externí odkaz:
https://doaj.org/article/ad666af5515a493e9fe9085cfab422a4
Autor:
Ritian Lin, Caiyun Ma, Leilei Fang, Chunjin Xu, Cui Zhang, Xiaohan Wu, Wei Wu, Ruixin Zhu, Yingzi Cong, Zhanju Liu
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 4, Pp 1201-1221 (2022)
Background & Aims: TOB1 is an anti-proliferative protein of Tob/BTG family and typically involved in the tumorigenesis and T cell activation. Although TOB1 is associated with T helper 17 cell–related autoimmunity, its role in modulating T cell–me
Externí odkaz:
https://doaj.org/article/e51c608249b1448ab4029f2c53668b9c
Autor:
Ying Xiao, Haifeng Lian, Xiaoying S. Zhong, Srikruthi S. Krishnachaitanya, Yingzi Cong, Roderick H. Dashwood, Tor C. Savidge, Don W. Powell, Xiaowei Liu, Qingjie Li
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundPrevious studies implicated matrix metalloproteinases (MMPs), such as MMP-7, in inflammatory bowel diseases (IBD) by showing increased activity during inflammation of the gut. However, the pathophysiological roles of MMP-7 have not been cle
Externí odkaz:
https://doaj.org/article/670bbb529b8447fea1bf5c6bdeff3bf2
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Background and aims: Bowel obstruction (BO) causes not only gastrointestinal dysfunctions but also systemic responses such as sepsis, infections, and immune impairments. The mechanisms involved are not well understood. In this study, we tested the hy
Externí odkaz:
https://doaj.org/article/5f0e3fcdc3994e3db0e93edf9c8d04c4