Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Yingzhi Shen"'
Autor:
Guoming Li, Haojie Jiang, Lingbin Wang, Tingting Liang, Chen Ding, Mina Yang, Yingzhi Shen, Min Xin, Lin Zhang, Jing Dai, Xueqing Sun, Xuejiao Chen, Junling Liu, Yanyan Xu
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Impaired differentiation of megakaryocytes constitutes the principal etiology of thrombocytopenia. The signal transducer and activator of transcription 3 (STAT3) is a crucial transcription factor in regulating megakaryocyte differentiation, yet the p
Externí odkaz:
https://doaj.org/article/21b23dab49db463bbe2a89cab7515c1b
Autor:
Huiyan Sun, Xinxia Wang, Yongqiang Li, Yingzhi Shen, Lin Zhang, Yingjie Xu, Junling Liu, Xuemei Fan
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 938 (2024)
Hyperuricemia, i.e., increased plasma uric acid concentration, is a common problem in clinical practice, leading to gout or nephrolithiasis, and is associated with other disorders, such as metabolic syndrome, cardiovascular disease, and chronic renal
Externí odkaz:
https://doaj.org/article/371899d7624f4dee9428f2e6bc2e5aca
Autor:
Yan Geng, Lin Li, Jie Yan, Kevin Liu, Aizhen Yang, Lin Zhang, Yingzhi Shen, Han Gao, Xuefeng Wu, Imre Noth, Yong Huang, Junling Liu, Xuemei Fan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Currently, there is a lack of effective drugs for the treatment of pulmonary fibrosis. Here, the authors reveal a novel role of PEAR1 in fibroblast activation and demonstrate that activating PEAR1 by monoclonal antibodies might be a promising therape
Externí odkaz:
https://doaj.org/article/4024c5704dee455a89f3211c1bb337af
Autor:
Yingzhi Shen1, Jie Yan1, Lin Li1, Huiyan Sun1, Lin Zhang1, Guoming Li1, Xinxia Wang1, Ruoyan Liu1, Xuefeng Wu2, Baosan Han3, Xueqing Sun1 sunxueqing@shsmu.edu.cn, Junling Liu1,4 liujl@shsmu.edu.cn, Xuemei Fan1 fanxuemei@sjtu.edu.cn
Publikováno v:
Journal of Clinical Investigation. 8/15/2024, Vol. 134 Issue 16, p1-17. 17p.
Autor:
Yan Geng, Lin Li, Jie Yan, Kevin Liu, Aizhen Yang, Lin Zhang, Yingzhi Shen, Han Gao, Xuefeng Wu, Imre Noth, Yong Huang, Junling Liu, Xuemei Fan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/7bda36f28d5249bf940941207f8a67db
Autor:
Qidi Chen, Min Xin, Lingjun Wang, Lin Li, Yingzhi Shen, Yan Geng, Haojie Jiang, Yang Wang, Lin Zhang, Yanyan Xu, Yu Hou, Junling Liu, Xuemei Fan
Publikováno v:
Blood. 139(19)
Translation is essential for megakaryocyte (MK) maturation and platelet production. However, how the translational pathways are regulated in this process remains unknown. In this study, we found that MK/platelet–specific lactate dehydrogenase A (Ld
Autor:
Yan Geng, Lin Li, Jie Yan, Kevin Liu, Aizhen Yang, Lin Zhang, Yingzhi Shen, Han Gao, Xuefeng Wu, Imre Noth, Yong Huang, Junling Liu, Xuemei Fan
Publikováno v:
Nature communications. 13(1)
Pulmonary fibrosis is a chronic interstitial lung disease that causes irreversible and progressive lung scarring and respiratory failure. Activation of fibroblasts plays a central role in the progression of pulmonary fibrosis. Here we show that plate
Autor:
Xuemei Fan, Yang Wang, Xiaohong Cai, Yingzhi Shen, Tongran Xu, Yanyan Xu, Jinke Cheng, Xuefeng Wang, Lin Zhang, Jing Dai, Shuhai Lin, Junling Liu
Publikováno v:
Blood advances. 6(17)
The short life span of platelets is a major challenge to platelet transfusion services because of the lack of effective intervention. Here, we found that the accumulation of long-chain acylcarnitines (LCACs) is responsible for mitochondrial damage an
Autor:
Sun, Huiyan1 (AUTHOR), Wang, Xinxia1 (AUTHOR), Li, Yongqiang2 (AUTHOR), Shen, Yingzhi1 (AUTHOR), Zhang, Lin1 (AUTHOR), Xu, Yingjie1 (AUTHOR), Liu, Junling1,2 (AUTHOR) liujl@shsmu.edu.cn, Fan, Xuemei1 (AUTHOR) liujl@shsmu.edu.cn
Publikováno v:
Pharmaceutics. Jul2024, Vol. 16 Issue 7, p938. 20p.
Autor:
Geng, Yan, Li, Lin, Yan, Jie, Liu, Kevin, Yang, Aizhen, Zhang, Lin, Shen, Yingzhi, Gao, Han, Wu, Xuefeng, Noth, Imre, Huang, Yong, Liu, Junling, Fan, Xuemei
Publikováno v:
Nature Communications; 12/14/2022, Vol. 13 Issue 1, p1-1, 1p