A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency

Autor: Wendell Jones, Binsheng Gong, Natalia Novoradovskaya, Dan Li, Rebecca Kusko, Todd A. Richmond, Donald J. Johann, Halil Bisgin, Sayed Mohammad Ebrahim Sahraeian, Pierre R. Bushel, Mehdi Pirooznia, Katherine Wilkins, Marco Chierici, Wenjun Bao, Lee Scott Basehore, Anne Bergstrom Lucas, Daniel Burgess, Daniel J. Butler, Simon Cawley, Chia-Jung Chang, Guangchun Chen, Tao Chen, Yun-Ching Chen, Daniel J. Craig, Angela del Pozo, Jonathan Foox, Margherita Francescatto, Yutao Fu, Cesare Furlanello, Kristina Giorda, Kira P. Grist, Meijian Guan, Yingyi Hao, Scott Happe, Gunjan Hariani, Nathan Haseley, Jeff Jasper, Giuseppe Jurman, David Philip Kreil, Paweł Łabaj, Kevin Lai, Jianying Li, Quan-Zhen Li, Yulong Li, Zhiguang Li, Zhichao Liu, Mario Solís López, Kelci Miclaus, Raymond Miller, Vinay K. Mittal, Marghoob Mohiyuddin, Carlos Pabón-Peña, Barbara L. Parsons, Fujun Qiu, Andreas Scherer, Tieliu Shi, Suzy Stiegelmeyer, Chen Suo, Nikola Tom, Dong Wang, Zhining Wen, Leihong Wu, Wenzhong Xiao, Chang Xu, Ying Yu, Jiyang Zhang, Yifan Zhang, Zhihong Zhang, Yuanting Zheng, Christopher E. Mason, James C. Willey, Weida Tong, Leming Shi, Joshua Xu

Publikováno v: Genome Biology, Vol 22, Iss 1, Pp 1-38 (2021)

Abstract Background Oncopanel genomic testing, which identifies important somatic variants, is increasingly common in medical practice and especially in clinical trials. Currently, there is a paucity of reliable genomic reference samples having a sui

Externí odkaz: https://doaj.org/article/7cb57d840cc4477294d87b6e0d997c1a

A verified genomic reference sample for assessing performance of cancer panels detecting small variants of low allele frequency

Autor: Margherita Francescatto, Fujun Qiu, Jonathan Foox, Cesare Furlanello, Halil Bisgin, Daniel J. Craig, Chia Jung Chang, Kristina Giorda, Tao Chen, Sayed Mohammad Ebrahim Sahraeian, Yulong Li, Simon Cawley, Ying Yu, Zhihong Zhang, Yun-Ching Chen, Zhiguang Li, Dan Li, Vinay K. Mittal, Raymond Miller, Wendell D. Jones, Jianying Li, Marghoob Mohiyuddin, Zhining Wen, Rebecca Kusko, Gunjan Hariani, Yuanting Zheng, James C. Willey, Chen Suo, Todd Richmond, Wenzhong Xiao, Lee Scott Basehore, David P. Kreil, Dong Wang, Yutao Fu, Nikola Tom, Yifan Zhang, Zhichao Liu, Andreas Scherer, Carlos Pabón-Peña, Kira P. Grist, Meijian Guan, Giuseppe Jurman, Leihong Wu, Chang Xu, Katherine Wilkins, Jiyang Zhang, Anne Bergstrom Lucas, Barbara L. Parsons, Mehdi Pirooznia, Daniel Butler, Paweł P. Łabaj, Scott Happe, Marco Chierici, K. Miclaus, Suzy M. Stiegelmeyer, Daniel Burgess, Nathan Haseley, Kevin Lai, Weida Tong, Quan Zhen Li, Pierre R. Bushel, Donald J. Johann, Angela del Pozo, Yingyi Hao, Binsheng Gong, Guangchun Chen, Christopher E. Mason, Natalia Novoradovskaya, Joshua Xu, Tieliu Shi, Mario Solís López, Wenjun Bao, Leming Shi, J. Jasper

Publikováno v: Genome Biology
Genome Biology, Vol 22, Iss 1, Pp 1-38 (2021)

Background Oncopanel genomic testing, which identifies important somatic variants, is increasingly common in medical practice and especially in clinical trials. Currently, there is a paucity of reliable genomic reference samples having a suitably lar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d82f7a7065a20cfa1bf5bc4f2c04d890
http://hdl.handle.net/10138/337999

Drug-induced Rhabdomyolysis Atlas (DIRA) for Idiosyncratic Adverse Drug Reaction Management

Autor: Mike Mikailov, Yingyi Hao, Zhining Wen, Ruili Huang, Yu Liang, Weida Tong, Menglong Li, Zhichao Liu, Brian Delavan

Drug-induced rhabdomyolysis (DIR) is an idiosyncratic, rare and fatal adverse drug reaction (ADR) characterized in severe muscle injuries accompanied by multiple-organ failure. Limited knowledge and evidence regarding pathophysiology and natural hist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b54f402ab0689a878d6aae7929abfb2
https://europepmc.org/articles/PMC7050640/