Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Yingxia Hu"'
Autor:
Ping Ren, Yingxia Hu, Lei Peng, Luojia Yang, Kazushi Suzuki, Zhenhao Fang, Meizhu Bai, Liqun Zhou, Yanzhi Feng, Yongji Zou, Yong Xiong, Sidi Chen
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/15a5f16c0fbc450ab401029017a45f9f
Autor:
Lei Peng, Yingxia Hu, Madeleine C. Mankowski, Ping Ren, Rita E. Chen, Jin Wei, Min Zhao, Tongqing Li, Therese Tripler, Lupeng Ye, Ryan D. Chow, Zhenhao Fang, Chunxiang Wu, Matthew B. Dong, Matthew Cook, Guilin Wang, Paul Clark, Bryce Nelson, Daryl Klein, Richard Sutton, Michael S. Diamond, Craig B. Wilen, Yong Xiong, Sidi Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Despite effective vaccines against SARS-CoV-2, therapeutic options such as anti-virals and neutralizing antibodies are critical in treating disease, especially given the breakthrough infections of emerging VOCs. Here, Peng et al. generate two potent
Externí odkaz:
https://doaj.org/article/3c2da467436042e1868fd384b454c96c
Autor:
Min Zhao, Pei-Yi Su, Danielle A Castro, Therese N Tripler, Yingxia Hu, Matthew Cook, Albert I Ko, Shelli F Farhadian, Benjamin Israelow, Charles S Dela Cruz, Yong Xiong, Richard E Sutton, Yale IMPACT Research Team
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009683 (2021)
COVID-19 is a global crisis of unimagined dimensions. Currently, Remedesivir is only fully licensed FDA therapeutic. A major target of the vaccine effort is the SARS-CoV-2 spike-hACE2 interaction, and assessment of efficacy relies on time consuming n
Externí odkaz:
https://doaj.org/article/b2383cfe0cfb49c9beaf80ad8a7fdffc
Publikováno v:
Marine Drugs, Vol 19, Iss 2, p 53 (2021)
Macroalgae polysaccharides are phytochemicals that are beneficial to human health. In this study, response surface methodology was applied to optimize the extraction procedure of Pyropia yezoensis porphyran (PYP). The optimum extraction parameters we
Externí odkaz:
https://doaj.org/article/20b7dc94ffc44cfd97a25bf12258ea91
Autor:
Yingxia Hu, Ragna B. Gudnadóttir, Kirsten M. Knecht, Fidel Arizaga, Stefán R. Jónsson, Yong Xiong
Publikováno v:
Science Advances. 9
Lentiviral Vif molecules target the host antiviral APOBEC3 proteins for destruction in cellular ubiquitin-proteasome pathways. Different lentiviral Vifs have evolved to use the same canonical E3 ubiquitin ligase complexes, along with distinct noncano
Autor:
Yingxia Hu, Haijie Wu, Chenying Lu, Hanqing Xu, Boyang Li, Wanchun Guan, Mingjiang Wu, Yitian Gao, Haibin Tong
Publikováno v:
The Science of the total environment. 865
Cadmium (Cd) is a widely distributed toxic heavy metal that enters the environment via anthropogenic mobilization and accumulates in plants and animals, causing metabolic abnormalities even mortality. Although the toxic effects and stress damage of c
Autor:
Ping Ren, Yingxia Hu, Lei Peng, Luojia Yang, Kazushi Suzuki, Zhenhao Fang, Meizhu Bai, Liqun Zhou, Yanzhi Feng, Yongji Zou, Yong Xiong, Sidi Chen
Publikováno v:
bioRxiv
The SARS-CoV-2 variant, Omicron (B.1.1.529), rapidly swept the world since its emergence. Compared with previous variants, Omicron has a high number of mutations, especially those in its spike glycoprotein that drastically dampen or abolish the effic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38d3976546d48cfdf22a55272b9724d0
https://doi.org/10.1101/2022.08.09.503414
https://doi.org/10.1101/2022.08.09.503414
Autor:
Qi Shen, Kumari, Sushila, Chaoyi Xu, Sooin Jang, Jiong Shi, Burdick, Ryan C., Levintov, Lev, Qiancheng Xiong, Chunxiang Wu, Devarkar, Swapnil C., Taoran Tian, Tripler, Therese N., Yingxia Hu, Shuai Yuan, Temple, Joshua, Qingzhou Feng, Lusk, C. Patrick, Aiken, Christopher, Engelman, Alan N., Perilla, Juan R.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 3/28/2023, Vol. 120 Issue 13, Following p1-11, 39p
Autor:
Henry C. Nguyen, Vinay K. Pathak, Samantha J. Ziegler, Kai Zhang, Yong Xiong, Belete Ayele Desimmie, Hong-Wei Wang, Yingxia Hu, Tat Cheung Cheng, Jia Wang, John Chen
Publikováno v:
Nature structural & molecular biology
HIV-1 virion infectivity factor (Vif) promotes degradation of the antiviral APOBEC3 (A3) proteins through the host ubiquitin-proteasome pathway to enable viral immune evasion. Disrupting Vif-A3 interactions to reinstate the A3-catalyzed suppression o
Publikováno v:
Biochemistry
The apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3 (APOBEC3 or A3) family of proteins functions in the innate immune system. The A3 proteins are interferon inducible and hypermutate deoxycytidine to deoxyuridine in foreign single-s