Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Yingxia, Zheng"'
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-15 (2023)
Abstract Background Protein arginine methyltransferase 5 (Prmt5) is the main type II methyltransferase, catalyzes protein arginine residue symmetric dimethylation, and modulates normal cellular physiology and disease progression. Prmt5 inhibition or
Externí odkaz:
https://doaj.org/article/0df46311030448d0a19b5e72ea1ee749
Autor:
Bingxian Bian, Li Li, Xing Ke, Hui Chen, Yi Liu, Naisheng Zheng, Yingxia Zheng, Yanhui Ma, Yunlan Zhou, Junyao Yang, Lanshu Xiao, Lisong Shen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionCystoscopy is the standard methodology for diagnosis of bladder cancer (BC), but it is invasive and relatively expensive. Previous studies have found that urinary exosomal long non-coding RNAs (lncRNAs) may act as potential noninvasive bi
Externí odkaz:
https://doaj.org/article/e8ce74cc6da04160a3ed0d942bbf08bc
Autor:
Yingxia Zheng, Zheyi Chen, Yichao Han, Li Han, Xin Zou, Bingqian Zhou, Rui Hu, Jie Hao, Shihao Bai, Haibo Xiao, Wei Vivian Li, Alex Bueker, Yanhui Ma, Guohua Xie, Junyao Yang, Shiyu Chen, Hecheng Li, Jian Cao, Lisong Shen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Understanding the tumour microenvironment is essential for the efficacy of immunotherapies. Here the authors describe the immune landscape in esophageal squamous cell carcinoma and suggest several immunosuppressive mechanisms, which upon targeting ma
Externí odkaz:
https://doaj.org/article/405b3da8d64045049b0e81729e15379b
Autor:
Yingxia Zheng, Li Han, Zheyi Chen, Yiyang Li, Bingqian Zhou, Rui Hu, Shiyu Chen, Haibo Xiao, Yanhui Ma, Guohua Xie, Junyao Yang, Xianting Ding, Lisong Shen
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103785- (2022)
Summary: Immunotherapy targeting checkpoint blockade to rescue T cells from exhaustion has become an essential therapeutic strategy in treating cancers. Till now, little is known about the PD-L1 graphic pattern and characteristics in CD8+ T cells. We
Externí odkaz:
https://doaj.org/article/eb942055de53414a9a0d6b6e3ba986e7
Autor:
Rui Hu, Bingqian Zhou, Zheyi Chen, Shiyu Chen, Ningdai Chen, Lisong Shen, Haibo Xiao, Yingxia Zheng
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Protein arginine transferase 5 (PRMT5) has been implicated as an important modulator of tumorigenesis as it promotes tumor cell proliferation, invasion, and metastasis. Studies have largely focused on PRMT5 regulating intrinsic changes in tumors; how
Externí odkaz:
https://doaj.org/article/60d2f21e03ff42fe8455402c90c36c6a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Proinflammatory cytokine interleukin 32 (IL-32) is involved in infectious diseases and cancer, but what subtypes of immune cells express IL-32 and its roles in tumor microenvironment (TME) have not been well discussed. In this study, we applied bioin
Externí odkaz:
https://doaj.org/article/65a587fee0d2438aa98b23204136d9c1
Autor:
Bingxian Bian, Li Li, Junyao Yang, Yi Liu, Guohua Xie, Yingxia Zheng, Liang Zeng, Junxiang Zeng, Lisong Shen
Publikováno v:
Cancer Cell International, Vol 19, Iss 1, Pp 1-15 (2019)
Abstract Background Serum/plasma YKL-40 can be a useful index that is associated with tumor development. However, the prognostic value of serum/plasma YKL-40 in patients with solid tumors is still unclear. We aimed to utilize the existing literature
Externí odkaz:
https://doaj.org/article/f889005b3bc648e6b3bc2e16628529d8
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-10 (2017)
Abstract Background ICG-001, a small molecule, binds CREB-binding protein (CBP) to disrupt its interaction with β-catenin and inhibits CBP function as a co-activator of Wnt/β-catenin-mediated transcription. Given its ability to inhibit Wnt/β-caten
Externí odkaz:
https://doaj.org/article/7c1160b6cd7c4079b850c3bdeb03bec0
Autor:
Yingxia Zheng, Zheyi Chen, Bingqian Zhou, Shiyu Chen, Li Han, Ningdai Chen, Yanhui Ma, Guohua Xie, Junyao Yang, Hong Nie, Lisong Shen
Publikováno v:
The Journal of Immunology. 208:501-513
Protein arginine methyltransferase 5 (PRMT5) participates in the symmetric dimethylation of arginine residues of proteins and contributes to a wide range of biological processes. However, how PRMT5 affects the transcriptional and epigenetic programs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8beffad2e21284a9477ed4b15ca4d6ce
https://doi.org/10.4049/jimmunol.2100523
https://doi.org/10.4049/jimmunol.2100523
Autor:
Yingxia Zheng, Wensong Ge, Yanhui Ma, Guohua Xie, Weiwei Wang, Li Han, Bingxian Bian, Li Li, Lisong Shen
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Regulatory interleukin-10 (IL-10)-producing B cells (B10 cells) play a critical role in preventing and curing autoimmune diseases in experimental mouse models. However, the precise cellular and molecular mechanisms of action of B10 cells in humans, e
Externí odkaz:
https://doaj.org/article/1f763bd0d4b3438cb97fa7a5fa3fed1a