Zobrazeno 1 - 10
of 175
pro vyhledávání: '"Yingtian Pan"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Cocaine is a highly addictive drug, and its use is associated with adverse medical consequences such as cerebrovascular accidents that result in debilitating neurological complications. Indeed, brain imaging studies have reported severe reductions in
Externí odkaz:
https://doaj.org/article/deb1520255bc43a38a5de885f93fd135
Autor:
Yingtian Pan, Kicheon Park, Jiaxiang Ren, Nora D. Volkow, Haibin Ling, Alan P. Koretsky, Congwu Du
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
An imaging platform with self-supervised deep learning allows for the imaging of cerebral blood flows under the effect of cocaine in awake mice using 3D ultrahigh-resolution optical coherence Doppler tomography.
Externí odkaz:
https://doaj.org/article/d08766feac9e4c8f9fa36f6b6ac4bbcf
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-12 (2022)
Multimodal imaging of the mouse brain following acute cocaine application revealed that cocaine caused a biphasic calcium response in neurons, but not astrocytes, suggesting that these cells play different roles in mediating neurovascular coupling to
Externí odkaz:
https://doaj.org/article/c79b9a8b5b0c4b1382bd269e86309e70
Autor:
Congwu Du, Yueming Hua, Kevin Clare, Kicheon Park, Craig P. Allen, Nora D. Volkow, Xiu-Ti Hu, Yingtian Pan
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Individuals with substance use disorder are at a higher risk of contracting HIV and progress more rapidly to AIDS as drugs of abuse, such as cocaine, potentiate the neurotoxic effects of HIV-associated proteins including, but not limited to, HIV-1 tr
Externí odkaz:
https://doaj.org/article/5bee7691982b469bbc0d1ec27e5e6c57
Publikováno v:
NeuroImage, Vol 210, Iss , Pp 116554- (2020)
Spontaneous brain activity has been widely used to map brain connectivity. The interactions between task-evoked brain responses and the spontaneous cortical oscillations, especially within the low frequency range of ~0.1 Hz, are not fully understo
Externí odkaz:
https://doaj.org/article/84915a0f786440eeb5a531576149395c
Publikováno v:
Cell Reports, Vol 23, Iss 13, Pp 3878-3890 (2018)
Summary: The role of astrocytes in neurovascular coupling (NVC) is unclear. Here, we applied a multimodality imaging approach to concomitantly measure synchronized neuronal or astrocytic Ca2+ and hemodynamic changes in the mouse somatosensory cortex
Externí odkaz:
https://doaj.org/article/810807bd11144c7983fb5fe659ae1884
Publikováno v:
Frontiers in Pharmacology; 2024, p01-17, 17p
Cocaine affects both cerebral blood vessels and neuronal activity in brain. Cocaine can also disrupt astrocytes, which are involved in neurovascular coupling process that modulates cerebral hemodynamics in response to neuronal activity. However, sepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c831a672ef056e465d109c8073b92735
https://doi.org/10.21203/rs.3.rs-2626090/v1
https://doi.org/10.21203/rs.3.rs-2626090/v1
Autor:
Marina Fandaros, Yanzuo Liu, Yueming Hua, Yingtian Pan, David A. Rubenstein, Congwu Du, Wei Yin
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16c4d0b2959eb7ab5dff06c2637769b9
https://doi.org/10.1096/fasebj.2022.36.s1.r5052
https://doi.org/10.1096/fasebj.2022.36.s1.r5052
Publikováno v:
Addiction
BACKGROUND AND AIMS: The prefrontal cortex (PFC) is modulated by dopaminergic and glutamatergic neurons that project from the ventral tegmental area (VTA) and disruption of this modulation might facilitate impulsive behaviors during cocaine intoxicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9807f9ebe680464de7070cbafea200c
https://europepmc.org/articles/PMC9801493/
https://europepmc.org/articles/PMC9801493/