Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Yingquan Xiong"'
Autor:
Xin Chen, Yingquan Xiong, Shufei Zeng, Denis Delić, Mohamed Gaballa, Philipp Kalk, Thomas Klein, Bernhard K. Krämer, Berthold Hocher
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionSoluble guanylate cyclase (sGC) stimulators and activators are known to enhance kidney function in various models of chronic kidney disease (CKD) by increasing cyclic guanosine monophosphate (cGMP). Their differential effects on CKD progr
Externí odkaz:
https://doaj.org/article/3b8e296a1fa746699279d3c9445dec30
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-14 (2022)
Abstract Background Chronic kidney disease (CKD), characterized as renal dysfunction, is regarded as a major public health problem which carries a high risk of cardiovascular diseases. The purpose of this study is to evaluate the functional significa
Externí odkaz:
https://doaj.org/article/c77eed26349842249cfd4b3947513203
Autor:
Yingquan Xiong, Denis Delic, Shufei Zeng, Xin Chen, Chang Chu, Ahmed A. Hasan, Bernhard K. Krämer, Thomas Klein, Lianghong Yin, Berthold Hocher
Publikováno v:
BMC Nephrology, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background Host factors such as angiotensin-converting enzyme 2 (ACE2) and the transmembrane protease, serine-subtype-2 (TMPRSS2) are important factors for SARS-CoV-2 infection. Clinical and pre-clinical studies demonstrated that RAAS-blocki
Externí odkaz:
https://doaj.org/article/d0d3f6c070c84a6a9554fc0945f7e423
Head-to-head comparison of two SGLT-2 inhibitors on AKI outcomes in a rat ischemia-reperfusion model
Autor:
Chang Chu, Denis Delić, Jana Alber, Martina Feger, Yingquan Xiong, Ting Luo, Ahmed A. Hasan, Shufei Zeng, Mohamed M.S. Gaballa, Xin Chen, Lianghong Yin, Thomas Klein, Saban Elitok, Bernhard K. Krämer, Michael Föller, Berthold Hocher
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 153, Iss , Pp 113357- (2022)
The CREDENCE trial testing canagliflozin and the EMPA-REG OUTCOME trial testing empagliflozin suggest different effects on acute kidney injury (AKI). AKI diagnosis was mainly made based on changes of serum creatinine (sCr) although this also reflect
Externí odkaz:
https://doaj.org/article/6bf156b62ae1490c9a854bff0de67afa
Autor:
Xiaoli Zhang, Liping Liu, Mohamed M.S. Gaballa, Ahmed A Hasan, Yingquan Xiong, Li Xie, Thomas Klein, Denis Delic, Burkhard Kleuser, Bernhard K. Krämer, Jian Li, Berthold Hocher
Publikováno v:
Kidney & Blood Pressure Research (2022)
Introduction: The angiotensin-converting enzyme 2 (ACE2) as well as the transmembrane protease serine type 2 (TMPRSS2) have been found to play roles in cell entry for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing Cor
Externí odkaz:
https://doaj.org/article/a821c7266a894f01bf849f180a29b09d
Autor:
Chang Chu, Saban Elitok, Shufei Zeng, Yingquan Xiong, Carl-Friedrich Hocher, Ahmed A. Hasan, Bernhard K. Krämer, Berthold Hocher
Publikováno v:
BMC Nephrology, Vol 22, Iss 1, Pp 1-8 (2021)
Abstract Background Increased fibroblast growth factor 23 (FGF23) is a risk factor for mortality, cardiovascular disease, and progression of chronic kidney disease. Limited data exist comparing the association of either c-terminal FGF23 (cFGF23) or i
Externí odkaz:
https://doaj.org/article/84531fd523654deda3ee990caf57bbc1
Autor:
Shufei Zeng, Denis Delic, Chang Chu, Yingquan Xiong, Ting Luo, Xiaoyi Chen, Mohamed M.S. Gaballa, Yao Xue, Xin Chen, Yaochen Cao, Ahmed A. Hasan, Kai Stadermann, Sandra Frankenreiter, Lianghong Yin, Bernhard K. Krämer, Thomas Klein, Berthold Hocher
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 146, Iss , Pp 112606- (2022)
To date, the lowest protective SGLT2 inhibitor dose is unknown. We initially performed a dose-response pilot study in normal rats. Based on the results of this pilot study we compared the cardio-renal effects of the SGLT-2 inhibitor empagliflozin, wi
Externí odkaz:
https://doaj.org/article/ecf4c1bf89b94a07a853c6dc47c7eb19
Autor:
Xiaoli Zhang, Liping Liu, Mohamed M.S. Gaballa, Ahmed A. Hasan, Yingquan Xiong, Li Xie, Thomas Klein, Denis Delic, Burkhard Kleuser, Bernhard K. Krämer, Jian Li, Berthold Hocher
Publikováno v:
Kidney and Blood Pressure Research. 47:565-575
Introduction: The angiotensin-converting enzyme 2 (ACE2) as well as the transmembrane protease serine type 2 (TMPRSS2) have been found to play roles in cell entry for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus causing cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1dd9560b0b43dcbbe3352edc889f6e6
https://doi.org/10.1159/000525368
https://doi.org/10.1159/000525368
Publikováno v:
Cell Biology and Toxicology.
Hypercalcemia is a common complication in chronic kidney disease (CKD) and unfortunately contributes to nerve injury. This study aims to investigate the potential role and underlying mechanisms of Cinacalcet (CIN) in hypercalcemia-driven nerve injury
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::482ce30fcb3738b0298974304ccbf83e
https://doi.org/10.1007/s10565-022-09717-1
https://doi.org/10.1007/s10565-022-09717-1
Autor:
Steffen Rausch, Dieter Haffner, Florian Lang, Shufei Zeng, Katarina Horvathova, Yingquan Xiong, Chang Chu, Franz Schäfer, Bingbing Zhang, Michael Föller, Berthold Hocher, Bernhard K. Krämer, Martina Feger, Thomas Dschietzig, Torsten Slowinski, Uwe Querfeld, Ahmed A. Hasan
Publikováno v:
The FASEB Journal. 34:15269-15281
Fibroblast growth factor 23 (FGF23) and parathyroid hormone (PTH) are regulators of renal phosphate excretion and vitamin D metabolism. In chronic kidney disease (CKD), circulating FGF23 and PTH concentrations progressively increase as renal function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59918b80817a8be6279da15d3acd60c5
https://doi.org/10.1096/fj.202000596r
https://doi.org/10.1096/fj.202000596r