Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yingqiong Cao"'
Publikováno v:
BMC Public Health, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background High-frequency hearing loss is a significant occupational health concern in many countries, and early identification can be effective for preventing hearing loss. The study aims to construct and validate a risk model for HFHL, and
Externí odkaz:
https://doaj.org/article/4bb165b81b5b4325bcab4701aa7fead0
Publikováno v:
STAR Protocols, Vol 2, Iss 4, Pp 100912- (2021)
Summary: When cultured under typical conditions, human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are structurally and functionally immature. We have previously demonstrated that culture of hiPSC-CMs in maturation medium contain
Externí odkaz:
https://doaj.org/article/cea8cef6c9964162a3b0fc0f4e3e7703
Autor:
Hui Xu, Jiyong Wang, Qiwen Hu, Yun Quan, Huijie Chen, Yingqiong Cao, Chunbo Li, Ying Wang, Qun He
Publikováno v:
PLoS Genetics, Vol 6, Iss 9, p e1001132 (2010)
DNA methylation is involved in gene silencing and genome stability in organisms from fungi to mammals. Genetic studies in Neurospora crassa previously showed that the CUL4-DDB1 E3 ubiquitin ligase regulates DNA methylation via histone H3K9 trimethyla
Externí odkaz:
https://doaj.org/article/76483ab8831541f8a042e26dd2a060c9
Autor:
Roubina Tatavosian, Micah G. Donovan, Matthew D. Galbraith, Huy N. Duc, Maria M. Szwarc, Molishree U. Joshi, Amy Frieman, Ganna Bilousova, Yingqiong Cao, Keith P. Smith, Kunhua Song, Angela L. Rachubinski, Zdenek Andrysik, Joaquin M. Espinosa
Publikováno v:
Cell Death & Differentiation. 30:952-965
The p53 transcription factor is a master regulator of cellular responses to stress that is commonly inactivated in diverse cancer types. Despite decades of research, the mechanisms by which p53 impedes tumorigenesis across vastly different cellular c
Autor:
Weiyi Xu, Yingqiong Cao, Lorren Cantú, Eleni Nasiotis, Seema R. Lalani, Christina Y. Miyake, Lilei Zhang
Bi-allelic loss-of-function mutations in TANGO2 (Transport and Golgi Organization protein 2) cause a rare multiorgan genetic disorder. Despite normal cardiac function at baseline, patients may experience lethal cardiac arrhythmias during “crises”
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d177e792558d3c3fad2af67b1beb38fc
https://doi.org/10.1101/2022.06.27.497853
https://doi.org/10.1101/2022.06.27.497853
TANGO2-deficient disorder (TDD) is an autosomal recessive genetic disease caused by biallelic loss-of-function variants in TANGO2 gene. TDD-associated cardiac arrythmias are typically recalcitrant to standard antiarrhythmic medications and constitute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7aaa0331e94a0f2a68648853d4a0faa4
https://doi.org/10.21203/rs.3.rs-1778084/v1
https://doi.org/10.21203/rs.3.rs-1778084/v1
Autor:
Peter M. Buttrick, Yingqiong Cao, Brianna J. Klein, Timothy A. McKinsey, C. Y. Chi, Rushita A. Bagchi, Tatiana G. Kutateladze, Kunhua Song, Yuanbiao Zhao, Andrew S. Riching, Hongyan Xu, Etienne Danis
Publikováno v:
J Mol Cell Cardiol
SummaryDirect reprogramming of fibroblasts into cardiomyocytes (CMs) represents a promising strategy to regenerate CMs lost after ischemic heart injury. Overexpression ofGATA4,HAND2,MEF2C,TBX5, miR-1, and miR-133 (GHMT2m) along with transforming grow
Autor:
Joseph C. Cleveland, Angelo D'Alessandro, Michael R. Bristow, C. Y. Chi, Pilar Londono, Lori A. Walker, Mark Y. Jeong, Kunhua Song, Yuanbiao Zhao, Julie A. Reisz, Peter M. Buttrick, Genevieve C. Sparagna, Matthew R.G. Taylor, Benjamin C. Brown, Betty Bai, Yanmei Du, Kathleen C. Woulfe, Hongyan Xu, Timothy A. McKinsey, Amrut V. Ambardekar, Kathryn C. Chatfield, Ying-Hsi Lin, Walter E. Knight, Yingqiong Cao
Publikováno v:
Stem Cell Reports
Summary Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) are a powerful platform for biomedical research. However, they are immature, which is a barrier to modeling adult-onset cardiovascular disease. Here, we sought to develop
Autor:
Nathan J. Sniadecki, Kunhua Song, Michael A. Trembley, Eric M. Small, Peter M. Buttrick, Kevin M. Beussman, Andrea Leonard, Lori A. Walker, C. Y. Chi, Mark Y. Jeong, Walter E. Knight, Yuanbiao Zhao, Ellis Aune, Yingqiong Cao, Matthew R.G. Taylor, Pilar Londono, Hongyan Xu
Publikováno v:
Proceedings of the National Academy of Sciences. 116:556-565
Mutations in lysosomal-associated membrane protein 2 ( LAMP-2 ) gene are associated with Danon disease, which often leads to cardiomyopathy/heart failure through poorly defined mechanisms. Here, we identify the LAMP-2 isoform B (LAMP-2B) as required
Publikováno v:
BMC Public Health
BMC Public Health, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Public Health, Vol 21, Iss 1, Pp 1-11 (2021)
Background High-frequency hearing loss is a significant occupational health concern in many countries, and early identification can be effective for preventing hearing loss. The study aims to construct and validate a risk model for HFHL, and develop