Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Yingpinyapat Kittirat"'
Autor:
Kittiya Islam, Brinda Balasubramanian, Simran Venkatraman, Parichut Thummarati, Janpen Tunganuntarat, Nut Phueakphud, Phongthon Kanjanasirirat, Tanawadee Khumpanied, Pornparn Kongpracha, Yingpinyapat Kittirat, Rutaiwan Tohtong, Tavan Janvilisri, Patompon Wongtrakoongate, Suparerk Borwornpinyo, Nisana Namwat, Tuangporn Suthiphongchai
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract A poor outcome for cholangiocarcinoma (CCA) patients is still a clinical challenge. CCA is typically recognized by the desmoplastic nature, which accounts for its malignancy. Among various extracellular matrix proteins, laminin is the most p
Externí odkaz:
https://doaj.org/article/9bdbe8ba824c404bbbb92fb9ce9ecad8
Autor:
Thanaporn Kulthawatsiri, Yingpinyapat Kittirat, Jutarop Phetcharaburanin, Jittima Tomacha, Bundit Promraksa, Arporn Wangwiwatsin, Poramate Klanrit, Attapol Titapun, Watcharin Loilome, Nisana Namwat
Publikováno v:
PeerJ, Vol 11, p e16512 (2023)
Background Niclosamide is an oral anthelminthic drug that has been used for treating tapeworm infections. Its mechanism involves the disturbance of mitochondrial membrane potential that in turn inhibits oxidative phosphorylation leading to ATP deplet
Externí odkaz:
https://doaj.org/article/b3670b10c86940cf978c7d275eec5e82
Autor:
Pimpawadee Phukhum, Jutarop Phetcharaburanin, Kwuanjira Chaleekarn, Yingpinyapat Kittirat, Thanaporn Kulthawatsiri, Nisana Namwat, Watcharin Loilome, Narong Khuntikeo, Attapol Titapun, Arporn Wangwiwatsin, Tueanjit Khampitak, Manida Suksawat, Poramate Klanrit
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract The three-dimensional multicellular spheroid (3D MCS) model has been employed in cholangiocarcinoma research as it generates 3D architecture and includes more physiological relevance with the multicellular arrangement. However, it is also es
Externí odkaz:
https://doaj.org/article/83513aa574c84e43854fe8407571625e
Autor:
Yingpinyapat Kittirat, Manida Suksawat, Suyanee Thongchot, Sureerat Padthaisong, Jutarop Phetcharaburanin, Arporn Wangwiwatsin, Poramate Klanrit, Sakkarn Sangkhamanon, Attapol Titapun, Watcharin Loilome, Hideyuki Saya, Nisana Namwat
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cancer-associated fibroblasts (CAFs) are the dominant component of the tumor microenvironment (TME) that can be beneficial to the generation and progression of cancer cells leading to chemotherapeutic failure via several mechanisms. Nevertheless, the
Externí odkaz:
https://doaj.org/article/c2095a9c937440ce8c379cc33bde99c5
Autor:
Yingpinyapat Kittirat, Jutarop Phetcharaburanin, Bundit Promraksa, Thanaporn Kulthawatsiri, Arporn Wangwiwatsin, Poramate Klanrit, Sakkarn Sangkhamanon, Apiwat Jarearnrat, Suyanee Thongchot, Panupong Mahalapbutr, Watcharin Loilome, Hideyuki Saya, Nisana Namwat
Publikováno v:
Frontiers in Public Health, Vol 9 (2021)
Pyrvinium pamoate (PP), an FDA-approved anthelmintic drug, has been validated as a highly potent anti-cancer agent and patented recently as a potential chemotherapeutic drug for various cancers. The aims of this study were, therefore, to investigate
Externí odkaz:
https://doaj.org/article/26f8d29801aa445f9bcf5ec2a3d4ea10
Autor:
Malinee Thanee, Hasaya Dokduang, Yingpinyapat Kittirat, Jutarop Phetcharaburanin, Poramate Klanrit, Attapol Titapun, Nisana Namwat, Narong Khuntikeo, Arporn Wangwiwatsin, Hideyuki Saya, Watcharin Loilome
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0245871 (2021)
CD44 is a transmembrane glycoprotein, the phosphorylation of which can directly trigger intracellular signaling, particularly Akt protein, for supporting cell growth, motility and invasion. This study examined the role of CD44 on the progression of C
Externí odkaz:
https://doaj.org/article/378b2a5e730b4050a8fb87f296bb5594
Autor:
Bundit Promraksa, Praewpan Katrun, Jutarop Phetcharaburanin, Yingpinyapat Kittirat, Nisana Namwat, Anchalee Techasen, Jia V. Li, Watcharin Loilome
Publikováno v:
Biomolecules, Vol 11, Iss 3, p 476 (2021)
Cholangiocarcinoma (CCA) is a major cause of mortality in Northeast Thailand with about 14,000 deaths each year. There is an urgent necessity for novel drug discovery to increase effective treatment possibilities. A recent study reported that lignin
Externí odkaz:
https://doaj.org/article/9692ea8949b4460192148c9cf6bc1616
Autor:
Chanika, Worasith, Kulthida Y, Kopolrat, Opal, Pitaksakulrat, Chutima, Homwong, Yingpinyapat, Kittirat, Phattharaphon, Wongphutorn, Jiraporn, Sithithaworn, Paiboon, Sithithaworn
Publikováno v:
Am J Trop Med Hyg
Infection by Opisthorchis viverrini causes significant health problems, including cholangiocarcinoma (CCA); thus control and elimination of this trematode is an important strategy for the reduction of CCA. Currently, urine and copro antigen detection
Autor:
Yingpinyapat Kittirat, Nisana Namwat, Hasaya Dokduang, Malinee Thanee, Watcharin Loilome, Pattama Prommajun, Poramate Klanrit, Jia V. Li, Jutarop Phetcharaburanin, Prakasit Sa-Ngiamwibool
Publikováno v:
Cancer Genomics - Proteomics. 18:29-42
Background Opisthorchis viverrini (Ov) infection-induced cholangiocarcinoma (CCA) is a major public health problem in northeastern Thailand. Praziquantel was shown to prevent CCA development in an Ov-infected hamster model; however, the molecular mec
Autor:
Watcharin Loilome, Yingpinyapat Kittirat, Nisana Namwat, Chayanit Piyawajanusorn, Prakasit Sa-Ngiamwibool, Attapol Titapun
Publikováno v:
Cancer Genomics - Proteomics. 16:543-552
Background/aim This study examined the in vitro effects of the bile duct cancer drug PRIMA-1MET on cholangiocarcinoma (CCA) cell growth to determine its potential usefulness in CCA therapy. Materials and methods The effect of this drug on the express