Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Yingnan Huo"'
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 18, Iss 6, Pp 100778- (2023)
The number of people with Alzheimer's disease (AD) is increasing annually, with the nidus mainly concentrated in the cortex and hippocampus. Despite of numerous efforts, effective treatment of AD is still facing great challenges due to the blood brai
Externí odkaz:
https://doaj.org/article/5cb8133c491545baac757d4d86f4b263
Publikováno v:
Journal of Pharmaceutical Sciences. 110:2800-2807
The main objective of this paper is to elucidate the influence of drug-carrier compatibility and preparation method on the properties of Paclitaxel (PTX)-loaded lipid liquid crystalline nanoparticles (LLCNs). Here, glyceryl monooleate (GMO), glycerol
Autor:
Yingnan Huo, Chang Liu, Xin Zhang, Lu Qin, Shirui Mao, Hongbo Cheng, Zhixiang Cui, Jian Guan, Yujiao Sun
Publikováno v:
Journal of Controlled Release. 321:641-653
Macromolecular drugs, characterized by low stability and large molecular weight, still faced various difficulties by oral administration. And controlling drugs' release rate to reach the physiological concentration in the blood was recognized as one
Autor:
Li Wang, Yingnan Huo
Publikováno v:
10th International Symposium on Project Management (ISPM2022).
Publikováno v:
10th International Symposium on Project Management (ISPM2022).
Autor:
Li Wang, Yingnan Huo
Publikováno v:
10th International Symposium on Project Management (ISPM2022).
Autor:
Ying Sun, Yongqiang Kou, Xin Shen, Yingnan Huo, Shirui Mao, Chang Liu, Xin Zhang, Mingyue Gao, Zheng Sun
Publikováno v:
Journal of Pharmaceutical Sciences. 108:3623-3629
Nasal administration of insulin showed the attractive potential to improve the compliance of diabetic patients and alleviate mild cognitive impairment of Alzheimer's patients. However, the nasal absorption of insulin was not ideal, limiting its thera
Publikováno v:
Acta biomaterialia. 135
Mucoadhesive and mucopenetrating nanoparticles are commonly designed to improve mucosal drug delivery efficiency. Herein, in order to better understand the contribution of mucoadhesion and mucopenetration in oral delivery of biomacromolecules, insuli
Publikováno v:
Drug Delivery and Translational Research. 9:311-318
Drug delivery to the brain is limited by the blood-brain barrier (BBB). Intranasal delivery is a non-invasive route of drug administration which can bypass the BBB and contributed to a direct and rapid transport of drugs to the brain. However, intrin
Publikováno v:
International Journal of Pharmaceutics. 596:120297
Mucus penetration and intestinal cells targeting are two main strategies to improve insulin oral delivery efficiency. However, few studies are available regarding the effectiveness of combining these two strategies into one nano-delivery system. For