Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Yingna Xu"'
Autor:
Yingna Xu, Qiaofeng Liu, Chuan-Wei Chen, Qiuying Wang, Tianyuan Du, Run Yu, Qingtong Zhou, Dehua Yang, Ming-Wei Wang
Publikováno v:
Heliyon, Vol 10, Iss 15, Pp e35362- (2024)
Mahvash disease, a rare autosomal recessive metabolic disorder characterized by biallelic loss-of-function mutations in the glucagon receptor gene (GCGR), induces significant pancreatic hyperglucagonemia, resulting in α-cell hyperplasia and occasion
Externí odkaz:
https://doaj.org/article/e714057373e445b8b25705183134faf9
Autor:
Wenbo Feng, Qingtong Zhou, Xianyue Chen, Antao Dai, Xiaoqing Cai, Xiao Liu, Fenghui Zhao, Yan Chen, Chenyu Ye, Yingna Xu, Zhaotong Cong, Hao Li, Shi Lin, Dehua Yang, Ming-Wei Wang
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract Members of the melanocortin receptor (MCR) family that recognize different melanocortin peptides mediate a broad spectrum of cellular processes including energy homeostasis, inflammation and skin pigmentation through five MCR subtypes (MC1R
Externí odkaz:
https://doaj.org/article/190a738404d84ae2b0a114c2e0d96b21
Publikováno v:
Heliyon, Vol 9, Iss 9, Pp e19219- (2023)
Circular RNAs (circRNAs) are important non-coding RNAs (ncRNAs) involved in the development of multiple human diseases, especially cancers. circRNA_0084043 is significantly involved in the progression of melanoma. However, whether circRNA_0084043 is
Externí odkaz:
https://doaj.org/article/e940ebb00cdc4a18b36cfe3b17db37d2
A distinctive ligand recognition mechanism by the human vasoactive intestinal polypeptide receptor 2
Autor:
Yingna Xu, Wenbo Feng, Qingtong Zhou, Anyi Liang, Jie Li, Antao Dai, Fenghui Zhao, Jiahui Yan, Chuan-Wei Chen, Hao Li, Li-Hua Zhao, Tian Xia, Yi Jiang, H. Eric Xu, Dehua Yang, Ming-Wei Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Vasoactive intestinal polypeptide receptor 2 (VIP2R) is involved in immunity. Here, the authors report two cryo-EM structures of the VIP2R–Gs in complex with the endogenous peptide ligand PACAP27, revealing a unique interaction mode between PACAP27
Externí odkaz:
https://doaj.org/article/6b052b3574ad402e83e39dc0f3c97931
Autor:
Fenghui Zhao, Kaini Hang, Qingtong Zhou, Lijun Shao, Hao Li, Wenzhuo Li, Shi Lin, Antao Dai, Xiaoqing Cai, Yanyun Liu, Yingna Xu, Wenbo Feng, Dehua Yang, Ming-Wei Wang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 10/10/2023, Vol. 120 Issue 41, p1-12, 27p
Autor:
Xiao Liu, Qingtong Zhou, Jonathan R. Hart, Yingna Xu, Su Yang, Dehua Yang, Peter K. Vogt, Ming-Wei Wang
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Phosphoinositide 3-kinases (PI3Ks) are a family of lipid kinases that perform multiple and important cellular functions. The protein investigated here belongs to class IA of the PI3Ks; it is a dimer consisting of a catalytic subunit, p110α, and a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ace4881738541dcf4b0340014f9817
https://doi.org/10.1073/pnas.2215621119
https://doi.org/10.1073/pnas.2215621119
Circular RNAs (circRNAs) are important non-coding RNAs (ncRNAs) involved in the development of multiple human diseases, especially cancers. circRNA_0084043 is significantly involved in the progression of melanoma. However, whether circRNA_0084043 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aed127502bd1e1668a9123e72e1a678
https://doi.org/10.21203/rs.3.rs-2160496/v1
https://doi.org/10.21203/rs.3.rs-2160496/v1
Autor:
Jonathan R. Hart, Xiao Liu, Chen Pan, Anyi Liang, Lynn Ueno, Yingna Xu, Alexandra Quezada, Xinyu Zou, Su Yang, Qingtong Zhou, Steve Schoonooghe, Gholamreza Hassanzadeh-Ghassabeh, Tian Xia, Wenqing Shui, Dehua Yang, Peter K. Vogt, Ming-Wei Wang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 119(38)
Nanobodies and chemical cross-linking were used to gain information on the identity and positions of flexible domains of PI3Kα. The application of chemical cross-linking mass spectrometry (CXMS) facilitated the identification of the p85 domains BH,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55133b6f8776690dcbfd4a081e658996
https://pubmed.ncbi.nlm.nih.gov/36095215
https://pubmed.ncbi.nlm.nih.gov/36095215
Publikováno v:
Journal of Cancer
Glioma is a pervasive malignancy and the main cause of cancer-related deaths worldwide. Circular RNA is an important subject of cancer research, and its role and function in glioma are poorly understood. This study demonstrated that hsa_circ_0091581
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26fd28076e583bf3a50d912b14a1d969
https://doi.org/10.7150/jca.55558
https://doi.org/10.7150/jca.55558
Publikováno v:
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)REFERENCES. 28(5)
The neural basis of rosacea is not well understood. This study aimed to determine whether cerebral glucose metabolism (CGM) changes onEight adults with rosacea and 10 age/sex-matched healthy adults (controls) were enrolled in the study.Compared with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::534e69eccc602f691d691400967c787d
https://pubmed.ncbi.nlm.nih.gov/35644027
https://pubmed.ncbi.nlm.nih.gov/35644027