Zobrazeno 1 - 10
of 537
pro vyhledávání: '"Yingmei Zhang"'
Autor:
Haitao Li, Yingmei Zhang, Shengjin Fan, Dandan Li, Qian Zhang, Jinyue Fu, Dongxue Lu, Jiajuan Ji, Yinghua Li
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract This study was conducted to identify the characteristics and risk factors for early death in critically ill acute promyelocytic leukaemia (APL) patients in the Hemato-oncology ICU (HICU). A total of 44 APL patients from 2017 to 2023 were inc
Externí odkaz:
https://doaj.org/article/271a55b546e744b7a168960dd3643401
Publikováno v:
Redox Biology, Vol 72, Iss , Pp 103157- (2024)
Background: Doxorubicin (DOX) is a chemotherapeutic drug, while its clinical use is greatly limited by the life-threatening cardiotoxicity. N6-methyladenosine (m6A) RNA modification participates in varieties of cellular processes. Nonetheless, it rem
Externí odkaz:
https://doaj.org/article/360107e6bded4d67b7573551d9f4c5f6
Autor:
Shuolin Liu, Yaguang Bi, Tianting Han, Yiran E. Li, Qihang Wang, Ne Natalie Wu, Chenguo Xu, Junbo Ge, Ronggui Hu, Yingmei Zhang
Publikováno v:
Cell Discovery, Vol 10, Iss 1, Pp 1-23 (2024)
Abstract Inflammasome activation and pyroptotic cell death are known to contribute to the pathogenesis of cardiovascular diseases, such as myocardial ischemia-reperfusion (I/R) injury, although the underlying regulatory mechanisms remain poorly under
Externí odkaz:
https://doaj.org/article/35a8717ca6e747e8af85a8312821f616
Autor:
Yaguang Bi, Shuolin Liu, Xing Qin, Miyesaier Abudureyimu, Lu Wang, Rongjun Zou, Amir Ajoolabady, Wenjing Zhang, Hu Peng, Jun Ren, Yingmei Zhang
Publikováno v:
Journal of Advanced Research, Vol 55, Iss , Pp 45-60 (2024)
Introduction: Liver fibrosis is a life-threatening pathological anomaly which usually evolves into advanced liver cirrhosis and hepatocellular carcinoma although limited therapeutic option is readily available. FUN14 domain containing 1 (FUNDC1) is a
Externí odkaz:
https://doaj.org/article/a2fe01d001a7411dbd62d8473bb71797
Autor:
Wenjun Yu, Haixia Xu, Zhe Sun, Yuxin Du, Shiqun Sun, Miyesaier Abudureyimu, Mengjiao Zhang, Jun Tao, Junbo Ge, Jun Ren, Yingmei Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 12, Pp 4823-4839 (2023)
Clinical application of doxorubicin (DOX) is heavily hindered by DOX cardiotoxicity. Several theories were postulated for DOX cardiotoxicity including DNA damage and DNA damage response (DDR), although the mechanism(s) involved remains to be elucidat
Externí odkaz:
https://doaj.org/article/a05c0019ead24c4a826bd6513dbce8f0
Autor:
Miyesaier Abudureyimu, Xuanming Luo, Lingling Jiang, Xuejuan Jin, Cuizhen Pan, Wei Yu, Junbo Ge, Yingmei Zhang, Jun Ren
Publikováno v:
Redox Biology, Vol 70, Iss , Pp 103081- (2024)
Aims: Heart failure with preserved ejection fraction (HFpEF) is a devastating health issue although limited knowledge is available for its pathogenesis and therapeutics. Given the perceived involvement of mitochondrial dysfunction in HFpEF, this stud
Externí odkaz:
https://doaj.org/article/9ecf59cd6edc4cd6956426af92af67d3
Autor:
Jingjing Huang, Huayang Pan, Jing Sun, Jiaming Wu, Qiyue Xuan, Jinge Wang, Shanjia Ke, Shounan Lu, Zihao Li, Zhigang Feng, Yongliang Hua, Qingan Yu, Bing Yin, Baolin Qian, Menghua Zhou, Yanan Xu, Miaoyu Bai, Yingmei Zhang, Yaohua Wu, Yong Ma, Hongchi Jiang, Wenjie Dai
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-20 (2023)
Abstract Background The endoplasmic reticulum (ER) regulates critical processes, including lipid synthesis, which are affected by transmembrane proteins localized in the ER membrane. One such protein, transmembrane protein 147 (TMEM147), has recently
Externí odkaz:
https://doaj.org/article/174421d9f8bc465fa0bd11118096135b
Autor:
Litao Wang, Lin Wu, Yuxin Du, Xiang Wang, Bingsheng Yang, Shuai Guo, Yuan Zhou, Yiming Xu, Shuofei Yang, Yingmei Zhang, Jun Ren
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102893- (2023)
Background: DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is a novel instigator for mitochondrial dysfunction, and plays an important role in the pathogenesis of cardiovascular diseases. However, the role and mechanism of DNA-PKcs in angi
Externí odkaz:
https://doaj.org/article/0b0848831a1243188a7fce4133af0866
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 264, Iss , Pp 115480- (2023)
Gut microbiota plays a critical role in regulating the health and adaptation of wildlife. However, our understanding of how exposure to environmental heavy metals influences the gut microbiota of wild birds, particularly during the vulnerable and sen
Externí odkaz:
https://doaj.org/article/05d3f297b1924538af877d2dd7864a6f
Publikováno v:
Redox Biology, Vol 65, Iss , Pp 102812- (2023)
Background: Doxorubicin (DOX) is among the most widely employed antitumor agents, although its clinical applications have been largely hindered by severe cardiotoxicity. Earlier studies described an essential role of mitochondrial injury in the patho
Externí odkaz:
https://doaj.org/article/11e9d1272138432bac79fc786db54fab