Zobrazeno 1 - 10
of 409
pro vyhledávání: '"Yingliang, Wu"'
Autor:
Chenhu Qin, Xuhua Yang, Zheng Zuo, Peixin Yuan, Fang Sun, Xudong Luo, Xiangdong Ye, Zhijian Cao, Zongyun Chen, Yingliang Wu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Thermally stable full-length scorpion toxin peptides and partially degraded peptides with complete disulfide bond pairing are valuable natural peptide resources in traditional Chinese scorpion medicinal material. However, their pharmacologic
Externí odkaz:
https://doaj.org/article/41536166f86c485bb278f814d463069a
Publikováno v:
Insects, Vol 15, Iss 9, p 726 (2024)
Ecdysis is a well-known developmental feature among arthropods. Because the aggregate and synchronous molting of first-instar scorpions is markedly different from the common independent molting behavior of older scorpions and most arthropods, knowled
Externí odkaz:
https://doaj.org/article/e8e9791dbc2746738ec685f830b5ac15
Publikováno v:
Antibiotics, Vol 13, Iss 5, p 449 (2024)
Ticks transmit a variety of pathogens to their hosts by feeding on blood. The interactions and struggle between tick pathogens and hosts have evolved bilaterally. The components of tick saliva can directly or indirectly trigger host biological respon
Externí odkaz:
https://doaj.org/article/3c21569a58b0467a88249124a9222e9a
Publikováno v:
Pharmacological Research, Vol 197, Iss , Pp 106978- (2023)
Animal venom is an important evolutionary innovation in nature. As one of the most representative animal venoms, scorpion venom contains an extremely diverse set of bioactive peptides. Scorpion venom peptides not only are 'poisons' that immobilize, p
Externí odkaz:
https://doaj.org/article/c50675b43b2645bdbc2919e17a88bce3
Autor:
Weiwei Yu, Zhen Wang, Xiafei Yu, Yonghui Zhao, Zili Xie, Kailian Zhang, Zhexu Chi, Sheng Chen, Ting Xu, Danlu Jiang, Xingchen Guo, Mobai Li, Jian Zhang, Hui Fang, Dehang Yang, Yuxian Guo, Xuyan Yang, Xue Zhang, Yingliang Wu, Wei Yang, Di Wang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Potassium channels and membrane potential may influence macrophage function during inflammation. Here the authors show that the Kir2.1 potassium channel affects macrophage metabolism by altering cell surface retention of nutrient transporters and sub
Externí odkaz:
https://doaj.org/article/2158f62d8a164497818d6f09b2c1399a
Autor:
Shan Xu, Xin Sun, Leixuan Luo, Yang Yang, Qiuyan Guo, Sheng Tang, Zhiyan Jiang, Yuzhen Li, Jiaqian Han, Wenhui Gan, Feiyi Yang, Xuan Zhang, Yijun Liu, Chuanchuan Sun, Jie He, Meng Liu, Daiying Zuo, Wufu Zhu, Yingliang Wu
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 155, Iss , Pp 113537- (2022)
Breast cancer has become the most commonly diagnosed cancer, surpassing lung cancer, with 2.26 million new breast cancers worldwide in 2020. Hence, there is an urgent need to develop effective molecularly targeted therapeutic drugs to treat breast ca
Externí odkaz:
https://doaj.org/article/fefec4ccb42946699ef2c27b7c718346
Autor:
Chenhu Qin, Xuhua Yang, Yuanyuan Zhang, Gang Deng, Xin Huang, Zheng Zuo, Fang Sun, Zhijian Cao, Zongyun Chen, Yingliang Wu
Publikováno v:
Toxins, Vol 15, Iss 5, p 340 (2023)
Thermally processed Buthus martensii Karsch scorpion is an important traditional Chinese medical material that has been widely used to treat various diseases in China for over one thousand years. Our recent work showed that thermally processed Buthus
Externí odkaz:
https://doaj.org/article/5340f4367af04f2298bbb73d8a6743aa
Autor:
Zhenyu Liu, Wenhui Jiang, Cholsong Kim, Xiaoya Peng, Cong Fan, Yingliang Wu, Zhixiong Xie, Fang Peng
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7662 (2023)
Polar regions tend to support simple food webs, which are vulnerable to phage-induced gene transfer or microbial death. To further investigate phage-host interactions in polar regions and the potential linkage of phage communities between the two pol
Externí odkaz:
https://doaj.org/article/9d7c8dad2f0f4f6a94f0400e5396910a
Autor:
Chao Wang, Yuelin Li, Zi Liu, Zeyu Wang, Zihan Liu, Shuai Man, Yujing Zhang, Kai Bao, Yingliang Wu, Qi Guan, Daiying Zuo, Weige Zhang
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 549-560 (2021)
A series of 1-aryl-5-(4-arylpiperazine-1-carbonyl)-1H-tetrazols as microtubule destabilizers were designed, synthesised and evaluated for anticancer activity. Based on bioisosterism, we introduced the tetrazole moiety containing the hydrogen-bond acc
Externí odkaz:
https://doaj.org/article/1b1575218cb449939a32c6f200cd2555
Autor:
Zhixiang Tan, Zhiguo Yu, Xiaobo Xu, Lanxia Meng, Mosheng Yu, Rui Tao, Yingliang Wu, Zhanyong Zhu
Publikováno v:
Mediators of Inflammation, Vol 2022 (2022)
Scorpion peptides have good therapeutic effect on chronic ulcer of diabetic foot, but the related pharmacological mechanism has remained unclear. The different proteins and bacteria present in ulcer exudates from chronic diabetic foot patients, treat
Externí odkaz:
https://doaj.org/article/a2f1afcd991e49b88d46e067796f433c