Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Yinglei Zhai"'
Autor:
Shuo Wang, Tian Liu, Yuetong Huang, Chaoying Du, Danping Wang, Xiyan Wang, Qingzhi Lv, Zhonggui He, Yinglei Zhai, Bingjun Sun, Jin Sun
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 3, Pp 1400-1411 (2024)
The self-assembly prodrugs are usually consisted of drug modules, activation modules, and assembly modules. Keeping the balance between efficacy and safety by selecting suitable modules remains a challenge for developing prodrug nanoassemblies. This
Externí odkaz:
https://doaj.org/article/e0d547b0a3714993bbe9600f2b106fa9
Autor:
Jian Zhao, Hao Ye, Qi Lu, Kaiyuan Wang, Xiaofeng Chen, Jiaxuan Song, Helin Wang, Yutong Lu, Maosheng Cheng, Zhonggui He, Yinglei Zhai, Haotian Zhang, Jin Sun
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Melanoma is the most serious type of skin cancer, and surgery is an effective method to treat melanoma. Unfortunately, local residual micro-infiltrated tumour cells and systemic circulating tumour cells (CTCs) are significant caus
Externí odkaz:
https://doaj.org/article/a73cb54d6b43476eabbf766c31494ba5
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 1, Pp 92-106 (2022)
Nanoparticulate drug delivery systems (Nano-DDSs) have emerged as possible solution to the obstacles of anticancer drug delivery. However, the clinical outcomes and translation are restricted by several drawbacks, such as low drug loading, premature
Externí odkaz:
https://doaj.org/article/2d5f457ab456439aa9ac393985720f96
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 14, Iss 2, Pp 130-143 (2019)
Abstracts: Diabetes is one of the most prevalent diseases in the world with high-mortality and complex complications including diabetic foot ulcer (DFU). It has been reported that the difficulties in repairing the wound related to DFU has much relati
Externí odkaz:
https://doaj.org/article/432d7219553c48f59f3919d5de5eb039
Publikováno v:
Asian Journal of Pharmaceutical Sciences, Vol 9, Iss 6, Pp 330-335 (2014)
To compare pharmacokinetic behaviors of nitrendipine submicron emulsion with nitrendipine solution following intravenous administration in rats. The plasma concentrations were analyzed by ultra-performance liquid chromatography coupled with tandem ma
Externí odkaz:
https://doaj.org/article/15a41baf240e4dce81eda03513b1e221
Publikováno v:
Polymers, Vol 10, Iss 10, p 1127 (2018)
The side effects of doxorubicin (DOX) extremely limit its application in the treatment of malignant tumors. Nano-sized polymeric drugs based on the acidic microenvironment of tissular- or intra- tumor have attracted ample attention because of their p
Externí odkaz:
https://doaj.org/article/c8c25cb1b1ba4ac581d751d39da7e4c5
Publikováno v:
Polymers, Vol 9, Iss 12, p 698 (2017)
The differences in micro-environment between cancer cells and the normal ones offer the possibility to develop stimuli-responsive drug-delivery systems for overcoming the drawbacks in the clinical use of anticancer drugs, such as paclitaxel, doxorubi
Externí odkaz:
https://doaj.org/article/141b058fbae74b64896176db3e1b242a
Autor:
Danping Wang, Lingxiao Li, Hezhen Xu, Yixin Sun, Wenxiao Li, Tian Liu, Yan Li, Xianbao Shi, Zhonggui He, Yinglei Zhai, Bingjun Sun, Jin Sun
Publikováno v:
Nano Letters. 23:3549-3557
Autor:
Danping Wang, Chaoying Du, Shuo Wang, Lingxiao Li, Tian Liu, Jiaxuan Song, Zhonggui He, Yinglei Zhai, Bingjun Sun, Jin Sun
Publikováno v:
ACS Applied Materials & Interfaces. 14:51200-51211
Prodrug-based self-assembled nanoparticles combined with the merits of nanotechnology and prodrugs strategies have gradually become a research trending topic in the field of drug delivery. These prodrugs usually consist of parent drugs, connecting bo
Autor:
Jing Ye, Qinghua Li, Yushan Zhang, Qi Su, Zujian Feng, Pingsheng Huang, Chuangnian Zhang, Yinglei Zhai, Weiwei Wang
Publikováno v:
Acta Biomaterialia.