Zobrazeno 1 - 10
of 394
pro vyhledávání: '"Yingjie ZHU"'
Autor:
Yalei Wen, Hui Wang, Xiao Yang, Yingjie Zhu, Mei Li, Xiuqing Ma, Lei Huang, Rui Wan, Caishi Zhang, Shengrong Li, Hongling Jia, Qin Guo, Xiaoyun Lu, Zhengqiu Li, Xiangchun Shen, Qiushi Zhang, Lu Si, Chengqian Yin, Tongzheng Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Activating mutations in NRAS account for 15–20% of melanoma, yet effective anti-NRAS therapies are still lacking. In this study, we unveil the casein kinase 1δ (CK1δ) as an uncharacterized regulator of oncogenic NRAS mutations, specifica
Externí odkaz:
https://doaj.org/article/83e26542cf344856a8abf2d239e81390
Autor:
Manisha Jalan, Aman Sharma, Xin Pei, Nils Weinhold, Erika S. Buechelmaier, Yingjie Zhu, Sana Ahmed-Seghir, Abhirami Ratnakumar, Melody Di Bona, Niamh McDermott, Joan Gomez-Aguilar, Kyrie S. Anderson, Charlotte K. Y. Ng, Pier Selenica, Samuel F. Bakhoum, Jorge S. Reis-Filho, Nadeem Riaz, Simon N. Powell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Collisions of the transcription and replication machineries on the same DNA strand can pose a significant threat to genomic stability. These collisions occur in part due to the formation of RNA-DNA hybrids termed R-loops, in which a newly tr
Externí odkaz:
https://doaj.org/article/7cd61270c6534754a1bbd7203bce046c
Autor:
Shaolei Jiang, Bo Song, Zhongdong Liu, Shuifa Shen, Weiliang Qian, Jing Sun, Gaowei Chen, Yingjie Zhu
Publikováno v:
Neuroscience Research, Vol 205, Iss , Pp 16-26 (2024)
Although the brain can discriminate between various sweet substances, the underlying neural mechanisms of this complex behavior remain elusive. This study examines the role of the anterior paraventricular nucleus of the thalamus (aPVT) in governing s
Externí odkaz:
https://doaj.org/article/6429a7c349c248d1812cff3587e83763
Autor:
Yingjie Zhu, Xin Pei, Ardijana Novaj, Jeremy Setton, Daniel Bronder, Fatemeh Derakhshan, Pier Selenica, Niamh McDermott, Mehmet Orman, Sarina Plum, Shyamal Subramanyan, Sara H. Braverman, Biko McMillan, Sonali Sinha, Jennifer Ma, Andrea Gazzo, Atif Khan, Samuel Bakhoum, Simon N. Powell, Jorge S. Reis-Filho, Nadeem Riaz
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Pathogenic BRCA1 or BRCA2 germline mutations contribute to hereditary breast, ovarian, prostate, and pancreatic cancer. Paradoxically, bi-allelic inactivation of BRCA1 or BRCA2 (bBRCA1/2) is embryonically lethal and decreases cell
Externí odkaz:
https://doaj.org/article/a99e307f304a411b854e096a6e780f20
Autor:
Jing Sun, Xiaofei Deng, Lin Zhu, Jianbang Lin, Gaowei Chen, Yong Tang, Shanshan Lu, Zhonghua Lu, Zhiqiang Meng, Yuantao Li, Yingjie Zhu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract The potential long-term effects of anesthesia on cognitive development, especially in neonates and infants, have raised concerns. However, our understanding of its underlying mechanisms and effective treatments is still limited. In this stud
Externí odkaz:
https://doaj.org/article/47b589dfe7ff414993a5313dbfe7bd90
Publikováno v:
Ecology and Evolution, Vol 14, Iss 11, Pp n/a-n/a (2024)
ABSTRACT Increasing levels of UV‐B radiation caused by the greenhouse effect has become an emerging threat to crop health and yield. The glutathione (GSH) metabolic pathway is generally involved in plant stress responses through scavenging accumula
Externí odkaz:
https://doaj.org/article/657550353c5d42c49a9a2f94822d49ef
Publikováno v:
BMC Public Health, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Frailty not only affects disease survival but also impacts the long-term function and quality life of all adults diagnosed with and/or treated for cancer.The American Heart Association has introduced Life’s Essential 8 (LE8) as
Externí odkaz:
https://doaj.org/article/f3d0dae8a7b64f0fbc3a9cd31fd58710
Publikováno v:
南方能源建设, Vol 11, Iss 1, Pp 185-195 (2024)
[Introduction] With the increasing frequency of extreme weather in China's coastal areas, typhoon disasters pose a great threat to coastal power grids, in order to improve the lines wind protection ability, the design of coastal strong wind area line
Externí odkaz:
https://doaj.org/article/cb3e1a8846454e48b82d3de9b63e8269
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundMalnutrition is strongly correlated with worsened treatment outcomes, reduced standard of living, and heightened mortality rates among individuals with cancer. Our research explores how the Geriatric Nutritional Risk Index (GNRI), a measure
Externí odkaz:
https://doaj.org/article/b3eeeb3dd32a4705bf3f6f689edfcefb
Publikováno v:
Journal of Functional Foods, Vol 116, Iss , Pp 106200- (2024)
Background: Metabolic syndrome (MetS) is a pathological condition. Oxidative stress is intricately linked to MetS, and may be reflected by composite dietary antioxidant index (CDAI). We aimed to explore the association between CDAI and MetS. Methods:
Externí odkaz:
https://doaj.org/article/a1434f5b23a142599565f6569d3a79a4