Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Yingjia, Yao"'
Autor:
Chunge Zhong, Wen-Jie Jiang, Yingjia Yao, Zexu Li, You Li, Shengnan Wang, Xiaofeng Wang, Wenjuan Zhu, Siqi Wu, Jing Wang, Shuangshuang Fan, Shixin Ma, Yeshu Liu, Han Zhang, Wenchang Zhao, Lu Zhao, Yi Feng, Zihan Li, Ruifang Guo, Li Yu, Fengyun Pei, Jun Hu, Xingzhi Feng, Zihuan Yang, Zhengjia Yang, Xueying Yang, Yue Hou, Danni Zhang, Dake Xu, Ren Sheng, Yihao Li, Lijun Liu, Hua-Jun Wu, Jun Huang, Teng Fei
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Resistance to chemotherapy has been a major hurdle that limits therapeutic benefits for many types of cancer. Here we systematically identify genetic drivers underlying chemoresistance by performing 30 genome-scale CRISPR knockout screens fo
Externí odkaz:
https://doaj.org/article/e05d9e0e44d3454b9b83a793d45bfd7a
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100653- (2021)
Summary: Drug repositioning represents a cost- and time-efficient strategy for drug development. Artificial intelligence-based algorithms have been applied in drug repositioning by predicting drug-target interactions in an efficient and high throughp
Externí odkaz:
https://doaj.org/article/e205aac446894f3b9a2fa19040fe8d90
Autor:
Zexu Li, Yingjia Yao, Xiaolong Cheng, Qing Chen, Wenchang Zhao, Shixin Ma, Zihan Li, Hu Zhou, Wei Li, Teng Fei
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102148- (2021)
Summary: RNA viruses are responsible for many zoonotic diseases that post great challenges for public health. Effective therapeutics against these viral infections remain limited. Here, we deployed a computational framework for host-based drug reposi
Externí odkaz:
https://doaj.org/article/dc286646403648469a63c4fb769d7b4f
Publikováno v:
Life Sciences. 318:121418
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::291a2ef1659e129c14250c3ed20091f4
https://doi.org/10.1016/j.lfs.2023.121418
https://doi.org/10.1016/j.lfs.2023.121418
Autor:
Zexu Li, Zihan Li, Xiaolong Cheng, Xiaofeng Wang, Shixin Ma, Shengnan Wang, Zhiyan Lu, Han Zhang, Wenchang Zhao, Zhisong Chen, Yingjia Yao, Lumen Chao, Wei Li, Teng Fei
SUMMARYCRISPR-Cas13 systems have been adapted as versatile toolkits for RNA-related applications. Here we systematically evaluate the performance of several popular Cas13 family effectors (Cas13a, Cas13b and Cas13d) under lentiviral vectors and revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee4dcccd28f87b64f25257a41ff7945f
https://doi.org/10.1101/2022.05.14.491940
https://doi.org/10.1101/2022.05.14.491940
Autor:
Yuhui Yan, Liang Kong, Yang Xia, Wenbo Liang, Litong Wang, Jie Song, Yingjia Yao, Ying Lin, Jingxian Yang
Publikováno v:
Brain, Behavior, and Immunity. 106:322
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1cdfc5f75f75569c183fa6f88144814
https://doi.org/10.1016/j.bbi.2022.08.002
https://doi.org/10.1016/j.bbi.2022.08.002
Publikováno v:
Life Sciences. 305:120747
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5de0715b63763c33f79dd8dd0da5c7d
https://doi.org/10.1016/j.lfs.2022.120747
https://doi.org/10.1016/j.lfs.2022.120747
Publikováno v:
Life Sciences. 225:117-131
Aim Alzheimer's disease (AD) is a slowly progressing neurodegenerative disorder that attributed to the increase of amyloid precursor protein (APP). Recently, evidence indicates that microRNA alterations are involved in the development of AD. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcac85c0ce0515ecdabb058def186d0a
https://doi.org/10.1016/j.lfs.2019.04.004
https://doi.org/10.1016/j.lfs.2019.04.004
Publikováno v:
IEEE Internet of Things Journal. 6:1363-1374
Recently, development of wearable and Internet of Things (IoT) technologies enables the real-time and continuous individual electrocardiogram (ECG) monitoring. In this paper, we develop a novel IoT-based wearable 12-lead ECG SmartVest system for earl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33a6626f04228ebb9fe04f00c7be3744
https://doi.org/10.1109/jiot.2018.2844090
https://doi.org/10.1109/jiot.2018.2844090
Publikováno v:
Life Sciences. 217:16-24
Aim Alzheimer's disease (AD), a neurodegenerative disease, was characterized by the loss of memory and progressive cognitive deterioration. Up to now, there has no effective drugs to cure or delay the state of illness. Increasing evidence indicates t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8745a4b0227d738e22cc7fcb29dae044
https://doi.org/10.1016/j.lfs.2018.11.038
https://doi.org/10.1016/j.lfs.2018.11.038