Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Yinghui Jane Huang"'
Autor:
Omar Khan, Sasikanth Manne, E John Wherry, Josephine R Giles, Amy E Baxter, Shin Foong Ngiow, Yinghui Jane Huang, Simone L Park, Jennifer E Wu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/dda59d50efd34eaf8e85bec76f4672ea
Autor:
Sokratis A. Apostolidis, Amrita Sarkar, Heather M. Giannini, Rishi R. Goel, Divij Mathew, Aae Suzuki, Amy E. Baxter, Allison R. Greenplate, Cécile Alanio, Mohamed Abdel-Hakeem, Derek A. Oldridge, Josephine R. Giles, Jennifer E. Wu, Zeyu Chen, Yinghui Jane Huang, Jonathan Belman, Ajinkya Pattekar, Sasikanth Manne, Oliva Kuthuru, Jeanette Dougherty, Brittany Weiderhold, Ariel R. Weisman, Caroline A. G. Ittner, Sigrid Gouma, Debora Dunbar, Ian Frank, Alexander C. Huang, Laura A. Vella, The UPenn COVID Processing Unit, John P. Reilly, Scott E. Hensley, Lubica Rauova, Liang Zhao, Nuala J. Meyer, Mortimer Poncz, Charles S. Abrams, E. John Wherry, Sharon Adamski, Zahidul Alam, Mary M. Addison, Katelyn T. Byrne, Aditi Chandra, Hélène C. Descamps, Nicholas Han, Yaroslav Kaminskiy, Shane C. Kammerman, Justin Kim, Jacob T. Hamilton, Nune Markosyan, Julia Han Noll, Dalia K. Omran, Eric Perkey, Elizabeth M. Prager, Dana Pueschl, Austin Rennels, Jennifer B. Shah, Jake S. Shilan, Nils Wilhausen, Ashley N. Vanderbeck
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Patients with COVID-19 present with a wide variety of clinical manifestations. Thromboembolic events constitute a significant cause of morbidity and mortality in patients infected with SARS-CoV-2. Severe COVID-19 has been associated with hyperinflamm
Externí odkaz:
https://doaj.org/article/f380b6f884834140a346b9249d88cbb6
Autor:
Josephine R. Giles, Shin Foong Ngiow, Sasikanth Manne, Amy E. Baxter, Omar Khan, Ping Wang, Ryan Staupe, Mohamed S. Abdel-Hakeem, Hua Huang, Divij Mathew, Mark M. Painter, Jennifer E. Wu, Yinghui Jane Huang, Rishi R. Goel, Patrick K. Yan, Giorgos C. Karakousis, Xiaowei Xu, Tara C. Mitchell, Alexander C. Huang, E. John Wherry
Publikováno v:
Nature Immunology. 23:1600-1613
Autor:
Josephine R. Giles, Shin Foong Ngiow, Sasikanth Manne, Amy E. Baxter, Omar Khan, Ping Wang, Ryan Staupe, Mohamed S. Abdel-Hakeem, Hua Huang, Divij Mathew, Mark M. Painter, Jennifer E. Wu, Yinghui Jane Huang, Rishi Goel, E. John Wherry
Naïve CD8 T cells can differentiate into effector (TEFF), memory (TMEM), or exhausted (TEX) CD8 T cells. These developmental pathways are associated with distinct transcriptional and epigenetic changes that endow cells with different functional capa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c322ce5cfd2736b15eb1ae9bcae8808b
https://doi.org/10.1101/2022.03.27.485974
https://doi.org/10.1101/2022.03.27.485974
Autor:
Jeanette Dougherty, Sasikanth Manne, Amy E. Baxter, Josephine R. Giles, Yinghui Jane Huang, Ajinkya Pattekar, Oliva Kuthuru, Jennifer E. Wu, Aae Suzuki, Nuala J. Meyer, Debora Dunbar, Zeyu Chen, Alexander C. Huang, Ariel R. Weisman, Allison R. Greenplate, Mortimer Poncz, Charles S. Abrams, Ian Frank, Liang Zhao, Caroline A. G. Ittner, Mohamed S. Abdel-Hakeem, Amrita Sarkar, Rishi R. Goel, Sigrid Gouma, Divij Mathew, Sokratis A. Apostolidis, John P. Reilly, Derek A. Oldridge, Cécile Alanio, Scott E. Hensley, Laura A. Vella, E. John Wherry, Heather M. Giannini, Lubica Rauova, Brittany Weiderhold
Publikováno v:
bioRxiv
article-version (status) pre
article-version (number) 1
article-version (status) pre
article-version (number) 1
Patients with COVID-19 present with a wide variety of clinical manifestations. Thromboembolic events constitute a significant cause of morbidity and mortality in patients infected with SARS-CoV-2. Severe COVID-19 has been associated with hyperinflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63b8c501dfe82e024f027c6827feee13
https://doi.org/10.1101/2021.05.01.442279
https://doi.org/10.1101/2021.05.01.442279
Autor:
Eileen C. Goodwin, Peyton Conrey, Divij Mathew, E. John Wherry, Heather M. Giannini, Cécile Alanio, Kevin O McNerney, Leticia Kuri-Cervantes, Marcus J. Bolton, Josephine R. Giles, Sigrid Gouma, Samir Sayed, Laura A. Vella, Jessica H. Lee, Julie Chase, Oliva Kuthuru, Claudia P. Arevalo, Scott E. Hensley, Zeyu Chen, Chakkapong Burudpakdee, Sarah E. Henrickson, Derek A. Oldridge, Amy E. Baxter, David T. Teachey, Kurt D'Andrea, Andre Ramos, Caroline Diorio, Hamid Bassiri, Nuala J. Meyer, Elizabeth M. Anderson, M. Betina Pampena, Edward M. Behrens, Yinghui Jane Huang, Sokratis A. Apostolidis, Madison E. Weirick, Jennifer E. Wu, Alexander C. Huang, Cristina Jasen, Michael R. Betts
Publikováno v:
Science Immunology
medRxiv
medRxiv
MIS-C is defined by lymphocyte activation, including elevated plasmablast frequencies and marked activation of CX3CR1+ CD8+ T cells.
Pediatric COVID-19 following SARS-CoV-2 infection is associated with fewer hospitalizations and often milder dis
Pediatric COVID-19 following SARS-CoV-2 infection is associated with fewer hospitalizations and often milder dis
Autor:
Ariel R. Weisman, Ajinkya Pattekar, Fang Chen, Caroline A. G. Ittner, Cécile Alanio, Sasikanth Manne, Zeyu Chen, E. John Wherry, Holly Ramage, M. Betina Pampena, Scott E. Hensley, Kito Nzingha, Justin Kim, Amy E. Baxter, Jeanette Dougherty, Divij Mathew, Michael R. Betts, Allison R. Greenplate, Claudia P. Arevalo, Yinghui Jane Huang, Leticia Kuri-Cervantes, Josephine R. Giles, Derek A. Oldridge, Nuala J. Meyer, Jennifer E. Wu, Marcus J. Bolton, Laura A. Vella, John P. Reilly, Alexander C. Huang, Elizabeth M. Anderson, Eileen C. Goodwin, Madison E. Weirick, Simon F. Lacey, Sokratis A. Apostolidis, Sara Cherry, Kurt D'Andrea, Nicholas Han, Sigrid Gouma, Oliva Kuthuru
Publikováno v:
Science
Science (New York, N.y.)
Science (New York, N.y.)
Immune profiling of COVID-19 patients Coronavirus disease 2019 (COVID-19) has affected millions of people globally, yet how the human immune system responds to and influences COVID-19 severity remains unclear. Mathew et al. present a comprehensive at
Autor:
Jean-Christophe Beltra, Sasikanth Manne, Mohamed S Abdel-Hakeem, Kito Nzingha, Zhen Zhang, Hua Huang, Makoto Kurachi, Yuki Muroyama, Yinghui Jane Huang, Leon L Su, Lora Picton, Helene Decaluwe, Alexander C Huang, Shelley L Berger, Christopher K Garcia, E. John Wherry
Publikováno v:
The Journal of Immunology. 206:14.13-14.13
Exhaustion gradually establishes in chronically stimulated CD8s and this process is not reverted by current therapeutic approaches due to establishment of a stable epigenetic program. Recent advances have informed on the developmental process of exha
Autor:
Jean-Christophe, Beltra, Sasikanth, Manne, Mohamed S, Abdel-Hakeem, Makoto, Kurachi, Josephine R, Giles, Zeyu, Chen, Valentina, Casella, Shin Foong, Ngiow, Omar, Khan, Yinghui Jane, Huang, Patrick, Yan, Kito, Nzingha, Wei, Xu, Ravi K, Amaravadi, Xiaowei, Xu, Giorgos C, Karakousis, Tara C, Mitchell, Lynn M, Schuchter, Alexander C, Huang, E John, Wherry
Publikováno v:
Immunity. 52(5)
CD8
Autor:
Jean-Christophe Beltra, Sasikanth Manne, Mohamed S Abdel Hakeem, Makoto Kurachi, Josephine R Giles, Zeyu Chen, Valentina Casella, Shin Ngiow, Omar Khan, Yinghui Jane Huang, Patrick Yan, Kito Nzingha, Alexander C. Huang, E. John Wherry
Publikováno v:
The Journal of Immunology. 204:77.16-77.16
Exhausted CD8 T cells (TEX) are essential during chronic viral infections and cancer. Two TEX subpopulations including a progenitor and a more terminally exhausted subset cooperate to maintain an active immune response during antigen persistence. How