Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Yinghua Tang"'
Association of rs2241766 and rs1501299 polymorphisms in the adiponectin gene with metabolic syndrome
Publikováno v:
Immunity, Inflammation and Disease, Vol 12, Iss 9, Pp n/a-n/a (2024)
Abstract Objective To investigate the influence of adiponectin (APN) rs2241766 and rs1501299 polymorphisms on adiponectin levels and their association with metabolic syndrome (MetS). Methods Analyzed two polymorphisms (rs2241766 and rs1501299) of the
Externí odkaz:
https://doaj.org/article/08493bfe058b4314acee121761d529e5
Autor:
Yinghua Tang, Mehrnoosh Ebadi, Junying Lei, Zehua Feng, Shahab Fakhari, Peipei Wu, Mark D. Smith, Maria P. Limberis, Roland Kolbeck, Katherine J. Excoffon, Ziying Yan, John F. Engelhardt
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101244- (2024)
The dosing interval for effective recombinant adeno-associated virus (rAAV)-mediated gene therapy of cystic fibrosis lung disease remains unknown. Here, we assessed the durability of rAAV2.5T-fCFTRΔR-mediated transgene expression and neutralizing an
Externí odkaz:
https://doaj.org/article/27a6b1d9b32d4d5fbd5e3361073b18ed
Autor:
Yinghua Tang, Shahab Fakhari, Eric D. Huntemann, Zehua Feng, Peipei Wu, William Y. Feng, Junying Lei, Feng Yuan, Katherine J. Excoffon, Kai Wang, Maria P. Limberis, Roland Kolbeck, Ziying Yan, John F. Engelhardt
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 70-80 (2023)
The efficacy of redosing the recombinant adeno-associated virus (rAAV) vector rAAV2.5T to ferret lung is limited by AAV neutralizing antibody (NAb) responses. While immunosuppression strategies have allowed for systemic rAAV repeat dosing, their util
Externí odkaz:
https://doaj.org/article/1cbaa351bc964c2ea2b39626805cbbeb
Autor:
Lianli Yin, Yinghua Tang
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Ferroptosis genes have recently been reported to be involved in regulating the development of cancer, but their potential role in breast cancer (BRCA) is not fully understood. The purpose of this study is to systematically study the mechanis
Externí odkaz:
https://doaj.org/article/81a00f0640d44fed997b55f51543f3b4
Autor:
Yinghua Tang, Ziying Yan, Shen Lin, Eric D. Huntemann, Zehua Feng, Soo-Yeun Park, Xingshen Sun, Eric Yuen, John F. Engelhardt
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 19, Iss , Pp 186-200 (2020)
Readministration of recombinant adeno-associated virus (rAAV) may be necessary to treat cystic fibrosis (CF) lung disease using gene therapy. However, little is known about rAAV-mediated immune responses in the lung. Here, we demonstrate the suitabil
Externí odkaz:
https://doaj.org/article/d7466e4db45d4d0aaaee025e209b82d9
Publikováno v:
Molecular Cytogenetics, Vol 13, Iss 1, Pp 1-7 (2020)
Abstract Objective To investigate the clinical value of noninvasive prenatal testing (NIPT) for fetal chromosomal deletion, duplication, and sex chromosome abnormalities. Methods The study included 6239 pregnant women with singletons in the first and
Externí odkaz:
https://doaj.org/article/6fa6a446d504454c8e51454d861b6af6
Autor:
Xiaoxi He, Si Chen, Yinghua Tang, Xiaomin Zhao, Liting Yan, Lihong Wu, Zhicong Wu, Weijia Liu, Xinming Chen, Xinhong Wang
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
ObjectivesTo investigate the role of hepatocyte growth factor (HGF)/c-Met signaling in oral malignant transformation.MethodsWe used immunohistochemistry to investigate HGF and c-Met expression in 53 oral squamous cell carcinoma (OSCC) specimens and 2
Externí odkaz:
https://doaj.org/article/62e30e51fffe43bb9871407a7017f717
Autor:
Peipei Wu, Jihu Lu, Xuehua Zhang, Mei Mei, Lei Feng, Daxin Peng, Jibo Hou, Sang-Moo Kang, Xiufan Liu, Yinghua Tang
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The H5 subtype highly pathogenic avian influenza (HPAI) virus is one of the greatest threats to global poultry industry. To develop broadly protective H5 subunit vaccine, a recombinant consensus HA sequence (rHA) was constructed and expressed in viru
Externí odkaz:
https://doaj.org/article/6d7234584ce441cd8d286c207a175903
Autor:
Peipei Wu, Jihu Lu, Lei Feng, Hongzhuan Wu, Xuehua Zhang, Mei Mei, Jibo Hou, Xiufan Liu, Yinghua Tang
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
We previously described that immunopotentiators, CVCVA5, increased the efficacy of H5 and H9 subtype avian influenza vaccines in chickens, ducks, and geese. In this study, we further investigated the effects of the CVCVA5 for improving the efficacy o
Externí odkaz:
https://doaj.org/article/1b63292032a5407dab57a460b37c5aff
Autor:
Jihu Lu, Peipei Wu, Xuehua Zhang, Lei Feng, Bin Dong, Xuan Chu, Xiufan Liu, Daxin Peng, Yuan Liu, Huailiang Ma, Jibo Hou, Yinghua Tang
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156573 (2016)
Combination of CVCVA5 adjuvant and commercial avian influenza (AI) vaccine has been previously demonstrated to provide good protection against different AI viruses in chickens. In this study, we further investigated the protective immunity of CVCVA5-
Externí odkaz:
https://doaj.org/article/3e82f9687e2a4ed3b339b8856a32857d