Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yinghan Zhuang"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
The dopaminergic system is susceptible to dysfunction in numerous neurological diseases, including Parkinson’s disease (PD). In addition to motor symptoms, some PD patients may experience non-motor symptoms, including cognitive and memory deficits.
Externí odkaz:
https://doaj.org/article/d14320a61dc248b5a1a592f702f96c8f
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
The hippocampal formation plays a vital role in memory formation and takes part in the control of the default neuronal network activity of the brain. It also represents an important structure to analyze drug-induced effects on subregion-specific sync
Externí odkaz:
https://doaj.org/article/abd69f2bdc734b45aafa816a14f88370
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 10 (2016)
The elongation factor 2 kinase (eEF2K), likewise known as CaMKIII, has been demonstrated to be involved in antidepressant responses of NMDA receptor antagonists. Even so, it remains open whether direct inhibition of eEF2K without altering up-flow or
Externí odkaz:
https://doaj.org/article/c34efb107028428f9db7830e4fb4db14
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
The hippocampal formation plays a vital role in memory formation and takes part in the control of the default neuronal network activity of the brain. It also represents an important structure to analyze drug-induced effects on subregion-specific sync
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e3a7a3ca06e5ee3ee5b5eda9f1ae14
https://www.frontiersin.org/article/10.3389/fncel.2020.00024/full
https://www.frontiersin.org/article/10.3389/fncel.2020.00024/full
Publikováno v:
Neuropharmacology. 133:354-365
Posttranslational modification and degradation of proteins by the ubiquitin-proteasome system (UPS) is crucial to synaptic transmission. It is well established that 19S proteasome associated deubiquitinases (DUBs) reverse the process of ubiquitinatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::243255d578303cf5a9d21b39eda1482c
https://doi.org/10.1016/j.neuropharm.2018.01.043
https://doi.org/10.1016/j.neuropharm.2018.01.043
Publikováno v:
Neural Regeneration Research, Vol 13, Iss 4, Pp 717-726 (2018)
Neural Regeneration Research
Neural Regeneration Research
Parkinson's disease is a progressive neurological disease characterized by the degeneration of dopaminergic neurons in the substantia nigra. A highly similar pattern of neurodegeneration can be induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a11a64463ec45b0c093b92a5f7e64459
http://www.nrronline.org/article.asp?issn=1673-5374
http://www.nrronline.org/article.asp?issn=1673-5374
Autor:
Man Wang, Pietro Paolo Sanna, Yinghan Zhuang, Di Yun, Thomas Behnisch, Dongxue Li, Vez Repunte-Canonigo
Publikováno v:
Neurobiology of Learning and Memory. 138:121-134
While the brain-derived neurotrophic factor (BDNF) gene and its multiple transcripts have been recognized as a key factor for learning, but the specific involvement of BDNF translated from BDNF transcripts with short-3' untranslated region (short 3'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4400dcb89a3a51f10fdd06b7ee37b095
https://doi.org/10.1016/j.nlm.2016.07.004
https://doi.org/10.1016/j.nlm.2016.07.004
Autor:
Dongping Huang, Haiyun Suo, Jing Xu, Xiaoqi Hong, Guoqi Zhu, Mei Yu, YingHan Zhuang, Yufang Huang, Zhejin Sheng, MinJuan Bian, Houyan Song, Fang Huang, Jian Fei, Jie Liu, Pan Wang, Thomas Behnisch
Publikováno v:
Human Molecular Genetics. 23:1056-1072
Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by a severe decline of memory performance. A widely studied AD mouse model is the APPswe/PSEN1ΔE9 (APP/PS1) strain, as mice exhibit amyloid plaques as well as impaire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49454579daaa9a6ffa43cc59d49b1a54
https://doi.org/10.1093/hmg/ddt501
https://doi.org/10.1093/hmg/ddt501
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 9 (2015)
Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience
The neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) induces Parkinson's disease-like symptoms following administration to mice, monkeys, and humans. A common view is that MPTP is metabolized to 1-methyl-4-phenylpyridinium ion (MPP(+))
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f4f6e4f86dd37510ee2d6977166fb1
http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00299/full
http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00299/full
Publikováno v:
Journal of neurochemistry. 122(3)
Parkinson's disease (PD)-like symptoms and cognitive deficits are inducible by 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP). Since cognitive abilities, including memory formations rely also on hippocampus, we set out to clarify the effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db5a3e4b6df99a0a056084b8ddd2aa86
https://pubmed.ncbi.nlm.nih.gov/22651101
https://pubmed.ncbi.nlm.nih.gov/22651101