Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Yingfu Lin"'
Autor:
Babak Mahjour, Rui Zhang, Yuning Shen, Andrew McGrath, Ruheng Zhao, Osama G. Mohamed, Yingfu Lin, Zirong Zhang, James L. Douthwaite, Ashootosh Tripathi, Tim Cernak
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract High-throughput experimentation (HTE) is an increasingly important tool in reaction discovery. While the hardware for running HTE in the chemical laboratory has evolved significantly in recent years, there remains a need for software solutio
Externí odkaz:
https://doaj.org/article/c7f5cfb9bc6d4d6984f573713ac5573b
Autor:
Yingfu Lin, Zirong Zhang, Babak Mahjour, Di Wang, Rui Zhang, Eunjae Shim, Andrew McGrath, Yuning Shen, Nadia Brugger, Rachel Turnbull, Sarah Trice, Shashi Jasty, Tim Cernak
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
COVID-19 has exposed the fragility of supply chains, particularly for goods that are essential or may suddenly become essential, such as repurposed pharmaceuticals. Here the authors develop a methodology to provide routes to pharmaceutical targets th
Externí odkaz:
https://doaj.org/article/9762a8439c8b44009a50a6e39bbfbc7a
Autor:
Yingfu Lin, Zirong Zhang, Babak Mahjour, Di Wang, Rui Zhang, Eunjae Shim, Andrew McGrath, Yuning Shen, Nadia Brugger, Rachel Turnbull, Sarah Trice, Shashi Jasty, Tim Cernak
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/e8ff2b3c87494e3d9cae36aa79ab06d7
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185783 (2017)
Sexually transmitted Chlamydia trachomatis is an extremely common infection and often leads to serious complications including infertility and pelvic inflammatory syndrome. Several broad-spectrum antibiotics are currently used to treat C. trachomatis
Externí odkaz:
https://doaj.org/article/9c386ae4ebd14286abf4e4e06dd0ccb9
Publikováno v:
Science. 2/3/2023, Vol. 379 Issue 6631, p453-457. 5p. 4 Diagrams.
Autor:
Babak Mahjour, Rui Zhang, Yuning Shen, Andrew McGrath, Ruheng Zhao, Osama G. Mohamed, Yingfu Lin, Zirong Zhang, James L. Douthwaite, Ashootosh Tripathi, Tim Cernak
High throughput experimentation (HTE) is an increasingly important tool in reaction discovery. While the hardware for running HTE in the chemical laboratory has evolved significantly in recent years, there remains a need for software solutions to nav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68e2279ab135e1b31205ca87e4503477
https://doi.org/10.26434/chemrxiv-2022-hcnng
https://doi.org/10.26434/chemrxiv-2022-hcnng
Autor:
Andrew McGrath, Sarah Trice, Zirong Zhang, Eunjae Shim, Tim Cernak, Rui Zhang, Babak Mahjour, Rachel Turnbull, Yingfu Lin, Yuning Shen, Nadia Brugger, Di Wang, Shashi Jasty
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
The global disruption caused by the 2020 coronavirus pandemic stressed the supply chain of many products, including pharmaceuticals. Multiple drug repurposing studies for COVID-19 are now underway. If a winning therapeutic emerges, it is unlikely tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8240cdda30a6bdbfa37e63e3c7c66708
https://doi.org/10.1038/s41467-021-27547-3
https://doi.org/10.1038/s41467-021-27547-3
Autor:
Tim Cernak, Sarah Trice, Shashi Jasty, Rachel Turnbull, Nadia Brugger, Yuning Shen, Andrew McGrath, Eunjae Shim, rui zhang, di wang, babak mahjour, Zirong Zhang, Yingfu Lin
Supply chains become stressed when demand for essential products increases rapidly in times of crisis. This year, the scourge of coronavirus highlighted the fragility of diverse supply chains, affecting the world’s pipeline of hand sanitizer, 1 toi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::836e7e0b688695c8a56660a7d8e1f1e1
https://doi.org/10.26434/chemrxiv.12765410
https://doi.org/10.26434/chemrxiv.12765410
Autor:
Anuj Kunadia, Rachael W. Karugu, Mathew J. Vetticatt, Khalil A. Abboud, Ion Ghiviriga, Anirudra Paul, Yingfu Lin, William J Hirschi, Jennifer S. Hirschi, Daniel Seidel
Publikováno v:
J Am Chem Soc
β-Amino esters are obtained with high levels of enantioselectivity via the conjugate addition of cyclic amines to unactivated α,β-unsaturated esters. A related strategy enables the kinetic resolution of racemic cyclic 2-arylamines, using benzyl ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17cfcd0b924550b208c718a40b7f0462
https://pubmed.ncbi.nlm.nih.gov/32118419
https://pubmed.ncbi.nlm.nih.gov/32118419
Publikováno v:
Angewandte Chemie International Edition. 56:15353-15357
The catalytic enantioselective synthesis of isoindolinones was achieved through the condensation of 2-acyl-benzaldehydes and anilines. In the presence of 1 mol % of a chiral phosphoric acid catalyst, reactions reach completion within 10 min and provi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2017cfe4e7b0d451f8201122cbad2ed3
https://doi.org/10.1002/anie.201709182
https://doi.org/10.1002/anie.201709182