Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Yingfang He"'
Autor:
Jie Wang, Yingfang He, Xing Chen, Lin Huang, Junpeng Li, Zhiwen You, Qi Huang, Shuhua Ren, Kun He, Roger Schibli, Linjing Mu, Yihui Guan, Qihao Guo, Jun Zhao, Fang Xie
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Metabotropic glutamate receptor 5 (mGluR5) is involved in regulating integrative brain function and synaptic transmission. Aberrant mGluR5 signaling and relevant synaptic failure play a key role in the initial pathophysiological m
Externí odkaz:
https://doaj.org/article/3a9dfe62d12145639ac45c3fb9d29f84
Autor:
Adrienne Müller Herde, Silvan D. Boss, Yingfang He, Roger Schibli, Linjing Mu, Simon M. Ametamey
Publikováno v:
Pharmaceuticals, Vol 11, Iss 3, p 83 (2018)
Several studies showed that [11C]ABP688 binding is altered following drug-induced perturbation of glutamate levels in brains of humans, non-human primates and rats. We evaluated whether the fluorinated derivative [18F]PSS232 can be used to assess met
Externí odkaz:
https://doaj.org/article/0e385519f65c4a08ac07b2023507374c
Autor:
Aebia, Johannes, Atza, Kenneth, Ametamey, Simon M., Benza, Jörg, Blaising, Julie, Butini, Stefania, Campiani, Giuseppe, Carreira, Erick M., Collin, Ludovic, de Lago, Eva, Gazzi, Thais, Gertsch, Jürg, Gobbi, Luca, Guba, Wolfgang, Fernández-Ruize, Javier, Fingerle, Jürgen, Haider, Ahmed, Yingfang He, Heitman, Laura H., Honer, Michael
Publikováno v:
Chimia; 2024, Vol. 78 Issue 7/8, p499-512, 14p
Publikováno v:
International Polymer Processing. 37:93-105
The amphiphilic copolymer polyacrylonitrile-co-poly(hydroxyethyl methacrylate) (PAN-co-PHEMA) was readily blended with polyacrylonitrile (PAN) to fabricate a flat-sheet blending membrane through non-solvent induced phase separation (NIPS). In the mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b04d616aefbc8f2aab5777835b34cf97
https://doi.org/10.1515/ipp-2021-4175
https://doi.org/10.1515/ipp-2021-4175
Autor:
Yingfang He, Luca C. Gobbi, Adrienne Müller Herde, Didier Rombach, Martin Ritter, Bernd Kuhn, Matthias B. Wittwer, Dominik Heer, Benoit Hornsperger, Charles Bell, Fionn O'Hara, Jörg Benz, Michael Honer, Claudia Keller, Ludovic Collin, Hans Richter, Roger Schibli, Uwe Grether, Linjing Mu
Publikováno v:
Nuclear Medicine and Biology, 108-109
Monoacylglycerol lipase (MAGL) is a serine hydrolase that plays an important role in the endocannabinoid degradation in the brain. It has recently emerged as a promising therapeutic target in the treatment of neuroinflammatory and neurodegenerative d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce52a586caa948df1c940c2253b3a130
https://hdl.handle.net/20.500.11850/536205
https://hdl.handle.net/20.500.11850/536205
Autor:
Hongmei Jia, Yingfang He, Shu-fei Lin, Jim Ropchan, Anupama Shirali, Evan Baum, Yiyun Huang, Michael Kapinos, Zhengxin Cai, Hong Gao, Daniel Holden, Songye Li
Publikováno v:
ACS Chemical Neuroscience. 11:1673-1681
We report a convenient radiosynthesis and the first positron emission tomography (PET) imaging evaluation of [18F]FBFP as a potent sigma-1 (σ1) receptor radioligand with advantageous characteristics. [18F]FBFP was synthesized in one step from an iod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34d47c9efe3c9f8819d722ce0cbaf6c8
https://doi.org/10.1021/acschemneuro.0c00171
https://doi.org/10.1021/acschemneuro.0c00171
Autor:
Yingfang He, Matthias Schild, Uwe Grether, Jörg Benz, Lea Leibrock, Dominik Heer, Andreas Topp, Ludovic Collin, Bernd Kuhn, Matthias Wittwer, Claudia Keller, Luca C. Gobbi, Roger Schibli, Linjing Mu
Publikováno v:
Journal of medicinal chemistry. 65(3)
Monoacylglycerol lipase (MAGL) is one of the key enzymes in the endocannabinoid system. Inhibition of MAGL has been proposed as an attractive approach for the treatment of various diseases. In this study, we designed and successfully synthesized two
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b1e37d69702e46d34439c6245badddd
https://pubmed.ncbi.nlm.nih.gov/35089028
https://pubmed.ncbi.nlm.nih.gov/35089028
Publikováno v:
Journal of Coatings Technology and Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc0d8f215168083ab7a8e5cf944e448b
https://doi.org/10.1007/s11998-021-00574-x
https://doi.org/10.1007/s11998-021-00574-x
Autor:
Yingfang He, Uwe Grether, Marco F. Taddio, Carla Meier, Claudia Keller, Martin R. Edelmann, Michael Honer, Sylwia Huber, Matthias B. Wittwer, Dominik Heer, Hans Richter, Ludovic Collin, Melanie N. Hug, Manuel Hilbert, Annemarieke G.J. Postmus, Anna Floor Stevens, Mario van der Stelt, Stefanie D. Krämer, Roger Schibli, Linjing Mu, Luca C. Gobbi
Publikováno v:
European Journal of Medicinal Chemistry, 243:114750. ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER
European Journal of Medicinal Chemistry, 243
European Journal of Medicinal Chemistry, 243
Monoacylglycerol lipase (MAGL) is a gatekeeper in regulating endocannabinoid signaling and has gained substantial attention as a therapeutic target for neurological disorders. We recently discovered a morpholin-3-one derivative as a novel scaffold fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3c55a40e57837b88082305c6a4d833
https://doi.org/10.1016/j.ejmech.2022.114750
https://doi.org/10.1016/j.ejmech.2022.114750
Autor:
Yingfang He, Uwe Grether, Marco Taddio, Claudia Keller, Michael Honer, Sywia Huber, Martin Edelmann, Stefanie Krämer, Roger Schibli, Luca Gobbi, Linjing Mu
Publikováno v:
Nuclear Medicine and Biology. :S5-S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5a7f094ff6baba65c0a6b11316312f3
https://doi.org/10.1016/s0969-8051(22)00062-2
https://doi.org/10.1016/s0969-8051(22)00062-2