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Akademický článek

Advances in the study of nicotinamide adenine dinucleotide phosphate oxidase in myocardial remodeling

Autor: Runran Miao, Libo Wang, Zhigang Chen, Shiqi Ge, Li Li, Kai Zhang, Yingen Chen, Wenjing Guo, Xulei Duan, Mingyang Zhu, Guoan Zhao, Fei Lin

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 9 (2022)

Myocardial remodeling is a key pathophysiological basis of heart failure, which seriously threatens human health and causes a severe economic burden worldwide. During chronic stress, the heart undergoes myocardial remodeling, mainly manifested by car

Externí odkaz: https://doaj.org/article/abf8ece8c0cc49bbbd2239bec769e60c

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Bioinformatics-Led Identification of Potential Biomarkers and Inflammatory Infiltrates in Burn Injury

Autor: Zehao Niu, Guoxing Wei, Hao Liang, Xin Wang, Wenjuan Yang, Gang Wei, Jiachang Guo, Yingen Chen, Ran Tao, Jun Niu

Publikováno v: Journal of Burn Care & Research.

Burn injury is a life-threatening disease with a poor prognosis. The immune change and underlying mechanisms remain largely unknown. Thus, this study aims to find potential biomarkers and analyze the immune infiltrates after burn injury. Gene express

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0a179cb48f3b7b8795813e6da031c96f
https://doi.org/10.1093/jbcr/irad050

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Interleukin-5 deletion promotes sepsis-induced M1 macrophage differentiation, deteriorates cardiac dysfunction, and exacerbates cardiac injury via the NF-κB p65 pathway in mice

Autor: Wanqian Liang, Caiyan Bai, Jianhua Li, Guotao Huang, Yan Li, Xuehui Wang, Yingen Chen

Publikováno v: BioFactors (Oxford, England)REFERENCES. 46(6)

Inflammation plays a crucial role in sepsis-induced cardiac injury. The purpose of this study was to determine whether interleukin-5 (IL-5) affected lipopolysaccharide (LPS)-induced cardiac injury by regulating the inflammatory response. First, the e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::470aa7fe2a5252ec13a23a6f61824236
https://pubmed.ncbi.nlm.nih.gov/33043521

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Salidroside downregulates microRNA‑133a and inhibits endothelial cell apoptosis induced by oxidized low‑density lipoprotein

Autor: Guoan Zhao, Zhigang Yan, Yingen Chen, Fei Lin, Zhigang Chen, Yilin Zhao, Yongjie Zhang

Publikováno v: International Journal of Molecular Medicine

Vascular endothelial cell apoptosis is regulated by microRNA-133a (miR-133a), which participates in the formation of atherosclerotic (AS) plaques, leading to the development of several cardiovascular diseases. Salidroside (SAL), the main component of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d183e8575ab4727f8a96e68b22a808ac
https://doi.org/10.3892/ijmm.2020.4691

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