Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Yingchun Shao"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The pursuit of effective treatments for brain tumors has increasingly focused on the promising area of nanoparticle-enhanced radiotherapy (NERT). This review elucidates the context and significance of NERT, with a particular emphasis on its applicati
Externí odkaz:
https://doaj.org/article/b00b602160f34657b32282349b19caae
Autor:
Wujun Chen, Xiaolin Wu, Jianxia Hu, Xiaolei Liu, Zhu Guo, Jianfeng Wu, Yingchun Shao, Minglu Hao, Shuangshuang Zhang, Weichao Hu, Yanhong Wang, Miao Zhang, Meng Zhu, Chao Wang, Yudong Wu, Jie Wang, Dongming Xing
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Atherosclerosis is one of the leading causes of death worldwide. miR-26 is a potential biomarker of atherosclerosis. Standardized diagnostic tests for miR-26 (MIR26-DX) have been developed, but the fastest progress has been in predicting the
Externí odkaz:
https://doaj.org/article/7b161dbc163f4e7a9a4ed16ae9ac1163
Publikováno v:
Zhongguo shuxue zazhi, Vol 36, Iss 11, Pp 995-999 (2023)
Objective To investigate the clinical characteristics and diagnosis and treatment of passenger lymphocyte syndrome (PLS) in patients following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Methods A total of 489 patients who underwe
Externí odkaz:
https://doaj.org/article/e34c42b7d4634946b2c13a2f1f7a1b1f
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-13 (2023)
Abstract Dysregulation of histone modifications has been implicated in the pathogenesis of both inflammatory bowel disease (IBD) and colorectal cancer (CRC). These diseases are characterized by chronic inflammation, and alterations in histone modific
Externí odkaz:
https://doaj.org/article/f3e27f033e804e3daa65e2b918c3c681
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Growth differentiation factor 11 (GDF11) is one of the important factors in the pathophysiological process of animals. It is widely expressed in many tissues and organs of animals, showing its wide biological activity and potential application value.
Externí odkaz:
https://doaj.org/article/2b3f81dd305f43e8b7c76dec48d979df
Autor:
Yingchun Shao, Jiazhen Xu, Bing Liang, Shuangshuang Zhang, Wujun Chen, Yanhong Wang, Dongming Xing
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 167, Iss , Pp 115589- (2023)
Cerebellar degeneration-related protein 1 antisense RNA (CDR1as), also known as ciRS-7, is a circular natural antisense transcript of CDR1. It is a widely studied and powerful representative of circular RNAs. Based on its widely reported role in canc
Externí odkaz:
https://doaj.org/article/4aa4e9ae93c945cca4064816eb7514bc
Autor:
Shanbo Yang, Chao Wang, Lingyu Shi, Jing Chang, Yujing Zhang, Jingsen Meng, Wenjing Liu, Jun Zeng, Renshuai Zhang, Yingchun Shao, Dongming Xing
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 2755-2764 (2022)
A set of novel diarylpyridines as anti-tubulin agents were designed, synthesised using a rigid pyridine as a linker to fix the cis-orientation of ring-A and ring-B. All of the target compounds were evaluated for their in vitro antiproliferative activ
Externí odkaz:
https://doaj.org/article/54bb24125c124900bb988da63e194a86
Autor:
Mengmeng Li, BE, Lei Jiao, PhD, Yingchun Shao, BE, Haodong Li, BS, Lihua Sun, PhD, Qi Yu, MM, Manyu Gong, BE, Dongping Liu, BS, Yanying Wang, M.M, Lina Xuan, PhD, Xuewen Yang, MM, Yunmeng Qu, BS, Yaqi Wang, BS, Lintong Jiang, BS, Jingjing Han, BS, Ying Zhang, PhD, Yong Zhang, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 7, Iss 9, Pp 880-895 (2022)
Summary: The most devastating and catastrophic deterioration of myocardial ischemia-reperfusion injury (MIRI) is cardiomyocyte death. Here we aimed to evaluate the role of lncRNA-ZFAS1 in MIRI and delineate its mechanism of action. The level of lncRN
Externí odkaz:
https://doaj.org/article/b0b0e4f664a44ebca0c156f914002ccc
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Main protease (Mpro) is a superior target for anti-SARS-COV-2 drugs. PF-07304814 is a phosphate ester prodrug of PF-00835231 that is rapidly metabolized into the active metabolite PF-00835231 by alkaline phosphatase (ALP) and then suppresses SARS-CoV
Externí odkaz:
https://doaj.org/article/6e5f53ef1af64e0da8d311f54844b2df
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Cancer is among the leading cause of deaths worldwide. Although conventional therapies have been applied in the fight against the cancer, the poor oxygen, low extracellular pH, and high interstitial fluid pressure of the tumor microenvironment mean t
Externí odkaz:
https://doaj.org/article/eb0c3eee2d974b7c84b9633297da0020