Zobrazeno 1 - 10
of 238
pro vyhledávání: '"YingLan Zhao"'
Autor:
Liang Wang, Ziyun Yang, Fudo Satoshi, Xavier Prasanna, Ziyi Yan, Helena Vihinen, Yaxing Chen, Yue Zhao, Xiumei He, Qian Bu, Hongchun Li, Ying Zhao, Linhong Jiang, Feng Qin, Yanping Dai, Ni Zhang, Meng Qin, Weihong Kuang, Yinglan Zhao, Eija Jokitalo, Ilpo Vattulainen, Tommi Kajander, Hongxia Zhao, Xiaobo Cen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-30 (2024)
Abstract The Bin/Amphiphysin/Rvs (BAR) domain protein FAM92A1 is a multifunctional protein engaged in regulating mitochondrial ultrastructure and ciliogenesis, but its physiological role in the brain remains unclear. Here, we show that FAM92A1 is exp
Externí odkaz:
https://doaj.org/article/345ca2ed37524fef9b09f5e108e25a96
Autor:
Na Su, Rui Tang, Yice Zhang, Jiaqi Ni, Yimei Huang, Chunqi Liu, Yuzhou Xiao, Baoting Zhu, Yinglan Zhao
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectivesThis study aimed to identify the risk factors for pancreatic cancer through machine learning.MethodsWe investigated the relationships between different risk factors and pancreatic cancer using a real-world retrospective cohort study conduct
Externí odkaz:
https://doaj.org/article/777ffb68aa704d1091554f84d5162070
Autor:
Yue Zhou, Lei Tao, Jiahao Qiu, Jing Xu, Xinyu Yang, Yu Zhang, Xinyu Tian, Xinqi Guan, Xiaobo Cen, Yinglan Zhao
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-86 (2024)
Abstract Tumor biomarkers, the substances which are produced by tumors or the body’s responses to tumors during tumorigenesis and progression, have been demonstrated to possess critical and encouraging value in screening and early diagnosis, progno
Externí odkaz:
https://doaj.org/article/b9b87e7c535e44fabd411489fac5d03f
Autor:
Lei Tao, Yue Zhou, Yuan Luo, Jiahao Qiu, Yuzhou Xiao, Jiao Zou, Yu Zhang, Xingchen Liu, Xinyu Yang, Kun Gou, Jing Xu, Xinqi Guan, Xiaobo Cen, Yinglan Zhao
Publikováno v:
MedComm – Oncology, Vol 3, Iss 1, Pp n/a-n/a (2024)
Abstract Epigenetic regulation refers to the alteration of gene expression independent of changes in DNA sequence. It involves chemical modifications such as DNA methylation, histone methylation, and histone acetylation, which are regulated by a coor
Externí odkaz:
https://doaj.org/article/8faf30fe123b49e78b7d9110f48eaa3a
Autor:
Lei Tao, Yue Zhou, Xiangyu Pan, Yuan Luo, Jiahao Qiu, Xia Zhou, Zhiqian Chen, Yan Li, Lian Xu, Yang Zhou, Zeping Zuo, Chunqi Liu, Liang Wang, Xiaocong Liu, Xinyu Tian, Na Su, Zhengnan Yang, Yu Zhang, Kun Gou, Na Sang, Huan Liu, Jiao Zou, Yuzhou Xiao, Xi Zhong, Jing Xu, Xinyu Yang, Kai Xiao, Yanyang Liu, Shengyong Yang, Yong Peng, Junhong Han, Xiaobo Cen, Yinglan Zhao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Poly (ADP-ribose) polymerase inhibitors (PARPi) are selectively active in ovarian cancer (OC) with homologous recombination (HR) deficiency (HRD) caused by mutations in BRCA1/2 and other DNA repair pathway members. We sought molecular target
Externí odkaz:
https://doaj.org/article/e1edd8a2f3964d08b411d2a531262c72
Publikováno v:
Land, Vol 13, Iss 7, p 975 (2024)
As economic development continues to advance globally, countries are increasingly focused on the green transformation of their economies. This paper employs a data envelopment analysis (DEA) model and entropy weighting methodology to construct and as
Externí odkaz:
https://doaj.org/article/3792a0f20413474d82a4e106082d9787
Autor:
Liang Wang, Xiaojie Wang, Chunqi Liu, Wei Xu, Weihong Kuang, Qian Bu, Hongchun Li, Ying Zhao, Linhong Jiang, Yaxing Chen, Feng Qin, Shu Li, Qinfan Wei, Xiaocong Liu, Bin Liu, Yuanyuan Chen, Yanping Dai, Hongbo Wang, Jingwei Tian, Gang Cao, Yinglan Zhao, Xiaobo Cen
Publikováno v:
Genomics, Proteomics & Bioinformatics, Vol 21, Iss 3, Pp 551-572 (2023)
The expression of linear DNA sequence is precisely regulated by the three-dimensional (3D) architecture of chromatin. Morphine-induced aberrant gene networks of neurons have been extensively investigated; however, how morphine impacts the 3D genomic
Externí odkaz:
https://doaj.org/article/900dc1e7521743ac9175b78cba46f217
Autor:
Shaomin Wang, Liang Wang, Qian Bu, Qian Wei, Linhong Jiang, Yanping Dai, Ni Zhang, Weihong Kuang, Yinglan Zhao, Xiaobo Cen
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Methamphetamine (METH) abuse by pregnant drug addicts causes toxic effects on fetal neurodevelopment; however, the mechanism underlying such effect of METH is poorly understood.Methods: In the present study, we applied three-dimensional
Externí odkaz:
https://doaj.org/article/fb4ebe2c46e045f3a59c83d11bc7b81f
Pharmacological inhibition of LSD1 suppresses growth of hepatocellular carcinoma by inducing GADD45B
Autor:
Na Sang, Xi Zhong, Kun Gou, Huan Liu, Jing Xu, Yang Zhou, Xia Zhou, Yuanzhi Liu, Zhiqian Chen, Yue Zhou, Yan Li, Lei Tao, Na Su, Lingyun Zhou, Jiahao Qiu, Xinyu Yang, Zeping Zuo, Li Fu, Jingyao Zhang, Dan Li, Cong Li, Qingxiang Sun, Jian Lei, Rui Li, Shengyong Yang, Xiaobo Cen, Yinglan Zhao
Publikováno v:
MedComm, Vol 4, Iss 3, Pp n/a-n/a (2023)
Abstract Lysine‐specific histone demethylase 1 (LSD1) is an attractive target for malignancies therapy. Nevertheless, its role in hepatocellular carcinoma (HCC) progression and the potential of its inhibitor in HCC therapy remains unclear. Here, we
Externí odkaz:
https://doaj.org/article/ab847cd559a74dc58dab789332dfddab
Autor:
Xiaowei Yang, Chungen Li, Kun Gou, Xiaocong Liu, Yue Zhou, Jiao Zou, Qiang Chen, Youfu Luo, Yinglan Zhao
Publikováno v:
MedComm – Oncology, Vol 1, Iss 1, Pp n/a-n/a (2022)
Abstract Dihydroorotate dehydrogenase (DHODH) is a quite attractive target in cancer therapy. Nevertheless, the antitumor effects of DHODH inhibitors against colorectal cancer (CRC) and the underlying mechanism have seldom been studied. Here, we expl
Externí odkaz:
https://doaj.org/article/ba82b92109ad4d55aa385143769f2678