Zobrazeno 1 - 10
of 409
pro vyhledávání: '"YingHong Li"'
Autor:
Yinghong Li, Ye Xu, Biwei Zhang, Zhigang Wang, Leilei Ma, Longyu Sun, Xiuping Wang, Yimin Lin, Ji-an Li, Chenxi Wu
Publikováno v:
Journal of Traditional and Complementary Medicine, Vol 14, Iss 4, Pp 424-434 (2024)
Background and aim: Type-2 diabetes mellitus (T2DM) is mainly characterized by insulin resistance (IR) induced by hyperglycaemia and insufficient insulin secretion. We employed a diabetic fly model to examine the effect and molecular mechanism of Atr
Externí odkaz:
https://doaj.org/article/5fd4020fdd5c4fe184331d0157a69626
Autor:
Hongrui Duo, Yinghong Li, Yang Lan, Jingxin Tao, Qingxia Yang, Yingxue Xiao, Jing Sun, Lei Li, Xiner Nie, Xiaoxi Zhang, Guizhao Liang, Mingwei Liu, Youjin Hao, Bo Li
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-29 (2024)
Abstract Background Single-cell RNA sequencing (scRNA-seq) and spatially resolved transcriptomics (SRT) have led to groundbreaking advancements in life sciences. To develop bioinformatics tools for scRNA-seq and SRT data and perform unbiased benchmar
Externí odkaz:
https://doaj.org/article/279b7d0c771b4ebb83b4a5bb4b170b10
Autor:
Hongying Li, Jianrui Li, Jiayu Li, Hu Li, Xuekai Wang, Jing Jiang, Lei Lei, Han Sun, Mei Tang, Biao Dong, Weiqing He, Shuyi Si, Bin Hong, Yinghong Li, Danqing Song, Zonggen Peng, Yongsheng Che, Jian-Dong Jiang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 6, Pp 2567-2580 (2024)
The pandemic of SARS-CoV-2 worldwide with successive emerging variants urgently calls for small-molecule oral drugs with broad-spectrum antiviral activity. Here, we show that carrimycin, a new macrolide antibiotic in the clinic and an antiviral candi
Externí odkaz:
https://doaj.org/article/0c69026a221e410791cdc5a1b0b2f32b
Autor:
Peiqing Huang, Rongrong Sun, Chenchang Xu, Zixuan Jiang, Muqiu Zuo, Yinghong Li, Rui Liu, Pixia Gong, Yuyi Han, Jiankai Fang, Peishan Li, Changshun Shao, Yufang Shi
Publikováno v:
Cell Death and Disease, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Glucocorticoid (GC) is essential for maintaining immune homeostasis. While GC is known to regulate the expression of genes related to inflammation in immune cells, the effects of GC, especially in the presence of inflammation, on non-immune
Externí odkaz:
https://doaj.org/article/56cae632e31344069b544576f3997f83
Publikováno v:
Epilepsia Open, Vol 8, Iss 4, Pp 1452-1459 (2023)
Abstract Objective Observational studies have shown an association between COVID‐19 and epilepsy. However, causality remains unproven. This study aimed to investigate the causative effect of genetically predicted COVID‐19 phenotypes on epilepsy r
Externí odkaz:
https://doaj.org/article/992f2680ecbd4a8c848211acf9e90060
Publikováno v:
Materials Research Letters, Vol 11, Iss 12, Pp 973-1012 (2023)
The aviation industry is a key market that promote additive manufacturing (AM) technology since there are huge demands for precision manufacture of high-value complex structural parts and repair of local defects. Extensive research has been conducted
Externí odkaz:
https://doaj.org/article/d73a473dbc474e7f80936f861264cb74
Autor:
Zhiwen Li, Zhihao Guo, Xi Lu, Xican Ma, Xiukun Wang, Rui Zhang, Xinxin Hu, Yanxiang Wang, Jing Pang, Tianyun Fan, Yonghua Liu, Sheng Tang, Haigen Fu, Jingpu Zhang, Yinghong Li, Xuefu You, Danqing Song
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 7, Pp 3067-3079 (2023)
A series of new monobactam sulfonates is continuously synthesized and evaluated for their antimicrobial efficacies against Gram-negative bacteria. Compound 33a (IMBZ18G) is highly effective in vitro and in vivo against clinically intractable multi-dr
Externí odkaz:
https://doaj.org/article/c4018a493f624090a0577c95b7c556ad
Autor:
Wei Wei, Qingxuan Zeng, Yan Wang, Xixi Guo, Tianyun Fan, Yinghong Li, Hongbin Deng, Liping Zhao, Xintong Zhang, Yonghua Liu, Yulong Shi, Jingyang Zhu, Xican Ma, Yanxiang Wang, Jiandong Jiang, Danqing Song
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 3, Pp 1477- (2024)
Externí odkaz:
https://doaj.org/article/5f414f4da0054e8b8ae7723012175d8e
Autor:
Wei Wei, Qingxuan Zeng, Yan Wang, Xixi Guo, Tianyun Fan, Yinghong Li, Hongbin Deng, Liping Zhao, Xintong Zhang, Yonghua Liu, Yulong Shi, Jingyang Zhu, Xican Ma, Yanxiang Wang, Jiandong Jiang, Danqing Song
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 5, Pp 2138-2151 (2023)
Using chemoproteomic techniques, we first identified EIF2AK2, eEF1A1, PRDX3 and VPS4B as direct targets of berberine (BBR) for its synergistically anti-inflammatory effects. Of them, BBR has the strongest affinity with EIF2AK2 via two ionic bonds, an
Externí odkaz:
https://doaj.org/article/0483950d410d47138ad6e7dfdcd6ab85
Autor:
Huiqiang Wang, Fenbei Chen, Shicong Wang, Yuhuan Li, Ting Liu, Yinghong Li, Hongbin Deng, Jingwen Dong, Jing Pang, Danqing Song, Dousheng Zhang, Juan Yu, Yanxiang Wang
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Hand, foot, and mouth disease (HFMD) caused by enterovirus A71 (EV-A71) infection, currently lacks specific preventive and therapeutic interventions. Here, we demonstrated that Pien Tze Huang (PZH) could dose-dependently inhibit EV-A71 replication at
Externí odkaz:
https://doaj.org/article/c8c09e9a8cf54250acb8daeee8c15836