Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Ying-shu Quan"'
Autor:
Sachiko Hirobe, Taki Yamasaki, Sayami Ito, Ying-Shu Quan, Fumio Kamiyama, Masashi Tachibana, Naoki Okada
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 385 (2022)
We are interested in promoting the development of transcutaneous immunization using microneedle technology and attempting to apply an adjuvant with transcutaneous immunization to improve the efficacy and reduce the amount of antigen and number of adm
Externí odkaz:
https://doaj.org/article/976aa4da38cb4633a9b2a0669c5e2124
Autor:
Sayami Ito, Sachiko Hirobe, Takuto Kawakita, Mio Saito, Ying-Shu Quan, Fumio Kamiyama, Ken J. Ishii, Mizuho Nagao, Takao Fujisawa, Masashi Tachibana, Naoki Okada
Publikováno v:
Pharmaceutics, Vol 12, Iss 3, p 267 (2020)
Transcutaneous immunization (TCI) is easy to use, minimally invasive, and has excellent efficacy in vaccines against infections. We focused on toll-like receptor (TLR) ligands as applicable adjuvants for transcutaneous formulations and characterized
Externí odkaz:
https://doaj.org/article/6e7171d817f94744ab601fe699997f77
Autor:
Chihiro Naito, Hidemasa Katsumi, Tomoko Suzuki, Ying-shu Quan, Fumio Kamiyama, Toshiyasu Sakane, Akira Yamamoto
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 215 (2018)
Human parathyroid hormone (1-34) (PTH) has been widely used as the subcutaneous injection formulation for the treatment of osteoporosis. In the present study, we developed an efficient transdermal delivery system of PTH by using dissolving microneedl
Externí odkaz:
https://doaj.org/article/a7e9b467d2064298b7633e28e9b4173c
Autor:
Akihiko Ono, Sayami Ito, Shun Sakagami, Hideo Asada, Mio Saito, Ying-Shu Quan, Fumio Kamiyama, Sachiko Hirobe, Naoki Okada
Publikováno v:
Pharmaceutics, Vol 9, Iss 4, p 59 (2017)
The authors wish to make a change to their published paper [1].[...]
Externí odkaz:
https://doaj.org/article/a09a2ebeb04f47bd91df0261e1bb12dc
Autor:
Akihiko Ono, Sayami Ito, Shun Sakagami, Hideo Asada, Mio Saito, Ying-Shu Quan, Fumio Kamiyama, Sachiko Hirobe, Naoki Okada
Publikováno v:
Pharmaceutics, Vol 9, Iss 3, p 27 (2017)
Microneedle (MN) patches are promising for transcutaneous vaccination because they enable vaccine antigens to physically penetrate the stratum corneum via low-invasive skin puncturing, and to be effectively delivered to antigen-presenting cells in th
Externí odkaz:
https://doaj.org/article/d4578944afb640dba6b18fb42493c65d
Autor:
Hidemasa Katsumi, Yutaro Tanaka, Kaori Hitomi, Shu Liu, Ying-shu Quan, Fumio Kamiyama, Toshiyasu Sakane, Akira Yamamoto
Publikováno v:
Pharmaceutics, Vol 9, Iss 3, p 29 (2017)
To improve the transdermal bioavailability and safety of alendronate (ALN), a nitrogen-containing bisphosphonate, we developed self-dissolving microneedle arrays (MNs), in which ALN is loaded only at the tip portion of micron-scale needles by a dip-c
Externí odkaz:
https://doaj.org/article/c099ec5352f04f9499b9f750eea2316b
Autor:
Tatsuro Amano, Naoto Fujii, Ying-Shu Quan, Glen P. Kenny, Narihiko Kondo, Hirofumi Yamashita, Yoshimitsu Inoue
Publikováno v:
Journal of Controlled Release. 358:161-170
Autor:
Naoki Oiso, Yuta Kimura, Kenji Kabashima, Shota Hatanaka, Ying-Shu Quan, Takashi Nakayama, Yuta Hara, Fumio Kamiyama, Kazuhiko Matsuo, Keiji Nishiwaki, Akira Kawada
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 109, Iss, Pp 1437-1444 (2019)
CCR4 is a chemokine receptor highly expressed by Th2 cells, and regarded as a potential therapeutic target for atopic dermatitis (AD). CCL17 and CCL22 are the CCR4 ligands, and thymic stromal lymphopoietin (TSLP) is shown to promote the expression of
Autor:
Sachiko Hirobe, Mizuho Nagao, Sayami Ito, Mio Saito, Takao Fujisawa, Yu Kuwabara, Fumio Kamiyama, Ying-Shu Quan, Naoki Okada
Publikováno v:
Pharmaceutical Research. 37
Epicutaneous immunotherapy (EPIT) involving the skin’s immune system is easy to use, painless and has a low risk of systemic side effects; it can be applied to food allergies that have a high morbidity rate in children. In this study, we evaluated
Publikováno v:
Oleoscience. 17:567-574