Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Ying-Nai Wang"'
Autor:
Chunxiao Liu, Chenhao Zhou, Weiya Xia, Yifan Zhou, Yufan Qiu, Jialei Weng, Qiang Zhou, Wanyong Chen, Ying-Nai Wang, Heng-Huan Lee, Shao-Chun Wang, Ming Kuang, Dihua Yu, Ning Ren, Mien-Chie Hung
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Tumor-secreted factors contribute to the development of a microenvironment that facilitates the escape of cancer cells from immunotherapy. In this study, we conduct a retrospective comparison of the proteins secreted by hepatocellular carcin
Externí odkaz:
https://doaj.org/article/fec4a1384c9b4097a6c58e39022e975c
Autor:
Yun-Long Wang, Wan-Wen Zhao, Shao-Mei Bai, Yan Ma, Xin-Ke Yin, Li-Li Feng, Guang-Dong Zeng, Fang Wang, Wei-Xing Feng, Jian Zheng, Ying-Nai Wang, Bing Zeng, Quentin Liu, Mien-Chie Hung, Xiang-Bo Wan
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-13 (2022)
Abstract Paraspeckles are mammal-specific membraneless nuclear bodies that participate in various biological processes. NONO, a central paraspeckle component, has been shown to play pivotal roles in DNA double-strand breaks (DSB) repair, whereas its
Externí odkaz:
https://doaj.org/article/67b2f196f89c4d2e98e308070287c485
Autor:
Yun-Long Wang, Wan-Wen Zhao, Shao-Mei Bai, Li-Li Feng, Shu-Ying Bie, Li Gong, Fang Wang, Ming-Biao Wei, Wei-Xing Feng, Xiao-Lin Pang, Cao-Litao Qin, Xin-Ke Yin, Ying-Nai Wang, Weihua Zhou, Daniel R. Wahl, Quentin Liu, Ming Chen, Mien-Chie Hung, Xiang-Bo Wan
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The MRN complex is a critical sensor and processor of DNA double-strand breaks (DSBs). Here, the authors show that MRNIP forms liquid-like condensates to accelerate the MRN-mediated sensing and end resection of DSB, thereby promoting DSB repair.
Externí odkaz:
https://doaj.org/article/0d2d630dc0a747b8807be46604e76da1
Autor:
Heng-Huan Lee, Ying-Nai Wang, Wen-Hao Yang, Weiya Xia, Yongkun Wei, Li-Chuan Chan, Yu-Han Wang, Zhou Jiang, Shouping Xu, Jun Yao, Yufan Qiu, Yi-Hsin Hsu, Wei-Lun Hwang, Meisi Yan, Jong-Ho Cha, Jennifer L. Hsu, Jia Shen, Yuanqing Ye, Xifeng Wu, Ming-Feng Hou, Lin-Ming Tseng, Shao-Chun Wang, Mei-Ren Pan, Chin-Hua Yang, Yuan-Liang Wang, Hirohito Yamaguchi, Da Pang, Gabriel N. Hortobagyi, Dihua Yu, Mien-Chie Hung
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Human ribonuclease 1 (hRNase 1) regulates innate immunity, hemostasis and RNA clearance. Here, the authors report an alternative function of hRNase 1 as a secretory ligand of Eph receptor EphA4 to enhance breast cancer stemness and promote breast tum
Externí odkaz:
https://doaj.org/article/951d591c8f644e74b61e110feda5e096
Autor:
Ying-Nai Wang, Heng-Huan Lee, Yongkun Wei, Yu-Yi Chu, Weiya Xia, Michael Wang, Dihua Yu, Mien-Chie Hung
Publikováno v:
STAR Protocols, Vol 3, Iss 1, Pp 101198- (2022)
Summary: Immunotherapy via PD-1/PD-L1 blockade is a promising strategy to eradicate cancer cells. However, the PD-L1 pathological level is inconsistent with the therapeutic response and is not a reliable biomarker to stratify patients for anti-PD-1/P
Externí odkaz:
https://doaj.org/article/5ee966d3eadc4c6cabc5f6119e5cb1fd
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-11 (2020)
Abstract N-linked glycosylation is one of the most abundant posttranslational modifications of membrane-bound proteins in eukaryotes and affects a number of biological activities, including protein biosynthesis, protein stability, intracellular traff
Externí odkaz:
https://doaj.org/article/c38fc244b9d140be82e3ed6062b17aa8
A novel ligand-receptor relationship between families of ribonucleases and receptor tyrosine kinases
Publikováno v:
Journal of Biomedical Science, Vol 25, Iss 1, Pp 1-15 (2018)
Abstract Pancreatic ribonuclease is known to participate in host defense system against pathogens, such as parasites, bacteria, and virus, which results in innate immune response. Nevertheless, its potential impact to host cells remains unclear. Of i
Externí odkaz:
https://doaj.org/article/44c2021628a94b0d877c457f28b12cf5
Autor:
Ying-Nai Wang, 王盈乃
92
Overexpression of keratin 16 has been observed in keratinocytes in those skin diseases characterized by hyperproliferation such as psoriasis. Therefore, keratin 16 is usually referred to as a disease-associated keratin. In studies of gene reg
Overexpression of keratin 16 has been observed in keratinocytes in those skin diseases characterized by hyperproliferation such as psoriasis. Therefore, keratin 16 is usually referred to as a disease-associated keratin. In studies of gene reg
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/97510927993315419397
Autor:
Yu-Yi Chu, Mei-Kuang Chen, Yongkun Wei, Heng-Huan Lee, Weiya Xia, Ying-Nai Wang, Clinton Yam, Jennifer L. Hsu, Hung-Ling Wang, Wei-Chao Chang, Hirohito Yamaguchi, Zhou Jiang, Chunxiao Liu, Ching-Fei Li, Lei Nie, Li-Chuan Chan, Yuan Gao, Shao-Chun Wang, Jinsong Liu, Shannon N. Westin, Sanghoon Lee, Anil K. Sood, Liuqing Yang, Gabriel N. Hortobagyi, Dihua Yu, Mien-Chie Hung
Publikováno v:
Nature Cancer. 3:1211-1227
Poly(ADP-ribose) polymerase (PARP) inhibitors have demonstrated promising clinical activity in multiple cancers. However, resistance to PARP inhibitors remains a substantial clinical challenge. In the present study, we report that anaplastic lymphoma
Autor:
Mien-Chie Hung, Roy Herbst, How-Wen Ko, Yi Du, Shih-Shin Chang, Ming-Chuan Hsu, Ying-Nai Wang, Chun-Te Chen, Jennifer L. Hsu, Hirohito Yamaguchi
PDF file - 35K, The effects of cisplatin and/or gefitinib on A549-Bcl-XL tumor growth in vivo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bebd14373d6fddeef9d80d4e135eb6a
https://doi.org/10.1158/1078-0432.22449309.v1
https://doi.org/10.1158/1078-0432.22449309.v1