Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Ying-Ju Lai"'
Autor:
Yi-Hsin Chan, Feng-Chun Tsai, Gwo-Jyh Chang, Ying-Ju Lai, Shang-Hung Chang, Wei-Jan Chen, Yung-Hsin Yeh
Publikováno v:
Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-19 (2023)
Abstract Background Sustained, chronic activation of β-adrenergic receptor (β-AR) signaling leads to cardiac arrhythmias, with exchange proteins directly activated by cAMP (Epac1 and Epac2) as key mediators. This study aimed to evaluate whether CD4
Externí odkaz:
https://doaj.org/article/701aa8fd9c4549ef889d3e6014e9bacd
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 15 (2022)
Background Cardiac hypertrophy is associated with abnormal electrophysiology and increased arrhythmia risk. This study assessed whether candesartan cilexetil, an angiotensin II type 1 receptor blocker, could suppress arrhythmogenecity by attenuating
Externí odkaz:
https://doaj.org/article/3513e34a57bb474885b91dcb8b4d423e
Autor:
Ying-Ju Lai, Feng-Chun Tsai, Gwo-Jyh Chang, Shang-Hung Chang, Chung-Chi Huang, Wei-Jan Chen, Yung-Hsin Yeh
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 13 (2022)
Atrial fibrosis is an essential contributor to atrial fibrillation (AF). It remains unclear whether atrial endocardial endothelial cells (AEECs) that undergo endothelial-mesenchymal transition (EndMT) are among the sources of atrial fibroblasts. We s
Externí odkaz:
https://doaj.org/article/b7502b3db98d45b1bfc9a78042c36c5b
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract The prediction accuracy of pulse pressure variation (PPV) for fluid responsiveness was suggested to be unreliable in low tidal volume (VT) ventilation. However, high PEEP can cause ARDS patients relatively hypovolemic and more fluid responsi
Externí odkaz:
https://doaj.org/article/6d290b849cdd41c2b257a2afa57af1eb
Publikováno v:
Journal of the Formosan Medical Association, Vol 119, Iss 1, Pp 300-309 (2020)
Background/purpose: Pulmonary veno-occlusive disease (PVOD) is a rare but fatal cause of pulmonary hypertension reported to be linked to mutations of eukaryotic initiation factor 2 alpha kinase 4 (EIF2AK4), also known as general control nonderepressi
Externí odkaz:
https://doaj.org/article/64bbaeafc8a34a5eb747a19000d04cc2
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 12, Iss 1 (2021)
AbstractGene-set analysis (GSA) is a standard procedure for exploring potential biological functions of a group of genes. The development of its methodology has been an active research topic in recent decades. Many GSA methods, when newly proposed, r
Externí odkaz:
https://doaj.org/article/6da10c1b32df414b828859df370081dc
Autor:
Yi-Hsin Chan, Gwo-Jyh Chang, Ying-Ju Lai, Wei-Jan Chen, Shang-Hung Chang, Li-Man Hung, Chi-Tai Kuo, Yung-Hsin Yeh
Publikováno v:
Cardiovascular Diabetology, Vol 18, Iss 1, Pp 1-14 (2019)
Abstract Background Insulin resistance (IR) is considered as a risk factor for atrial fibrillation (AF) even before diabetes develops. The pathophysiology and underlying mechanism are largely unclear. Methods We investigated the corresponding mechani
Externí odkaz:
https://doaj.org/article/d307551a71664362856544127d40bc2d
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137426 (2015)
Gamma-secretase-mediated Notch3 signaling is involved in smooth muscle cell (SMC) hyper-activity and proliferation leading to pulmonary arterial hypertension (PAH). In addition, Propylthiouracil (PTU), beyond its anti-thyroid action, has suppressive
Externí odkaz:
https://doaj.org/article/13d9e32a524f4450901727be740c33d4
Autor:
Ying-Ju Lai, 賴瀅如
104
The root of Mindfulness originally comes from Buddhist meditation practice. The practice of mindfulness involes focus-attention and open-awareness moment by moment and with acceptance and non-judgemental attitudes toward our daily experience
The root of Mindfulness originally comes from Buddhist meditation practice. The practice of mindfulness involes focus-attention and open-awareness moment by moment and with acceptance and non-judgemental attitudes toward our daily experience
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/mc95t7
Autor:
Ying-Ju Lai, 賴盈如
100
A series of copper(II) complexes [Cu(Ln)B](ClO4)] (n=1 - 3，B= bpy, a；phen, b； dpq, c； dppz, d； dppn, e) have been synthesized and characterized by elemental analysis, X-ray crystal structural, LC/MS, Cyclic Voltammetry and UV-Vis s
A series of copper(II) complexes [Cu(Ln)B](ClO4)] (n=1 - 3，B= bpy, a；phen, b； dpq, c； dppz, d； dppn, e) have been synthesized and characterized by elemental analysis, X-ray crystal structural, LC/MS, Cyclic Voltammetry and UV-Vis s
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/60534443853207790302