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pro vyhledávání: '"Ying-Jen Leu"'
Autor:
Ying-Jen Leu, 呂英震
91
Ribonucleases are widely found in prokaryotes and eukaryotes and play an important role in RNA metabolism. Several ribonucleases in the RNase A superfamily not only possess ribonucleolytic activity but also exhibit other functions. In our lab
Ribonucleases are widely found in prokaryotes and eukaryotes and play an important role in RNA metabolism. Several ribonucleases in the RNase A superfamily not only possess ribonucleolytic activity but also exhibit other functions. In our lab
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/40591917878129040558
Autor:
Sui-Chi Wang, Yun-Ru Pan, Chinpan Chen, Chiu-Feng Wang, Ying-Jen Leu, You-Di Liao, Shu-Ting Chang, Yu‐Ting Hong
Publikováno v:
Nucleic Acids Research. 31:5247-5255
Onconase, a cytotoxic ribonuclease from Rana pipiens, possesses pyroglutamate (Pyr) at the N-terminus and has a substrate preference for uridine-guanine (UG). To identify residues responsible for onconase's cytotoxicity, we cloned the rpr gene from g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4372e666c4d0848c26050498364d1b8d
https://doi.org/10.1093/nar/gkg746
https://doi.org/10.1093/nar/gkg746
Autor:
Yun-Ru Pan, Chinpan Chen, Lih-Woan Chen, Chun-Hua Hsu, Ying-Jen Leu, You-Di Liao, Shih-Hsiung Wu
Publikováno v:
Journal of Molecular Biology. 326:1189-1201
Cytotoxic ribonucleases with antitumor activity are mainly found in the oocytes and early embryos of frogs. Native RC-RNase 4 (RNase 4), consisting of 106 residues linked with four disulfide bridges, is a cytotoxic ribonuclease isolated from oocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694ab58e6ea77b05968c2d768ddd65b1
https://doi.org/10.1016/s0022-2836(02)01472-9
https://doi.org/10.1016/s0022-2836(02)01472-9
Autor:
Sui-Chi Wang, Imameddin Amiraslanov, You-Di Liao, Ying-Jen Leu, Yen-Chywan Liaw, Ya-Yun Hsiao, Shuenn-Shing Chern
Publikováno v:
Journal of Biological Chemistry. 278:7300-7309
The Rana catesbeiana (bullfrog) ribonucleases, which belong to the RNase A superfamily, exert cytotoxicity toward tumor cells. RC-RNase, the most active among frog ribonucleases, has a unique base preference for pyrimidine-guanine rather than pyrimid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff1622264938629d7fb2598af8f9f58b
https://doi.org/10.1074/jbc.m206701200
https://doi.org/10.1074/jbc.m206701200
Publikováno v:
Journal of Biological Chemistry. 273:6395-6401
Rana catesbeiana ribonuclease (RC-RNase) is a pyrimidine-guanine sequence-specific ribonuclease found in R. catesbeiana (bullfrog) oocytes. It possesses both ribonuclease activity and cytotoxicity against tumor cells. We report here for the first tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51381c4501cf3239c9cfbc44eb803328
https://doi.org/10.1074/jbc.273.11.6395
https://doi.org/10.1074/jbc.273.11.6395
Autor:
Ying-Jen Leu, Shuenn-Shing Chern, Sui-Chi Wang, Ya-Yun Hsia, Amiraslanov, Imameddin, Yen-Chywan Liaw, You-Di Liao
Publikováno v:
Journal of Biological Chemistry. 2/28/2003, Vol. 278 Issue 9, p7300. 10p. 2 Color Photographs, 1 Diagram, 4 Charts, 4 Graphs.