Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Ying-Hua Jin"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Inflammation is an innate immune response to infection, and it is the main factor causing bodily injury and other complications in the pathological process. Ginsenoside Rh4 (G-Rh4), a minor ginsenoside of Panax ginseng C. A. Meyer and Panax notoginse
Externí odkaz:
https://doaj.org/article/5e2881b9594e4253ad8309d6d569c245
Publikováno v:
Journal of Ginseng Research, Vol 43, Iss 3, Pp 452-459 (2019)
Background: Ginsenoside compound K(C-K), a major metabolite of ginsenoside, exhibits anticancer activity in various cancer cells and animal models. A cell signaling study has shown that C-K inhibited nuclear factor-kappa B (NF-κB) pathway in human a
Externí odkaz:
https://doaj.org/article/a62a2119bf114fc39da0e8d9b133c793
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Human serum albumin (HSA) is an important component of plasma, which has the functions of maintaining colloid osmotic pressure and capillary membrane stability, promoting blood circulation, and anti-oxidation. Three-dimensional structure of HSA deter
Externí odkaz:
https://doaj.org/article/e50a123421ef4a129823fbf022ea0efd
Publikováno v:
Protein & Cell, Vol 9, Iss 6, Pp 568-579 (2018)
Abstract Annexin A2, a multifunctional tumor associated protein, promotes nuclear factor-kappa B (NF-κB) activation by interacting with NF-κB p50 subunit and facilitating its nuclear translocation. Here we demonstrated that two ginsenosides Rg5 (G-
Externí odkaz:
https://doaj.org/article/7bd8ce91b90940ffaf396f192adf2767
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 13170 (2021)
(20S) ginsenoside Rh2 (G-Rh2), a major bioactive metabolite of ginseng, effectively inhibits the survival and proliferation of human liver cancer cells. However, its molecular targets and working mechanism remain largely unknown. Excitingly, we scree
Externí odkaz:
https://doaj.org/article/e5217d4dc521448d8e187e071e551b58
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9289 (2021)
Signal transducers and activators of transcription 3 (STAT3) acts as a transcriptional signal transducer, converting cytokine stimulation into specific gene expression. In tumor cells, aberrant activation of the tyrosine kinase pathway leads to exces
Externí odkaz:
https://doaj.org/article/911055e80e524cfc970202adadc69cb0
Publikováno v:
Molecules, Vol 26, Iss 13, p 3926 (2021)
Ginsenoside Rk1 and Rg5 are minor ginseng saponins that have received more attention recently because of their high oral bioavailability. Each of them can effectively inhibit the survival and proliferation of human liver cancer cells, but the underly
Externí odkaz:
https://doaj.org/article/a3679306abfe4e99b13fd834840190d6
Publikováno v:
Journal of Ginseng Research, Vol 41, Iss 3, Pp 330-338 (2017)
Background: Ginsenoside Rh2 (G-Rh2) is a ginseng saponin that is widely investigated because of its remarkable antitumor activity. However, the molecular mechanism by which (20S) G-Rh2 triggers its functions and how target animals avoid its cytotoxic
Externí odkaz:
https://doaj.org/article/d9bfb36569234eb9bc424fffe020f2fa
Publikováno v:
Biomolecules, Vol 10, Iss 4, p 528 (2020)
(1) Background: Epithelial-mesenchymal transition (EMT) is an essential step for cancer metastasis; targeting EMT is an important path for cancer treatment and drug development. NF-κB, an important transcription factor, has been shown to be responsi
Externí odkaz:
https://doaj.org/article/d4ad7950643840f981dacd60690d6f94
Autor:
Chun-Ying Liu, Rui-Xin Zhou, Chang-Kai Sun, Ying-Hua Jin, Hong-Shan Yu, Tian-Yang Zhang, Long-Quan Xu, Feng-Xie Jin
Publikováno v:
Journal of Ginseng Research, Vol 39, Iss 3, Pp 221-229 (2015)
Background: Minor ginsenosides, those having low content in ginseng, have higher pharmacological activities. To obtain minor ginsenosides, the biotransformation of American ginseng protopanaxadiol (PPD)-ginsenoside was studied using special ginsenosi
Externí odkaz:
https://doaj.org/article/0bed0accf971477b9bc8f2e8b17ed698