Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Ying-Hsiu Su"'
Autor:
Selena Y. Lin, Wei Xia, Amy K. Kim, Dion Chen, Shelby Schleyer, Lin Choi, Zhili Wang, James P. Hamilton, Harry Luu, Hie-Won Hann, Ting-Tsung Chang, Chi-Tan Hu, Abashai Woodard, Terence P. Gade, Ying-Hsiu Su
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract An optimized hepatocellular carcinoma (HCC)-targeted methylation next generation sequencing assay was developed to discover HCC-associated methylation markers directly from urine for HCC screening. Urine cell-free DNA (ucfDNA) isolated from
Externí odkaz:
https://doaj.org/article/97ab82d66331480894a625b29cff3494
Autor:
Selena Y. Lin, Yih‐Ping Su, Evan R. Trauger, Benjamin P. Song, Emilie G.C. Thompson, Malcolm C. Hoffman, Ting‐Tsung Chang, Yih‐Jyh Lin, Yu‐Lan Kao, Yixiao Cui, Hie‐Won Hann, Grace Park, Fwu‐Shan Shieh, Wei Song, Ying‐Hsiu Su
Publikováno v:
Hepatology Communications, Vol 5, Iss 10, Pp 1649-1659 (2021)
Integrated hepatitis B virus (HBV) DNA, found in more than 85% of HBV‐associated hepatocellular carcinomas (HBV‐HCCs), can play a significant role in HBV‐related liver disease progression. HBV‐host junction sequences (HBV‐JSs), created thro
Externí odkaz:
https://doaj.org/article/ecd60a7c58844130a5ab17d24d328f52
Autor:
Selena Y. Lin, Dina Halegoua-DeMarzio, Peter Block, Yu-Lan Kao, Jesse Civan, Fwu-Shan Shieh, Wei Song, Hie-Won Hann, Ying-Hsiu Su
Publikováno v:
Diagnostics, Vol 13, Iss 9, p 1537 (2023)
Hepatitis B virus (HBV)-host junction sequences (HBV-JSs) has been detected in the urine of patients with HBV infection. This study evaluated HBV-JSs as a marker of minimum residual disease (MRD) and tumor recurrence after treatment in HBV-hepatocell
Externí odkaz:
https://doaj.org/article/4924b7012bf34cc3aebb5a61c75f0761
Publikováno v:
Diagnostics, Vol 13, Iss 4, p 676 (2023)
Hepatocellular carcinoma (HCC) is among the world’s third most lethal cancers. In resource-limited settings (RLS), up to 70% of HCCs are diagnosed with limited curative treatments at an advanced symptomatic stage. Even when HCC is detected early an
Externí odkaz:
https://doaj.org/article/6329f899ebdb4bf5805df043fdd8e018
Autor:
Surbhi Jain, Ying-Hsiu Su, Yih-Ping Su, Sierra McCloud, Ruixia Xue, Tai-Jung Lee, Shu-Chuan Lin, Selena Y. Lin, Wei Song, Jamin D. Steffen, Chi-Tan Hu
Publikováno v:
BMC Gastroenterology, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background Detection of human hepatitis B virus (HBV) DNA in the urine of patients with chronic hepatitis B infection (CHB) has been reported previously, suggesting urine could provide a potential route of horizontal HBV transmission. Howeve
Externí odkaz:
https://doaj.org/article/5f084cb09fb545d8bb5c0fd2e9e6066d
Autor:
Selena Y. Lin, Ting-Tsung Chang, Jamin D. Steffen, Sitong Chen, Surbhi Jain, Wei Song, Yih-Jyh Lin, Ying-Hsiu Su
Publikováno v:
Diagnostics, Vol 11, Iss 8, p 1475 (2021)
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide. The beta-catenin gene, CTNNB1, is among the most frequently mutated in HCC tissues. However, mutational analysis of HCC tumors is hampered by the difficulty of obta
Externí odkaz:
https://doaj.org/article/d4ebd6bb8f1a4c26be9bb3046f9d1053
Autor:
Selena Y. Lin, Adam Zhang, Jessica Lian, Jeremy Wang, Ting-Tsung Chang, Yih-Jyh Lin, Wei Song, Ying-Hsiu Su
Publikováno v:
Cells, Vol 10, Iss 6, p 1294 (2021)
Chronic hepatitis B virus (HBV) infection is the major etiology of hepatocellular carcinoma (HCC), frequently with HBV integrating into the host genome. HBV integration, found in 85% of HBV-associated HCC (HBV–HCC) tissue samples, has been suggeste
Externí odkaz:
https://doaj.org/article/c0b9ee082b0040e084b7a77b3617c0f1
Autor:
Selena Y. Lin, Yue Luo, Matthew M. Marshall, Barbara J. Johnson, Sung R. Park, Zhili Wang, Ying-Hsiu Su
Publikováno v:
Diagnostics, Vol 11, Iss 4, p 650 (2021)
This study assessed three commercially available cell-free DNA (cfDNA) extraction kits and the impact of a PEG-based DNA cleanup procedure (DNApure) on cfDNA quality and yield. Six normal donor urine and plasma samples and specimens from four pregnan
Externí odkaz:
https://doaj.org/article/fbb156e2ce2249ee8af9cf8d53b28b2d
Autor:
Fwu-Shan Shieh, Patrick Jongeneel, Jamin D Steffen, Selena Lin, Surbhi Jain, Wei Song, Ying-Hsiu Su
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182843 (2017)
Identification of viral integration sites has been important in understanding the pathogenesis and progression of diseases associated with particular viral infections. The advent of next-generation sequencing (NGS) has enabled researchers to understa
Externí odkaz:
https://doaj.org/article/1f1b147116314196a8ae92931816bfc5
Autor:
Surbhi Jain, Sitong Chen, Kung-Chao Chang, Yih-Jyh Lin, Chi-Tan Hu, Batbold Boldbaatar, James P Hamilton, Selena Y Lin, Ting-Tsung Chang, Shun-Hua Chen, Wei Song, Stephen J Meltzer, Timothy M Block, Ying-Hsiu Su
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35789 (2012)
Hypermethylation of the glutathione S-transferase π 1 (GSTP1) gene promoter region has been reported to be a potential biomarker to distinguish hepatocellular carcinoma (HCC) from other liver diseases. However, reports regarding how specific a marke
Externí odkaz:
https://doaj.org/article/8157d69ee3964b4d8dbef3aed7b088c5