Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ying-Chang Hsueh"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Current methods to generate cardiomyocytes from induced pluripotent stem cells (iPSc) utilize broad-spectrum pharmacological inhibitors. These methods give rise to cardiomyocytes which are typically immature. Since we have recently demonstra
Externí odkaz:
https://doaj.org/article/fed1b86478eb4f6da5f460e534ce8dfe
Publikováno v:
Physiological Reports, Vol 9, Iss 3, Pp n/a-n/a (2021)
Abstract In this review, we summarize the role of Wnt proteins in cardiomyogenesis. More specifically, we focus on how the development of cardiomyocytes from precursor cells involves a complex interplay between Wnt canonical β‐catenin signaling pa
Externí odkaz:
https://doaj.org/article/d900c84b38f74c2686dc42b6abaa7e22
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 4, Pp 496-503 (2014)
Abstract Although self‐renewal ability of adult mammalian heart has been reported, few pharmacological treatments are known to promote cardiomyocyte regeneration after injury. In this study, we demonstrate that the critical period of stem/progenito
Externí odkaz:
https://doaj.org/article/e8538de01a934122bdffda55dbbffa17
Autor:
Sunny Sun-Kin Chan, Hui-Jing Li, Ying-Chang Hsueh, Desy S Lee, Jyh-Hong Chen, Shiaw-Min Hwang, Chen-Yun Chen, Emily Shih, Patrick C H Hsieh
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14414 (2010)
BACKGROUND: The fibroblast growth factor (FGF) family is essential to normal heart development. Yet, its contribution to cardiomyocyte differentiation from stem cells has not been systemically studied. In this study, we examined the mechanisms and ch
Externí odkaz:
https://doaj.org/article/703a457db3394fbfbe46407deeb5b360
Publikováno v:
Circulation. 142
Induced pluripotent stem (iPS) cells provide a novel avenue to investigate how precursors differentiate into cardiomyocytes. In this study we examined our hypothesis that iPS differentiation is regulated by a balance between cardiogenic and inhibitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::583f2e262c2b50d4613684691bad1530
https://doi.org/10.1161/circ.142.suppl_3.15547
https://doi.org/10.1161/circ.142.suppl_3.15547
Publikováno v:
Physiological Reports
Physiological Reports, Vol 9, Iss 3, Pp n/a-n/a (2021)
Physiological Reports, Vol 9, Iss 3, Pp n/a-n/a (2021)
In this review, we summarize the role of Wnt proteins in cardiomyogenesis. More specifically, we focus on how the development of cardiomyocytes from precursor cells involves a complex interplay between Wnt canonical β‐catenin signaling pathways an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7011659c007e0ec05ca56f3ea24aeda
https://pubmed.ncbi.nlm.nih.gov/33587322
https://pubmed.ncbi.nlm.nih.gov/33587322
Autor:
Jasmine M.F. Wu, Patrick C.H. Hsieh, Li Wha Wu, Hiromitsu Nakauchi, Hui Ju Ch'ang, Ying Chang Hsueh, Chwan Yau Luo
Publikováno v:
Circulation Research. 116:633-641
Rationale: The contribution of bone marrow–borne hematopoietic cells to the ischemic myocardium has been documented. However, a pivotal study reported no evidence of myocardial regeneration from hematopoietic-derived cells. The study did not take i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed1e8c7de02d1182eb285939536c4640
https://doi.org/10.1161/circresaha.116.304564
https://doi.org/10.1161/circresaha.116.304564
Autor:
Patrick C.H. Hsieh, Ying Chang Hsueh, Tien Jui Tsang, Shoei-Shen Wang, You-Tzung Chen, David J. Lundy, Bill Cheng, Erika I. Wei
Publikováno v:
Theranostics
Rationale: Reducing cardiomyocyte death and enhancing their proliferation after myocardial infarction is perhaps the single largest challenge for cardiac tissue regeneration. Survivin (SVV) is the smallest member of the inhibitor of apoptosis (IAP) f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61b318feee802e7d7234c214e210e75
https://pubmed.ncbi.nlm.nih.gov/29158846
https://pubmed.ncbi.nlm.nih.gov/29158846
Autor:
Da Ching Tsai, Chwan Yau Luo, Yi-Dong Lin, Patrick C.H. Hsieh, Erika I. H. Wei, Ying Chang Hsueh, Matthew L. Springer, Ming Long Yeh, Ming Jer Tang, Yu Ning Hu, Jieh Neng Wang, Min Yao Chang
Publikováno v:
Science translational medicine, vol 4, iss 146
Lin, YD; Luo, CY; Hu, YN; Yeh, ML; Hsueh, YC; Chang, MY; et al.(2012). Instructive nanofiber scaffolds with VEGF create a microenvironment for arteriogenesis and cardiac repair. Science Translational Medicine, 4(146). doi: 10.1126/scitranslmed.3003841. UCSF: Retrieved from: http://www.escholarship.org/uc/item/094719gd
Lin, YD; Luo, CY; Hu, YN; Yeh, ML; Hsueh, YC; Chang, MY; et al.(2012). Instructive nanofiber scaffolds with VEGF create a microenvironment for arteriogenesis and cardiac repair. Science Translational Medicine, 4(146). doi: 10.1126/scitranslmed.3003841. UCSF: Retrieved from: http://www.escholarship.org/uc/item/094719gd
Angiogenic therapy is a promising approach for tissue repair and regeneration. However, recent clinical trials with protein delivery or gene therapy to promote angiogenesis have failed to provide therapeutic effects. A key factor for achieving effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4f194e62d4206c6212640d3cba1a741
https://escholarship.org/uc/item/094719gd
https://escholarship.org/uc/item/094719gd
Autor:
Chen Yun Chen, Emily Shih, Shiaw-Min Hwang, Sunny Sun Kin Chan, Patrick C.H. Hsieh, Ying Chang Hsueh, Hui Jing Li, Desy S. Lee, Jyh Hong Chen
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14414 (2010)
PLoS ONE
PLoS ONE
Background The fibroblast growth factor (FGF) family is essential to normal heart development. Yet, its contribution to cardiomyocyte differentiation from stem cells has not been systemically studied. In this study, we examined the mechanisms and cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aae5a7271611d3024643195a531bd61f
https://doi.org/10.1371/journal.pone.0014414
https://doi.org/10.1371/journal.pone.0014414