Prometastatic GPCR CD97 Is a Direct Target of Tumor Suppressor microRNA-126

Autor: Ying Y. Lu, David A. Tirrell, Michael J. Sweredoski, David Huss, Sonja Hess, Rusty Lansford

Publikováno v: ACS Chemical Biology. 9:334-338

Tumor suppressor microRNA-126 (miR-126) is often down-regulated in cancer cells, and its over-expression is found to inhibit cancer metastasis. To elucidate the mechanism of tumor suppression by miR-126, we analyzed the proteomic response to miR-126

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f6c0516a454c5d6992f964bc300e7f5
https://doi.org/10.1021/cb400704n

Drug-Loaded, Bivalent-Bottle-Brush Polymers by Graft-through ROMP

Autor: Ying Y. Lu, Alan O. Burts, David A. Tirrell, Robert H. Grubbs, Jeremiah A. Johnson, Alec C. Durrell, Yan Xia

Publikováno v: Macromolecules. 43:10326-10335

Graft-through ring-opening metathesis polymerization (ROMP) using ruthenium N-heterocyclic carbene catalysts has enabled the synthesis of bottle-brush polymers with unprecedented ease and control. Here we report the first bivalent-brush polymers; the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826686b44689113cb6b70b0535319130
https://doi.org/10.1021/ma1021506

Synthesis and Cell Adhesive Properties of Linear and Cyclic RGD Functionalized Polynorbornene Thin Films

Autor: Ying Y. Lu, Eileen Fong, Wilson C. Ho, Paresma R. Patel, David A. Tirrell, Robert H. Grubbs, Rosemary Conrad Kiser

Described herein is the efficient synthesis and evaluation of bioactive arginine-glycine-aspartic acid (RGD) functionalized polynorbornene-based materials for cell adhesion and spreading. Polynorbornenes containing either linear or cyclic RGD peptide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1002e8d21c03ca45db2e2722fd98b370
https://resolver.caltech.edu/CaltechAUTHORS:20120926-114920502

Residue-specific incorporation of non�canonical amino acids into proteins: recent developments and applications

Autor: Ying Y. Lu, James A. Van Deventer, Jeremiah A. Johnson, David A. Tirrell

Residue-specific incorporation of non-canonical amino acids into proteins allows facile alteration and enhancement of protein properties. In this review, we describe recent technical developments and applications of residue-specific incorporation to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f98aed11520b667daa90c014030dfc21
https://europepmc.org/articles/PMC3008400/

Single-cell transcriptomics reveals tumor microenvironment changes and prognostic gene signatures in hepatocellular carcinoma.

Autor: Wu Y; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huai'an, China., Zhai Y; Shanghai Key Laboratory of Biliary Tract Disease Research, Shanghai Research Center of Biliary Tract Disease, Department of General Surgery, Xinhua Hospital, Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China., Ding Z; Department of Hepatobiliary Surgery, The Affiliated Huaian Hospital of Xuzhou Medical University and Huai'an Second People's Hospital, Huai'an, Jiangsu, China., Xie T; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huai'an, China., Zhu W; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huai'an, China., Zhang C; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huai'an, China., Lu Y; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huai'an, China., Chen Y; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huai'an, China., Ren S; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huai'an, China., Hu Y; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huai'an, China., Li X; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huai'an, China., Zhong F; Department of Laboratory Medicine, The Affiliated Huaian Hospital of Xuzhou Medical University and Huai'an Second People's Hospital, Huai'an, Jiangsu, China. Electronic address: zf15252359695@163.com., Liang Y; Department of Laboratory Medicine, The Affiliated Huaian Hospital of Xuzhou Medical University and Huai'an Second People's Hospital, Huai'an, Jiangsu, China. Electronic address: zhongfei_email@163.com., Wang S; School of Life Science and Food Engineering, Huaiyin Institute of Technology, Huai'an, China. Electronic address: wangshiyan1@gmail.com.

Publikováno v: International immunopharmacology [Int Immunopharmacol] 2024 Dec 25; Vol. 143 (Pt 2), pp. 113317. Date of Electronic Publication: 2024 Oct 23.