Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ying Xue Xie"'
Autor:
Kathryn E. Carnazza, Lauren E. Komer, Ying Xue Xie, André Pineda, Juan Antonio Briano, Virginia Gao, Yoonmi Na, Trudy Ramlall, Vladimir L. Buchman, David Eliezer, Manu Sharma, Jacqueline Burré
Publikováno v:
Cell Reports, Vol 43, Iss 5, Pp 114280- (2024)
Externí odkaz:
https://doaj.org/article/92f1178b930f40d6a128c73a29fb7909
Autor:
Ying Xue Xie, Nima N. Naseri, Jasmine Fels, Parinati Kharel, Yoonmi Na, Diane Lane, Jacqueline Burré, Manu Sharma
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Release of α-synuclein aggregates by neurons instigates spread of pathology in synucleinopathies, but the mechanism remains unclear. Here the authors show that neuronally generated α-synuclein aggregates accumulate within neuronal lysosomes and are
Externí odkaz:
https://doaj.org/article/bb879c277162488aa71514ea44aa89e5
Autor:
Emily M. Grasso, Mayu S. Terakawa, Alex L. Lai, Ying Xue Xie, Trudy F. Ramlall, Jack H. Freed, David Eliezer
Publikováno v:
Journal of Molecular Biology. 435:167710
Complexins play a critical role in regulating SNARE-mediated exocytosis of synaptic vesicles. Evolutionary divergences in complexin function have complicated our understanding of the role these proteins play in inhibiting the spontaneous fusion of ve
Autor:
Kathryn E. Carnazza, Lauren E. Komer, Ying Xue Xie, André Pineda, Juan Antonio Briano, Virginia Gao, Yoonmi Na, Trudy Ramlall, Vladimir L. Buchman, David Eliezer, Manu Sharma, Jacqueline Burré
Publikováno v:
Cell reports. 39(2)
α-synuclein, β-synuclein, and γ-synuclein are abundantly expressed proteins in the vertebrate nervous system. α-synuclein functions in neurotransmitter release by binding to and clustering synaptic vesicles and chaperoning SNARE-complex assembly.