Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ying Xiu TOH"'
Autor:
Zenjiro Sampei, Christine Xing’er Koo, Frannie Jiuyi Teo, Ying Xiu Toh, Taku Fukuzawa, Siok Wan Gan, Takeru Nambu, Adrian Ho, Kiyofumi Honda, Tomoyuki Igawa, Fariyal Ahmed, Cheng-I Wang, Katja Fink, Junichi Nezu
Publikováno v:
Antibodies, Vol 12, Iss 2, p 36 (2023)
To combat infectious diseases, vaccines are considered the best prophylactic strategy for a wide range of the population, but even when vaccines are effective, the administration of therapeutic antibodies against viruses could provide further treatme
Externí odkaz:
https://doaj.org/article/a2953071e1654c75af8815c87546bdba
Autor:
Angeline Rouers, Melissa Hui Yen Chng, Bernett Lee, Menaka P. Rajapakse, Kaval Kaur, Ying Xiu Toh, Durgalakshmi Sathiakumar, Thomas Loy, Tun-Linn Thein, Vanessa W.X. Lim, Amit Singhal, Tsin Wen Yeo, Yee-Sin Leo, Kalpit A. Vora, Danilo Casimiro, Bing Lim, Lisa Tucker-Kellogg, Laura Rivino, Evan W. Newell, Katja Fink
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 5, Pp 100278- (2021)
Summary: Prior immunological exposure to dengue virus can be both protective and disease-enhancing during subsequent infections with different dengue virus serotypes. We provide here a systematic, longitudinal analysis of B cell, T cell, and antibody
Externí odkaz:
https://doaj.org/article/f584c5014186468ab29c7e9b13295ce9
A potent neutralizing antibody with therapeutic potential against all four serotypes of dengue virus
Autor:
Meihui Xu, Roland Zuest, Sumathy Velumani, Farhana Tukijan, Ying Xiu Toh, Ramapraba Appanna, Ern Yu Tan, Daniela Cerny, Paul MacAry, Cheng-I Wang, Katja Fink
Publikováno v:
npj Vaccines, Vol 2, Iss 1, Pp 1-10 (2017)
Dengue: A single vaccine candidate for all strains An antibody-vaccine candidate has been discovered that neutralizes and confers protection against all four strains of dengue virus. Katja Fink, of the Singapore Immunology Network and Nanyang Technol
Externí odkaz:
https://doaj.org/article/d00823a1151b41528cddd99e691c0ef6
Autor:
Kok Loon Wong, Weiqiang Chen, Thavamalar Balakrishnan, Ying Xiu Toh, Katja Fink, Siew-Cheng Wong
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36435 (2012)
Human blood monocytes play a central role in dengue infections and form the majority of virus infected cells in the blood. Human blood monocytes are heterogeneous and divided into CD16(-) and CD16(+) subsets. Monocyte subsets play distinct roles duri
Externí odkaz:
https://doaj.org/article/31e4e7b5ab7c4d97ae9534e685f18d59
Autor:
Thavamalar Balakrishnan, Dennis B Bela-Ong, Ying Xiu Toh, Marie Flamand, Shamala Devi, Mickey B Koh, Martin L Hibberd, Eng Eong Ooi, Jenny G Low, Yee Sin Leo, Feng Gu, Katja Fink
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29430 (2011)
BACKGROUND: Dengue virus is transmitted by mosquitoes and has four serotypes. Cross-protection to other serotypes lasting for a few months is observed following infection with one serotype. There is evidence that low-affinity T and/or B cells from pr
Externí odkaz:
https://doaj.org/article/aa06cb0434b04f069c79e499ec9bdeca
Autor:
Kim S. ROBINSON, Gee Ann TOH, Muhammad Jasrie FIRDAUS, Khek Chian THAM, Pritisha ROZARIO, Chrissie LIM, Ying Xiu TOH, Zhi Heng LAU, Sophie Charlotte BINDER, Jacob MAYER, Carine BONNARD, Florian I. SCHMIDT, John E. A. COMMON, Franklin L. ZHONG
NLRP1 is an innate immune sensor protein that activates inflammasome-driven pyroptotic cell death. Recent work demonstrates that human NLRP1 has evolved to sense viral infections. Whether and how human NLRP1 responds to other infectious agents is unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad76428c5948ff4f0a10289c3b7465b3
https://doi.org/10.1101/2023.01.16.524188
https://doi.org/10.1101/2023.01.16.524188
Autor:
Danilo R. Casimiro, Tsin W. Yeo, Menaka Priyadharsani Rajapakse, Vanessa W. Lim, Bernett Lee, Laura Rivino, Amit Singhal, Bing Lim, Tun-Linn Thein, Thomas Loy, Melissa Hui Yen Chng, Durgalakshmi Sathiakumar, Kalpit A. Vora, Katja Fink, Lisa Tucker-Kellogg, Ying Xiu Toh, Angeline Rouers, Kaval Kaur, Yee Sin Leo, Evan W. Newell
Publikováno v:
Cell Reports Medicine
Cell Reports Medicine, Vol 2, Iss 5, Pp 100278-(2021)
Cell Reports Medicine, Vol 2, Iss 5, Pp 100278-(2021)
Summary Prior immunological exposure to dengue virus can be both protective and disease-enhancing during subsequent infections with different dengue virus serotypes. We provide here a systematic, longitudinal analysis of B cell, T cell, and antibody
Autor:
Danilo R. Casimiro, Lisa Tucker-Kellogg, Ying Xiu Toh, Kaval Kaur, Yee Sin Leo, Durgalakshmi Sathiakumar, Melissa Hui Yen Chng, Laura Rivino, Menaka Priyadharsani Rajapakse, Bing Lim, Bernett Lee, Kalpit A. Vora, Katja Fink, Angeline Rouers, Evan W. Newell
Publikováno v:
SSRN Electronic Journal.
Prior immunological exposure to dengue virus can be both protective and disease-enhancing during subsequent infections with different dengue virus serotypes. We provide here for the first time a systematic, longitudinal analysis of B cell, T cell, an
Autor:
Cheng-I Wang, Kandhadayar G. Srinivasan, Michael Poidinger, Daniel Carbajo, Francesca Zolezzi, Mei Hui Xu, Sumathy Velumani, Ying-Xiu Toh, Chia Yin Lee, Tun-Linn Thein, Yee Sin Leo, Ramapraba Appanna, Roland Zuest, Katja Fink, Weili Xu, Bernett Lee, Thavamalar Balakrishnan
Publikováno v:
EBioMedicine, Vol 12, Iss C, Pp 178-188 (2016)
EBioMedicine
EBioMedicine
Dengue is endemic in tropical countries worldwide and the four dengue virus serotypes often co-circulate. Infection with one serotype results in high titers of cross-reactive antibodies produced by plasmablasts, protecting temporarily against all ser
Autor:
Josephine Lum, Hui Yee Yong, Victor Ho, Katja Fink, Marion Chevrier, Vipin Narang, Bernett Lee, Ern Yu Tan, Dahai Luo, Ying-Xiu Toh, Jinmiao Chen
Publikováno v:
Journal of Virology
Short hairpin RNA ligands that activate RIG-I induce antiviral responses in infected cells and prevent or control viral infections. Here, we characterized a new short hairpin RNA molecule with high efficacy in antiviral gene activation and showed tha