Výsledky vyhledávání - "Ying Xiong, PhD"

Akademický článek

Vascular smooth muscle cell mechanotransduction through serum and glucocorticoid inducible kinase-1 promotes interleukin-6 production and macrophage accumulation in murine hypertension

Autor: Mario Figueroa, MD, SarahRose Hall, BS, Victoria Mattia, BS, Alex Mendoza, BS, Adam Brown, BS, Ying Xiong, PhD, Rupak Mukherjee, PhD, Jeffrey A. Jones, PhD, William Richardson, PhD, Jean Marie Ruddy, MD

Publikováno v: JVS - Vascular Science, Vol 4, Iss , Pp 100124- (2023)

Objective: The objective of this investigation was to demonstrate that in vivo induction of hypertension (HTN) and in vitro cyclic stretch of aortic vascular smooth muscle cells (VSMCs) can cause serum and glucocorticoid-inducible kinase (SGK-1)-depe

Externí odkaz: https://doaj.org/article/2fe44dd45d2e4d63aced5615d4a280fb

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Akademický článek

Mechanical activation of the angiotensin II type 1 receptor contributes to abdominal aortic aneurysm formation

Autor: SarahRose Hall, BA, Nicholas D. Ward, MD, Raj Patel, BS, Armaan Amin-Javaheri, BS, Hayes Lanford, BS, R. Tyler Grespin, MS, Christine Couch, MS, Ying Xiong, PhD, Rupak Mukherjee, PhD, Jeffrey A. Jones, PhD, Jean Marie Ruddy, MD

Publikováno v: JVS - Vascular Science, Vol 2, Iss , Pp 194-206 (2021)

Objective: The angiotensin II type 1 receptor (AT1R) can be activated under conditions of mechanical stretch in some cellular systems. Whether this activity influences signaling within the abdominal aorta to promote to abdominal aortic aneurysm (AAA)

Externí odkaz: https://doaj.org/article/24799a201e62495fb17795151f0f7fe2

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