Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ying N. Chan"'
Autor:
Austin W. Boesch, Nana Y Osei-Owusu, Andrew R Crowley, Thach H Chu, Ying N Chan, Joshua A Weiner, Pranay Bharadwaj, Rufus Hards, Mark E Adamo, Scott A Gerber, Sarah L Cocklin, Joern E Schmitz, Adam R Miles, Joshua W Eckman, Aaron J Belli, Keith A Reimann, Margaret E Ackerman
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Antibodies raised in Indian rhesus macaques (Macaca mulatta, MM) in many preclinical vaccine studies are often evaluated in vitro for titer, antigen-recognition breadth, neutralization potency, and/or effector function, and in vivo for potential asso
Externí odkaz:
https://doaj.org/article/a4893b67a6d24fc88a58bfb68b44eee2
Autor:
Mangala Rao, Ying N. Chan, Galit Alter, Nana Yaw Osei-Owusu, Genoveffa Franchini, Alison E. Mahan, Erica Normandin, Jennifer I. Lai, Margaret E. Ackerman, Eric P. Brown, Monica Vaccari
Publikováno v:
Journal of Immunological Methods. 425:27-36
Glycosylation of the Fc domain is an important driver of antibody effector function. While assessment of antibody glycoform compositions observed across total plasma IgG has identified differences associated with a variety of clinical conditions, in
Publikováno v:
mAbs
Non-human primate (NHP) studies are often an essential component of antibody development efforts before human trials. Because the efficacy or toxicity of candidate antibodies may depend on their interactions with Fcγ receptors (FcγR) and their resu
Autor:
Rebecca A. Howell, Nana Yaw Osei-Owusu, Andrew R. Crowley, Ying N. Chan, Margaret E. Ackerman, Joshua W. Eckman, Caitlyn H. Linde, Isaac Zentner, Ali Emileh, Joern E. Schmitz, Samantha L. Finstad, Sarah L. Cocklin, Simon Cocklin, Austin W. Boesch, Adam R. Miles, Galit Alter
Indian rhesus macaques (Macaca mulatta) are routinely used in preclinical studies to evaluate therapeutic Abs and candidate vaccines. The efficacy of these interventions in many cases is known to rely heavily on the ability of Abs to interact with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9a3dc0783f3de9d68f49fb2534a8c9c
https://europepmc.org/articles/PMC5026948/
https://europepmc.org/articles/PMC5026948/