Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Ying Jun Cao"'
Autor:
Tong Zhu, Kathy Cho, Mark Matson, Taiji Sawamoto, Michaelene Lewand, Udaya Valluri, James Keirns, Kenneth C. Lasseter, Suzanne K. Swan, John Holman, Ying Jun Cao
Publikováno v:
Clinical Pharmacology in Drug Development. 5:435-449
Two randomized, double-blind, placebo-controlled studies are reported that had the objective to evaluate the pharmacokinetics, pharmacodynamics, and safety of ASP015K (peficitinib), a Janus kinase (JAK) inhibitor, in healthy subjects. The single-dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba5a3e2da2227a1d4e3f644147a68b32
https://doi.org/10.1002/cpdd.273
https://doi.org/10.1002/cpdd.273
Autor:
Ying Jun Cao, Rahul P. Bakshi, Edward J. Fuchs, Craig W. Hendrix, Jean Anderson, Stephanie Everts, Steven R. Tannenbaum, Nicolette A. Louissaint, Rosa G. Liberman, Paul L. Skipper, Sridhar Nimmagadda
Publikováno v:
AIDS Research and Human Retroviruses. 29:1443-1450
HIV seroconversion outcomes in preexposure prophylaxis (PrEP) trials of oral tenofovir (TFV)-containing regimens are highly sensitive to drug concentration, yet less-than-daily dosing regimens are under study. Description of TFV and its active moiety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb81297eeca61940f65e446b39df18b
https://doi.org/10.1089/aid.2013.0044
https://doi.org/10.1089/aid.2013.0044
Publikováno v:
Applied Mechanics and Materials. :668-671
In order to analyze the ogive effects PELE broken Finite-Thickness reinforced concrete (RC) targets, a variety of shape and materials ogive for PELE penetration 24 millimeters RC targets was analyzed using numerical simulation by LS-DYNA 3D finite el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7c568a761c3d9c553462fdf4f6161dc
https://doi.org/10.4028/www.scientific.net/amm.184-185.668
https://doi.org/10.4028/www.scientific.net/amm.184-185.668
Publikováno v:
Clinical Pharmacology & Therapeutics. 90:151-156
Many antiretroviral (ARV) drugs have large blood plasma-to-seminal plasma (BP/SP) concentration ratios. Concern exists that these drugs do not adequately penetrate the male genital tract (MGT), resulting in the MGT becoming a “pharmacological sanct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c739b5d39a095166852066e86a9928d
https://doi.org/10.1038/clpt.2011.99
https://doi.org/10.1038/clpt.2011.99
Autor:
Alexander G. Agthe, Craig W. Hendrix, Estelle B. Gauda, Ying Jun Cao, Howard Lee, Hong Guang Xie
Publikováno v:
The Journal of Clinical Pharmacology. 51:502-511
The population pharmacokinetic (PK) profile of oral clonidine was characterized in newborns with neonatal abstinence syndrome, and significant covariates affecting its PK parameters were identified. Plasma clonidine concentration data were obtained f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a1e3538c62c20e7954d5dd39e36e97
https://doi.org/10.1177/0091270010370587
https://doi.org/10.1177/0091270010370587
Publikováno v:
Annual Review of Pharmacology and Toxicology. 49:349-375
Microbicides, substances applied topically to prevent sexual HIV infection, are needed to empower receptive sexual partners with effective prevention methods. Several large microbicide trials, however, failed to demonstrate efficacy, thus motivating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dfc769f525fd4f3f16073d9d950e872
https://doi.org/10.1146/annurev.pharmtox.48.113006.094906
https://doi.org/10.1146/annurev.pharmtox.48.113006.094906
Autor:
Ying Jun Cao, Courtney V. Fletcher, Edward J. Fuchs, Themba T. Ndovi, Anita Guidos, Craig W. Hendrix
Publikováno v:
The Journal of Clinical Pharmacology. 47:1366-1373
Food can change drug concentrations by several mechanisms, including some that are independent of absorption effects. This study tests the hypothesis that a meal decreases zidovudine (ZDV) concentration in blood plasma independent of an effect on dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927e3fdd473e087c1cbb6109445936d3
https://doi.org/10.1177/0091270007306562
https://doi.org/10.1177/0091270007306562
Autor:
Ying Jun Cao, Jeong Gun Park, Nimalie D. Stone, Ron MacFarland, Charles Flexner, Beatrice Kallungal, Craig W. Hendrix, Ilene Wiggins, Sally Snyder, Camlin Tierney, Jeanne Conley, Stephen Becker, Christina M. Lalama, Karin L. Klingman, Gary Calandra, Shelia B. Dunaway
Publikováno v:
Antimicrobial Agents and Chemotherapy. 51:2351-2358
AMD070 is an oral CXCR4 antagonist with in vitro activity against X4-tropic human immunodeficiency virus type 1. Thirty fasting healthy male volunteers received oral doses of AMD070 ranging from a single 50-mg dose to seven 400-mg doses given every 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13d810348b127b03f1d7723ff9003fee
https://doi.org/10.1128/aac.00013-07
https://doi.org/10.1128/aac.00013-07
Autor:
Ying Jun, Cao, Taiji, Sawamoto, Udaya, Valluri, Kathy, Cho, Michaelene, Lewand, Suzanne, Swan, Kenneth, Lasseter, Mark, Matson, John, Holman, James, Keirns, Tong, Zhu
Publikováno v:
Clinical pharmacology in drug development. 5(6)
Two randomized, double-blind, placebo-controlled studies are reported that had the objective to evaluate the pharmacokinetics, pharmacodynamics, and safety of ASP015K (peficitinib), a Janus kinase (JAK) inhibitor, in healthy subjects. The single-dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::02647f1846ea3c4448fe4d2ca0cde024
https://pubmed.ncbi.nlm.nih.gov/27162173
https://pubmed.ncbi.nlm.nih.gov/27162173
Autor:
Hemendra N. Bhargava, Ying-Jun Cao
Publikováno v:
Peptides. 19:563-568
The effects of acute and chronic administration of cocaine on the antinociception and tolerance to the antinociceptive actions of mu-(morphine), kappa-(U-50,488H), and delta-([D-Pen2,D-Pen5]enkephalin; DPDPE), opioid receptor agonists were determined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e089d37ce00407bb80585571b3adcbde
https://doi.org/10.1016/s0196-9781(97)00422-1
https://doi.org/10.1016/s0196-9781(97)00422-1