Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ying Jie Lock"'
Autor:
Fabio Petrocca, Judy Lieberman, Peter Smith, Silvia Buonamici, Zach Herbert, Ying Jie Lock, Rory Kirchner, Praveen Sridhar, Stefanie Chan
Table S2: Top siRNA screen hits; Table S10: Summary of validated PRPF8-sensitive transcripts across multiple cell lines; Table S14: BE dosing schedules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5aacf58b5390f1741ad70f437310723
https://doi.org/10.1158/1535-7163.22504696
https://doi.org/10.1158/1535-7163.22504696
Autor:
Fabio Petrocca, Judy Lieberman, Peter Smith, Silvia Buonamici, Zach Herbert, Ying Jie Lock, Rory Kirchner, Praveen Sridhar, Stefanie Chan
Table S6: Differentially expressed transcripts in PRPF8-KD cells;Table S7: Differentially expressed transcripts in PRPF38A-KD cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26fc1ae1b50beb7048d4656b68ef54dd
https://doi.org/10.1158/1535-7163.22504693
https://doi.org/10.1158/1535-7163.22504693
Autor:
Fabio Petrocca, Judy Lieberman, Peter Smith, Silvia Buonamici, Zach Herbert, Ying Jie Lock, Rory Kirchner, Praveen Sridhar, Stefanie Chan
Prognosis of triple-negative breast cancer (TNBC) remains poor. To identify shared and selective vulnerabilities of basal-like TNBC, the most common TNBC subtype, a directed siRNA lethality screen was performed in 7 human breast cancer cell lines, fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::378b3a7b35f110345b4997966cbc31e2
https://doi.org/10.1158/1535-7163.c.6537829.v1
https://doi.org/10.1158/1535-7163.c.6537829.v1
Autor:
Fabio Petrocca, Judy Lieberman, Peter Smith, Silvia Buonamici, Zach Herbert, Ying Jie Lock, Rory Kirchner, Praveen Sridhar, Stefanie Chan
Figure S1: Core RNA splicing genes are frequently up-regulated in basal-like TNBC; Figure S2: PRPF8 and PRPF38A knockdown have similar effect based on gene expression; Figure S3: PRPF8 knockdown promotes G2/M arrest and histone-H3 phosphorylation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd417f7efee4193ffd98d929d747bfee
https://doi.org/10.1158/1535-7163.22504711.v1
https://doi.org/10.1158/1535-7163.22504711.v1
Autor:
Fabio Petrocca, Judy Lieberman, Peter Smith, Silvia Buonamici, Zach Herbert, Ying Jie Lock, Rory Kirchner, Praveen Sridhar, Stefanie Chan
Supplementary Materials and Methods, Figure Legends and Table Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::667dae984a9387c4a0aa0e15307e6557
https://doi.org/10.1158/1535-7163.22504708.v1
https://doi.org/10.1158/1535-7163.22504708.v1
Autor:
William C. Hahn, Peter S. Hammerman, Philip W. Kantoff, Jacob D. Jaffe, Monica Schenone, Steven A. Carr, Emily Hartman, Jinal Patel, Yvonne Y. Li, Michaela Bowden, Isil Guney, Francesca Izzo, Ying Jie Lock, Katherine Labella, Rosina T. Lis, Maura B. Cotter, Anna C. Schinzel, Atish D. Choudhury
In prostate cancer, the development of castration resistance is pivotal in progression to aggressive disease. However, understanding of the pathways involved remains incomplete. In this study, we performed a high-throughput genetic screen to identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be2a33bbe33d1b17db156eb41f1c9a3b
https://doi.org/10.1158/0008-5472.c.6509124.v1
https://doi.org/10.1158/0008-5472.c.6509124.v1
Autor:
William C. Hahn, Peter S. Hammerman, Philip W. Kantoff, Jacob D. Jaffe, Monica Schenone, Steven A. Carr, Emily Hartman, Jinal Patel, Yvonne Y. Li, Michaela Bowden, Isil Guney, Francesca Izzo, Ying Jie Lock, Katherine Labella, Rosina T. Lis, Maura B. Cotter, Anna C. Schinzel, Atish D. Choudhury
Description of additional methods and procedures used in the study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::118fbebf56ec4847929efc392111e170
https://doi.org/10.1158/0008-5472.22414956
https://doi.org/10.1158/0008-5472.22414956
Autor:
William C. Hahn, Peter S. Hammerman, Philip W. Kantoff, Jacob D. Jaffe, Monica Schenone, Steven A. Carr, Emily Hartman, Jinal Patel, Yvonne Y. Li, Michaela Bowden, Isil Guney, Francesca Izzo, Ying Jie Lock, Katherine Labella, Rosina T. Lis, Maura B. Cotter, Anna C. Schinzel, Atish D. Choudhury
GO terms for NEK6 upregulated genes Day 5 after castration (filtered for >10 GeneHits).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475c29a799f988984430ba3b8dd44793
https://doi.org/10.1158/0008-5472.22414944
https://doi.org/10.1158/0008-5472.22414944
Autor:
William C. Hahn, Peter S. Hammerman, Philip W. Kantoff, Jacob D. Jaffe, Monica Schenone, Steven A. Carr, Emily Hartman, Jinal Patel, Yvonne Y. Li, Michaela Bowden, Isil Guney, Francesca Izzo, Ying Jie Lock, Katherine Labella, Rosina T. Lis, Maura B. Cotter, Anna C. Schinzel, Atish D. Choudhury
Legend for Supplemental Figures S1-S6.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a30fb9eb61ed9b6aebf247e8bddd1f
https://doi.org/10.1158/0008-5472.22414962
https://doi.org/10.1158/0008-5472.22414962
Autor:
Ying Jie Lock, Rachel Litman Flynn, Katherine Terranova, Lisa M Carson, Nicholas Lupo, Emily Mason-Osann
Publikováno v:
EMBO Reports
Cancer cells can activate the alternative lengthening of telomeres (ALT) pathway to promote replicative immortality. The ALT pathway promotes telomere elongation through a homologous recombination pathway known as break‐induced replication (BIR), w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b811b3b9efb570899a43eeb9a6e0b53b
https://doi.org/10.15252/embr.201949495
https://doi.org/10.15252/embr.201949495
