Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ying Jie Ai"'
Autor:
Peng Liu, Si-Jia Sun, Ying-Jie Ai, Xu Feng, Yi-Min Zheng, Yun Gao, Jin-Ye Zhang, Lei Zhang, Yi-Ping Sun, Yue Xiong, Miao Lin, Hai-Xin Yuan
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-11 (2022)
Abstract Increased glycolysis is a hallmark of tumor, which can provide tumor cells with energy and building blocks to promote cell proliferation. Recent studies have shown that not only the expression of glycolytic genes but also their subcellular l
Externí odkaz:
https://doaj.org/article/23611dc058cb4a4ca2ba58136cb8053d
Publikováno v:
Journal of Digestive Diseases. 23:577-586
Variceal hemorrhage is a fatal complication of cirrhosis. In this study, we aimed to investigate the role of serum interleukin 2 receptor (sIL-2R) as a predictive indicator in patients with a previous history of cirrhosis-related variceal bleeding.A
ALK fusion promotes metabolic reprogramming of cancer cells by transcriptionally upregulating PFKFB3
Autor:
Mengnan Hu, Ruoxuan Bao, Miao Lin, Xiao-Ran Han, Ying-Jie Ai, Yun Gao, Kun-Liang Guan, Yue Xiong, Hai-Xin Yuan
Publikováno v:
Oncogene. 41:4547-4559
Anaplastic lymphoma kinase (ALK), a receptor tyrosine kinase of the insulin receptor kinase subfamily, is activated in multiple cancer types through translocation or overexpression. Although several generations of ALK tyrosine kinase inhibitors (TKIs
Autor:
Si-Jia Sun, Ying-Jie Ai, Kun-Long Duan, Jin-Ye Zhang, Cheng Zhang, Yi-Ping Sun, Yue Xiong, Kun-Liang Guan, Hai-Xin Yuan
Publikováno v:
Oncogene. 41(50)
TET2 (ten-eleven-translocation) protein is a Fe(II)- and α-ketoglutarate-dependent dioxygenase that catalyzes DNA demethylation to regulate gene expression. While TET2 gene is frequently mutated in hematological cancer, its enzymatic activity is als