Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ying Grace Li"'
Autor:
Charles Benson, Emmanuel Chigutsa, Amit Saxena, Paul Klekotka, Peter Chen, Gourab Datta, Ariel Kay, Josh Poorbaugh, Mark J. Mulligan, William A. Fischer, Ying Grace Li, Karen L. Price, Patricia Brown-Augsburger, Ajay Nirula, Robert J. Benschop, Nadine Rouphael, Jenny Y. Chien, Jeffrey Fill, Michael Dougan
Publikováno v:
Clinical Pharmacology and Therapeutics
Therapeutics for patients hospitalized with coronavirus disease 2019 (COVID-19) are urgently needed during the pandemic. Bamlanivimab is a potent neutralizing monoclonal antibody that blocks severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2
Autor:
Robin S. Scott, Charmian A. Quigley, Sreekumar G Pillai, Ying Grace Li, John S. Parks, Milton R. Brown, Poulabi Banerjee, Werner F. Blum
Publikováno v:
Hormone Research in Paediatrics. 91:164-174
Background/Aims: The term idiopathic short stature (ISS) describes short stature of unknown, but likely polygenic, etiology. This study aimed to identify genetic polymorphisms associated with the ISS phenotype, and with growth response to supplementa
Autor:
Luis Nevárez Ruiz, Zvonko Milicevic, Zhuoxin Yu, Juan P. Frias, Ying Grace Li, David A. Cox, Brad Woodward
Publikováno v:
Journal of the Endocrine Society
Dulaglutide (DU) approved at doses of 0.75 and 1.5 mg once-weekly is an effective glucose lowering agent for treatment of type 2 diabetes (T2D). We hypothesized that higher investigational DU doses may provide further improvements in glucose control
Autor:
Eloise E. Kaizar, Jason C. Hsu, Michael Man, Yi Liu, Stephen J. Ruberg, Szu-Yu Tang, Ying Grace Li
Publikováno v:
Statistics in Biopharmaceutical Research. 8:325-333
In personalized medicine, continuous biomarker values are often dichotomized to classify patients into target and nontarget populations. For example, baseline hemoglobin A1c (A1C) and Positive and Negative Syndrome Scale (PANSS) measurements are pote
Publikováno v:
Ann. Appl. Stat. 12, no. 3 (2018), 1727-1748
Our research is for finding SNPs that are predictive of treatment efficacy, to decide which subgroup (with enhanced treatment efficacy) to target in drug development. Testing SNPs for lack of association with treatment outcome is inherently challengi
Autor:
Xiaoling Xuei, George J. Eckert, Mark A. Deeg, Ying Grace Li, Robert V. Considine, J. Howard Pratt
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1821:381-385
HDL is a heterogeneous mixture of lipoprotein particles varying in composition, size, and function. We and others have described a small (7.0nm), minor (0.1% of total apolipoprotein AI) particle containing apolipoprotein AI, AIV and glycosylphosphati
Autor:
Daniel E. Salazar, Joseph A. Jakubowski, David S Small, Ying Grace Li, John T. Brandt, Kenneth J. Winters, Christopher D. Payne, C. Steven Ernest, Nagy A. Farid
Publikováno v:
Journal of Cardiovascular Pharmacology. 50:555-562
Prasugrel pharmacodynamics and pharmacokinetics after a 60-mg loading dose (LD) and daily 10-mg maintenance doses (MD) were compared in a 3-way crossover study to clopidogrel 600-mg/75-mg and 300-mg/75-mg LD/MD in 41 healthy, aspirin-free subjects. E
Publikováno v:
Clinical pharmacology in drug development. 4(4)
LY500307 is a highly selective estrogen receptor β (ERβ) agonist, which loses its selectivity at high dose and leads to undesirable suppression of total testosterone (TT) concentration. The objective of the present analysis was to define the LY5003