Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ying Gai Tusing"'
Publikováno v:
Stem Cell Research, Vol 55, Iss , Pp 102498- (2021)
iPSCs were generated from B lymphocytes of two Alzheimer’s disease (AD) patients homozygous for the APOE e3 allele. The iPSCs express pluripotency-specific markers and have the capacity to differentiate into all three embryonic germ layers. Karyoty
Externí odkaz:
https://doaj.org/article/6a1a4f9e2cc34f2abf17f9294a16baca
Publikováno v:
Biomolecules, Vol 11, Iss 4, p 577 (2021)
The Ca2+-independent phospholipase A2β (iPLA2β) is a member of the PLA2 family that has been proposed to have roles in multiple biological processes including membrane remodeling, cell proliferation, bone formation, male fertility, cell death, and
Externí odkaz:
https://doaj.org/article/f07516879d81409a83bd4ab432ebfe08
Autor:
Tayleur D. White, Abdulaziz Almutairi, Ying Gai-Tusing, Daniel J. Stephenson, Benjamin D. Stephenson, Charles E. Chalfant, Xiaoyong Lei, Brian Lu, Bruce D. Hammock, Teresa P. DiLorenzo, Sasanka Ramanadham
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionWe reported that Ca2+-independent phospholipase A2β (iPLA2β)–derived lipids (iDLs) contribute to type 1 diabetes (T1D) onset. As CD4+ and CD8+ T cells are critical in promoting β-cell death, we tested the hypothesis that iDL signalin
Externí odkaz:
https://doaj.org/article/588f970bbb8d45fbb26e60d608d19390
Autor:
White, Tayleur D., Almutairi, Abdulaziz, Ying Gai-Tusing, Stephenson, Daniel J., Stephenson, Benjamin D., Chalfant, Charles E., Xiaoyong Lei, Lu, Brian, Hammock, Bruce D., DiLorenzo, Teresa P., Ramanadham, Sasanka
Publikováno v:
Frontiers in Immunology; 2024, p01-14, 14p
Autor:
Suzanne E. Barbour, Tayleur D. White, Ying Gai Tusing, Christopher L. Cardona, Xiaoyong Lei, Sasanka Ramanadham, Abdulaziz Almutairi, Daniel J. Stephenson, Charles E. Chalfant, Margaret A. Park, Alexander J. Nelson
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 2, Pp 143-158 (2020)
Phospholipases A2 (PLA2s) catalyze hydrolysis of the sn-2 substituent from glycerophospholipids to yield a free fatty acid (i.e., arachidonic acid), which can be metabolized to pro- or anti-inflammatory eicosanoids. Macrophages modulate inflammatory
Publikováno v:
Stem Cell Research, Vol 55, Iss, Pp 102498-(2021)
Stem cell research
Stem cell research
iPSCs were generated from B lymphocytes of two Alzheimer's disease (AD) patients homozygous for the APOE e3 allele. The iPSCs express pluripotency-specific markers and have the capacity to differentiate into all three embryonic germ layers. Karyotypi
Publikováno v:
Biomolecules, Vol 11, Iss 577, p 577 (2021)
Biomolecules
Biomolecules
The Ca2+-independent phospholipase A2β (iPLA2β) is a member of the PLA2 family that has been proposed to have roles in multiple biological processes including membrane remodeling, cell proliferation, bone formation, male fertility, cell death, and
Autor:
Joanna Kramer, George Kokotos, Charles E. Chalfant, Sasanka Ramanadham, Martin J. Hessner, Alexander J. Nelson, Christopher L. Cardona, Clayton E. Mathews, Margaret A. Park, Daniel J. Stephenson, Xiaoyong Lei, Robert N. Bone, Ying Gai Tusing, Christina L. Graves
Publikováno v:
JCI Insight
JCI Insight, Vol 5, Iss 16 (2020)
JCI Insight, Vol 5, Iss 16 (2020)
Type 1 diabetes (T1D) is a consequence of autoimmune β cell destruction, but the role of lipids in this process is unknown. We previously reported that activation of Ca2+-independent phospholipase A2β (iPLA2β) modulates polarization of macrophages