Zobrazeno 1 - 10
of 123
pro vyhledávání: '"Ying‐Ray Lee"'
Autor:
Pei‐Wen Lin, Man‐Ling Chu, Yu‐Wen Liu, Yu‐Cing Chen, Yao‐Hsiang Shih, Sheng‐Hui Lan, Shang‐Ying Wu, I‐Ying Kuo, Hong‐Yi Chang, Hsiao‐Sheng Liu, Ying‐Ray Lee
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 7, Pp 642-649 (2024)
Abstract Autophagy can be classified as degradative and secretory based on distinct functions. The small GTPase proteins Rab8a and Rab37 are responsible for secretory autophagy‐mediated exocytosis of IL‐1β, insulin, and TIMP1 (tissue inhibitor o
Externí odkaz:
https://doaj.org/article/e258c7ae7ddd4ed3a3137a5a976dbe9c
Autor:
Hsiao‐Sheng Liu, Yin‐Ping Wang, Pei‐Wen Lin, Man‐Ling Chu, Sheng‐Hui Lan, Shan‐Ying Wu, Ying‐Ray Lee, Hong‐Yi Chang
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 7, Pp 631-641 (2024)
Abstract Autophagy is a self‐recycling machinery to maintain cellular homeostasis by degrading harmful materials in the cell. Autophagy‐related gene 5 (Atg5) is required for autophagosome maturation. However, the role of Atg5 in tumorigenesis und
Externí odkaz:
https://doaj.org/article/f842293ee22c4ac499453b39c2812390
Autor:
Tsung-Hsing Lin, Chin-Ho Kuo, Yi-Sheng Zhang, Pin-Tzu Chen, Shu-Hsin Chen, Yi-Zhen Li, Ying-Ray Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8048 (2023)
Thyroid cancer (TC) is the most common endocrine malignancy. Recently, the global incidence of TC has increased rapidly. Differentiated thyroid cancer includes papillary thyroid carcinoma (PTC) and follicular thyroid carcinoma (FTC), which are the mo
Externí odkaz:
https://doaj.org/article/e0435f05e1a84daea2f586c40522a81f
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 36, Iss 11, Pp 911-919 (2020)
Abstract We previously reported that dengue virus (DENV)‐induced autophagy plays a promoting role in viral replication and pathogenesis both in vitro and in vivo. Although it is known that DENV infection increases glycolysis, which promotes viral r
Externí odkaz:
https://doaj.org/article/8e62004f53da45b1aad2343d943728b4
Autor:
Yuan-Chieh Yeh, Ly Hien Doan, Zi-Yi Huang, Li-Wei Chu, Tzu-Hau Shi, Ying-Ray Lee, Cheng-Tao Wu, Chao-Hsiung Lin, Shu-Tuan Chiang, Hui-Kang Liu, Tsung-Hsien Chuang, Yueh-Hsin Ping, Hsiao-Sheng Liu, Chi-Ying F. Huang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
COVID-19 is threatening human health worldwide but no effective treatment currently exists for this disease. Current therapeutic strategies focus on the inhibition of viral replication or using anti-inflammatory/immunomodulatory compounds to improve
Externí odkaz:
https://doaj.org/article/4d184f88a03e480a94e0605248bc7332
Autor:
Ying-Ray Lee, Huey-Pin Tsai, Chun-Sheng Yeh, Chiung-Yao Fang, Michael W. Y. Chan, Tzu-Yun Wu, Cheng-Huang Shen
Publikováno v:
Viruses, Vol 15, Iss 1, p 100 (2022)
COVID-19, caused by SARS-CoV-2, created a devastating outbreak worldwide and consequently became a global health concern. However, no verifiable, specifically targeted treatment has been devised for COVID-19. Several emerging vaccines have been used,
Externí odkaz:
https://doaj.org/article/70e365e651cf4eadaad5a2fc78dd4b94
Autor:
Hsiang-Hao Chuang, Ming-Shyan Huang, Yen-Yi Zhen, Cheng-Hao Chuang, Ying-Ray Lee, Michael Hsiao, Chih-Jen Yang
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1937 (2022)
Focal adhesion kinase (FAK) is a non-receptor tyrosine kinase overexpressed in various cancer types that plays a critical role in tumor progression. Accumulating evidence suggests that targeting FAK, either alone or in combination with other agents,
Externí odkaz:
https://doaj.org/article/2e649a6dbfd941bb9de33c8295f41195
Autor:
Shan-Ying Wu, Yu-Lun Chen, Ying-Ray Lee, Chiou-Feng Lin, Sheng-Hui Lan, Kai-Ying Lan, Man-Ling Chu, Pei-Wen Lin, Zong-Lin Yang, Yen-Hsu Chen, Wen-Hung Wang, Hsiao-Sheng Liu
Publikováno v:
Viruses, Vol 13, Iss 10, p 2034 (2021)
Autophagic machinery is involved in selective and non-selective recruitment as well as degradation or exocytosis of cargoes, including pathogens. Dengue virus (DENV) infectioninduces autophagy that enhances virus replication and vesicle release to ev
Externí odkaz:
https://doaj.org/article/6504f4ad4c0444fa8196ba9740457ade
Autor:
Jia-Ming Chang, Jin-Yi Wu, Shu-Hsin Chen, Wen-Ying Chao, Hsiang-Hao Chuang, Kam-Hong Kam, Pei-Wen Zhao, Yi-Zhen Li, Yu-Pei Yen, Ying-Ray Lee
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9864 (2021)
Lung cancer is one of the most common cancers and the leading cause of death in humans worldwide. Non-small-cell lung cancer (NSCLC) accounts for approximately 85% of lung cancer cases and is often diagnosed at a late stage. Among patients with NSCLC
Externí odkaz:
https://doaj.org/article/fd28f8fcb7014f53aed19179e55b07c5
Autor:
Ying-Ray Lee, Chia-Ming Chang, Yuan-Chieh Yeh, Chi-Ying F. Huang, Feng-Mao Lin, Juan-Ting Huang, Chang-Chi Hsieh, Jen-Ren Wang, Hsiao-Sheng Liu
Publikováno v:
Viruses, Vol 13, Iss 2, p 308 (2021)
Honeysuckle (Lonicera japonica Thunb) is a traditional Chinese medicine (TCM) with an antipathogenic activity. MicroRNAs (miRNAs) are small non-coding RNA molecules that are ubiquitously expressed in cells. Endogenous miRNA may function as an innate
Externí odkaz:
https://doaj.org/article/c2ceb1de32cd498ca8781f73e03e1f21