Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Yina Kuang"'
Autor:
Randall A. Ow, Steven Shotts, Venkata Kakarlapudi, John McIntyre, Robert M. Naclerio, Changcheng You, Alexander Pappas, Lindsay Brayton, Yina Kuang, James Shao
Publikováno v:
American Journal of Rhinology & Allergy. 36:733-740
Background The efficacy of topical corticosteroids is limited in chronic rhinosinusitis (CRS) due to rapid clearance from the nasal cavity and insufficient drug delivery to inflamed sinonasal passages. LYR-210 is an implantable corticosteroid matrix
Publikováno v:
International Forum of Allergy & Rhinology. 12:147-159
Background Topical steroids are first-line treatment for chronic rhinosinusitis (CRS), but fail to provide adequate symptom control for all patients. Designed for medical treatment failures, LYR-210 is an implantable matrix that locally elutes mometa
Publikováno v:
American Journal of Rhinology & Allergy. 36:198-206
Background Intranasal corticosteroid sprays (INCSs) used to treat chronic rhinosinusitis are suboptimal due to limited penetration into the middle meatus, rapid clearance, and poor patient compliance. A bioresorbable drug matrix, developed with the X
Autor:
Joanne Rimmer, Alkis J. Psaltis, Richard G. Douglas, Anders Cervin, Yina Kuang, Tom Kuruvilla
Publikováno v:
International forum of allergyrhinology. 9(4)
Background: Chronic rhinosinusitis (CRS) patients who fail medical management have few treatment options other than endoscopic sinus surgery (ESS). A novel biodegradable mometasone furoate drug delivery system (LYR-210) providing continuous topical s
Autor:
Rany Busold, Upma Sharma, Greg Zugates, Danny Concagh, Robert Langer, Jonathan Merlo, Changcheng You, Stephanie Webber, Yina Kuang, Quynh Pham, Lee Core, George M. Whitesides, Maria Palasis
Publikováno v:
Nature materials. 17(1)
Implants for the treatment of tissue defects should mimic the mechanical properties of the native tissue of interest and should be resorbable as well as biocompatible. In this work, we developed a scaffold from variants of poly(glycolic) acid which w
Publikováno v:
Analytical Chemistry. 76:6282-6286
An optical fiber based well array platform was used for simultaneous, dynamic gene expression monitoring from hundreds of individual live Escherichia coli cells carrying promoter-fluorescent reporter gene fusions. High information content about gene
Autor:
Tomoaki Kanaya, Wendy Naimark, Guilherme F. Attizzani, Maria Palasis, Marco Costa, Hiram G. Bezerra, Daniel Chamié, Kentaro Tanaka, Yina Kuang, Yusuke Fujino
Publikováno v:
Journal of the American College of Cardiology. 61(10)
Autor:
Yina Kuang, David R. Walt
Publikováno v:
Biotechnology and bioengineering. 96(2)
We describe a strategy for the preparation and self-assembly of fluorescent nanosensors onto Saccharomyces cerevisiae cell surfaces for dynamically measuring oxygen concentration in the proximity of living cells. Amine functionalized polystyrene nano
Autor:
David R. Walt, James J. Collins, Gábor Balázsi, Michael A. Kohanski, Kevin F. Murphy, William Jeremy Blake, Farren J. Isaacs, Yina Kuang, Charles R. Cantor
Publikováno v:
Molecular cell. 24(6)
A more complete understanding of the causes and effects of cell-cell variability in gene expression is needed to elucidate whether the resulting phenotypes are disadvantageous or confer some adaptive advantage. Here we show that increased variability
Autor:
Yina Kuang, David R. Walt
Publikováno v:
Analytical biochemistry. 345(2)
Recent advances in genomics and molecular pathogenesis studies have determined that many diseases are caused by a multiplicity of factors. New drug regimens may consist of multiple biologically active agents designed to act synergistically on multipl